ES2156319T3 - Derivados de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepin-5-carboxamida. - Google Patents

Derivados de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepin-5-carboxamida.

Info

Publication number
ES2156319T3
ES2156319T3 ES97108465T ES97108465T ES2156319T3 ES 2156319 T3 ES2156319 T3 ES 2156319T3 ES 97108465 T ES97108465 T ES 97108465T ES 97108465 T ES97108465 T ES 97108465T ES 2156319 T3 ES2156319 T3 ES 2156319T3
Authority
ES
Spain
Prior art keywords
derivatives
carboxamida
dihidro
dibenz
azepin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97108465T
Other languages
English (en)
Inventor
Jan Benes
Patricio Manue Soares-Da-Silva
David Alexander Learmonth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bial Portela and Cia SA
Original Assignee
Bial Portela and Cia SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Portela and Cia SA filed Critical Bial Portela and Cia SA
Application granted granted Critical
Publication of ES2156319T3 publication Critical patent/ES2156319T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C07D223/30—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

SE DESCRIBEN COMPUESTOS DE LA FORMULA GENERAL I: ASI COMO UN PROCESO PARA SU PREPARACION QUE CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA II: CON HIDROXILAMINA O SUS DERIVADOS DE FORMULA III: LOS COMPUESTOS CITADOS EN LA PRESENTE INVENCION POSEEN PROPIEDADES FARMACEUTICAS VALIOSAS, PRINCIPALMENTE EN EL TRATAMIENTO DE ALGUNOS TRASTORNOS DEL SISTEMA NERVIOSO PERIFERICO Y CENTRAL.
ES97108465T 1996-05-27 1997-05-26 Derivados de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepin-5-carboxamida. Expired - Lifetime ES2156319T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT101876A PT101876B (pt) 1996-05-27 1996-05-27 Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida

Publications (1)

Publication Number Publication Date
ES2156319T3 true ES2156319T3 (es) 2001-06-16

Family

ID=20085604

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97108465T Expired - Lifetime ES2156319T3 (es) 1996-05-27 1997-05-26 Derivados de 10,11-dihidro-10-oxo-5h-dibenz/b,f/azepin-5-carboxamida.

Country Status (19)

Country Link
US (1) US5866566A (es)
EP (1) EP0810216B1 (es)
JP (1) JP3592892B2 (es)
CN (1) CN1101382C (es)
AR (1) AR007291A1 (es)
AT (1) ATE199901T1 (es)
AU (1) AU713807B2 (es)
BR (1) BR9703403B1 (es)
CA (1) CA2206172C (es)
DE (1) DE69704297T2 (es)
DK (1) DK0810216T3 (es)
ES (1) ES2156319T3 (es)
GR (1) GR3035910T3 (es)
PL (1) PL189298B1 (es)
PT (1) PT101876B (es)
RU (1) RU2187503C2 (es)
SI (1) SI0810216T1 (es)
TR (1) TR199802462T2 (es)
WO (1) WO1997045416A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004203644B2 (en) * 1999-12-20 2008-04-17 Novartis Ag Pharmaceutical compositions
GB9930058D0 (en) * 1999-12-20 2000-02-09 Novartis Ag Organic compounds
GB0112812D0 (en) * 2001-05-25 2001-07-18 Portela & Ca Sa Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH500196A (de) * 1969-03-10 1970-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
FI75561C (fi) * 1979-10-30 1988-07-11 Ciba Geigy Ag Foerfarande foer framstaellning av 5- karbamoyl-10-oxo-10,11-dihydro-5h-dibens/b,f/azepin och daertill noedvaendiga mellanprodukter.
CH649080A5 (de) * 1981-04-16 1985-04-30 Ciba Geigy Ag 5h-dibenz(b,f)azepin-5-carboxamide als mittel zur prophylaxe und behandlung von zerebraler leistungsinsuffizienz.
US5466683A (en) * 1994-08-25 1995-11-14 Teva Pharmaceutical Industries Ltd. Water-soluble analogs of carbamazepine

Also Published As

Publication number Publication date
AU713807B2 (en) 1999-12-09
PT101876B (pt) 1999-09-30
GR3035910T3 (en) 2001-08-31
JP3592892B2 (ja) 2004-11-24
WO1997045416A1 (en) 1997-12-04
CA2206172A1 (en) 1997-11-27
AU2974097A (en) 1998-01-05
SI0810216T1 (es) 2001-08-31
BR9703403B1 (pt) 2010-06-29
JPH1081669A (ja) 1998-03-31
PL189298B1 (pl) 2005-07-29
BR9703403A (pt) 1998-09-15
DE69704297T2 (de) 2001-09-20
CA2206172C (en) 2002-07-16
PL330141A1 (en) 1999-04-26
AR007291A1 (es) 1999-10-27
DK0810216T3 (da) 2001-07-23
US5866566A (en) 1999-02-02
PT101876A (pt) 1997-12-31
EP0810216A1 (en) 1997-12-03
CN1101382C (zh) 2003-02-12
RU2187503C2 (ru) 2002-08-20
MX9703846A (es) 1998-06-30
ATE199901T1 (de) 2001-04-15
TR199802462T2 (xx) 2000-07-21
DE69704297D1 (de) 2001-04-26
EP0810216B1 (en) 2001-03-21
CN1226234A (zh) 1999-08-18

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