PT101876A - Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida - Google Patents

Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida Download PDF

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Publication number
PT101876A
PT101876A PT101876A PT10187696A PT101876A PT 101876 A PT101876 A PT 101876A PT 101876 A PT101876 A PT 101876A PT 10187696 A PT10187696 A PT 10187696A PT 101876 A PT101876 A PT 101876A
Authority
PT
Portugal
Prior art keywords
azepine
dibenzo
carboxamide
dihydro
oxo
Prior art date
Application number
PT101876A
Other languages
English (en)
Other versions
PT101876B (pt
Inventor
Jan Benes
David Alexander Learmonth
Original Assignee
Portela & Ca Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Portela & Ca Sa filed Critical Portela & Ca Sa
Priority to PT101876A priority Critical patent/PT101876B/pt
Priority to US08/862,196 priority patent/US5866566A/en
Priority to MXPA/A/1997/003846A priority patent/MXPA97003846A/xx
Priority to SI9730129T priority patent/SI0810216T1/xx
Priority to ES97108465T priority patent/ES2156319T3/es
Priority to AT97108465T priority patent/ATE199901T1/de
Priority to DK97108465T priority patent/DK0810216T3/da
Priority to DE69704297T priority patent/DE69704297T2/de
Priority to ARP970102233A priority patent/AR007291A1/es
Priority to EP97108465A priority patent/EP0810216B1/en
Priority to AU29740/97A priority patent/AU713807B2/en
Priority to PL97330141A priority patent/PL189298B1/pl
Priority to RU98123571/04A priority patent/RU2187503C2/ru
Priority to JP13716397A priority patent/JP3592892B2/ja
Priority to CN97196803A priority patent/CN1101382C/zh
Priority to TR1998/02462T priority patent/TR199802462T2/xx
Priority to PCT/IB1997/000691 priority patent/WO1997045416A1/en
Priority to CA002206172A priority patent/CA2206172C/en
Priority to BRPI9703403-7A priority patent/BR9703403B1/pt
Publication of PT101876A publication Critical patent/PT101876A/pt
Publication of PT101876B publication Critical patent/PT101876B/pt
Priority to GR20010400764T priority patent/GR3035910T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/30—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PT101876A 1996-05-27 1996-05-27 Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida PT101876B (pt)

Priority Applications (20)

Application Number Priority Date Filing Date Title
PT101876A PT101876B (pt) 1996-05-27 1996-05-27 Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
US08/862,196 US5866566A (en) 1996-05-27 1997-05-23 Derivatives of 10, 11-Dihydro-10-OXO-5H-Dibenz/B,F/Azepine-5-carboxamide
EP97108465A EP0810216B1 (en) 1996-05-27 1997-05-26 Derivatives of 10,11-dihydro-10-oxo-5h-dibenz/b,f/azepine-5-carboxamide
SI9730129T SI0810216T1 (pt) 1996-05-27 1997-05-26
ES97108465T ES2156319T3 (es) 1996-05-27 1997-05-26 Derivados de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepin-5-carboxamida.
AT97108465T ATE199901T1 (de) 1996-05-27 1997-05-26 10,11-dihydro-10-oxo-5h-dibenz(b,f)azepin-5- carboxamidderivate
DK97108465T DK0810216T3 (da) 1996-05-27 1997-05-26 Derivater af 10,11-dihydro-10-oxo-5H-dibenz/b/,f/azepin-5-carboxamid
DE69704297T DE69704297T2 (de) 1996-05-27 1997-05-26 10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepin-5-carboxamidderivate
ARP970102233A AR007291A1 (es) 1996-05-27 1997-05-26 Nuevos derivados de 10,11-dihidro-10-oxo-5h-dibenz/b, f/azepina-5-carboxamida, metodo de preparacion y su uso en la preparacion de una composicion farmaceutica
MXPA/A/1997/003846A MXPA97003846A (es) 1996-05-27 1997-05-26 Nuevos derivados de 10, 11-dihidro-10-oxo-5h-dibenz/b, f/azepina-5-carboxamida
PL97330141A PL189298B1 (pl) 1996-05-27 1997-05-27 Nowe pochodne 10,11-dihydro-10-okso-5H-dibenzo/b,f/-azepino-5-karboksyamidu, sposób ich wytwarzaniai zawierające je kompozycje farmaceutyczne
AU29740/97A AU713807B2 (en) 1996-05-27 1997-05-27 New derivatives of 10,11-dihydro-10-oxo-5h-dibenz/b,f/aze pine-5-carboxamide
RU98123571/04A RU2187503C2 (ru) 1996-05-27 1997-05-27 Новые производные 10,11-дигидро-10-оксо-5h-дибенз[b,f]азепин-5-карбоксамида, способы их получения, фармацевтическая композиция, способ лечения судорожных состояний
JP13716397A JP3592892B2 (ja) 1996-05-27 1997-05-27 １０，１１−ジヒドロ−１０−オキソ−５Ｈ−ジベンズ／ｂ，ｆ／アゼピン−５−カルボキサミドの新規な誘導体
CN97196803A CN1101382C (zh) 1996-05-27 1997-05-27 10,11－二氢－10－氧－5H－二苯并/b,f/氮杂䓬－5－甲酰胺衍生物
TR1998/02462T TR199802462T2 (xx) 1996-05-27 1997-05-27 10,11-Dihidro-10-okso-5H-dibenz/ b, F/azepin-5-karboksamidin yeni t�revleri.
PCT/IB1997/000691 WO1997045416A1 (en) 1996-05-27 1997-05-27 NEW DERIVATIVES OF 10,11-DIHYDRO-10-OXO-5H-DIBENZ/b,F/AZEPINE-5-CARBOXAMIDE
CA002206172A CA2206172C (en) 1996-05-27 1997-05-27 New derivatives of 10,11-dihydro-10-oxo-5h-dibenz/b,f/azepine-5-carboxamide
BRPI9703403-7A BR9703403B1 (pt) 1996-05-27 1997-05-27 compostos, processo para preparação de compostos, utilização de composto e processo para preparação de composição farmacêutica.
GR20010400764T GR3035910T3 (en) 1996-05-27 2001-05-22 Derivatives of 10,11-dihydro-10-oxo-5h-dibenz/b,f/azepine-5-carboxamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT101876A PT101876B (pt) 1996-05-27 1996-05-27 Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida

Publications (2)

Publication Number Publication Date
PT101876A true PT101876A (pt) 1997-12-31
PT101876B PT101876B (pt) 1999-09-30

Family

ID=20085604

Family Applications (1)

Application Number Title Priority Date Filing Date
PT101876A PT101876B (pt) 1996-05-27 1996-05-27 Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida

Country Status (19)

Country Link
US (1) US5866566A (pt)
EP (1) EP0810216B1 (pt)
JP (1) JP3592892B2 (pt)
CN (1) CN1101382C (pt)
AR (1) AR007291A1 (pt)
AT (1) ATE199901T1 (pt)
AU (1) AU713807B2 (pt)
BR (1) BR9703403B1 (pt)
CA (1) CA2206172C (pt)
DE (1) DE69704297T2 (pt)
DK (1) DK0810216T3 (pt)
ES (1) ES2156319T3 (pt)
GR (1) GR3035910T3 (pt)
PL (1) PL189298B1 (pt)
PT (1) PT101876B (pt)
RU (1) RU2187503C2 (pt)
SI (1) SI0810216T1 (pt)
TR (1) TR199802462T2 (pt)
WO (1) WO1997045416A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9930058D0 (en) * 1999-12-20 2000-02-09 Novartis Ag Organic compounds
AU2004203644B2 (en) * 1999-12-20 2008-04-17 Novartis Ag Pharmaceutical compositions
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) * 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
CH649080A5 (de) * 1981-04-16 1985-04-30 Ciba Geigy Ag 5h-dibenz(b,f)azepin-5-carboxamide als mittel zur prophylaxe und behandlung von zerebraler leistungsinsuffizienz.
US5466683A (en) * 1994-08-25 1995-11-14 Teva Pharmaceutical Industries Ltd. Water-soluble analogs of carbamazepine

Also Published As

Publication number Publication date
EP0810216B1 (en) 2001-03-21
CA2206172C (en) 2002-07-16
BR9703403B1 (pt) 2010-06-29
PL189298B1 (pl) 2005-07-29
AU2974097A (en) 1998-01-05
JPH1081669A (ja) 1998-03-31
RU2187503C2 (ru) 2002-08-20
PT101876B (pt) 1999-09-30
CA2206172A1 (en) 1997-11-27
SI0810216T1 (pt) 2001-08-31
MX9703846A (es) 1998-06-30
DK0810216T3 (da) 2001-07-23
ES2156319T3 (es) 2001-06-16
EP0810216A1 (en) 1997-12-03
DE69704297T2 (de) 2001-09-20
BR9703403A (pt) 1998-09-15
WO1997045416A1 (en) 1997-12-04
AR007291A1 (es) 1999-10-27
DE69704297D1 (de) 2001-04-26
CN1101382C (zh) 2003-02-12
CN1226234A (zh) 1999-08-18
TR199802462T2 (xx) 2000-07-21
ATE199901T1 (de) 2001-04-15
JP3592892B2 (ja) 2004-11-24
US5866566A (en) 1999-02-02
AU713807B2 (en) 1999-12-09
GR3035910T3 (en) 2001-08-31
PL330141A1 (en) 1999-04-26

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Date Code Title Description
BB1A Laying open of patent application

Effective date: 19961112

FG3A Patent granted, date of granting

Effective date: 19990615

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20101129