KR100255739B1 - 2,3,4,5-테트라하이드로-1h-3-벤즈아제핀과 약제학적으로 허용되는 이의 산 부가염 및 이들을 함유하는 약제학적 조성물 - Google Patents

2,3,4,5-테트라하이드로-1h-3-벤즈아제핀과 약제학적으로 허용되는 이의 산 부가염 및 이들을 함유하는 약제학적 조성물 Download PDF

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Publication number
KR100255739B1
KR100255739B1 KR1019940702944A KR19940702944A KR100255739B1 KR 100255739 B1 KR100255739 B1 KR 100255739B1 KR 1019940702944 A KR1019940702944 A KR 1019940702944A KR 19940702944 A KR19940702944 A KR 19940702944A KR 100255739 B1 KR100255739 B1 KR 100255739B1
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KR
South Korea
Prior art keywords
compound
formula
tetrahydro
chloro
methyl
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KR1019940702944A
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English (en)
Korean (ko)
Other versions
KR950700286A (ko
Inventor
포게트 크리스티안
홀베크 롤프
바르드룸닐센 에릭
Original Assignee
한센 핀 베네드
노보 노르디스크 에이/에스
안네 제헤르
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of KR950700286A publication Critical patent/KR950700286A/ko
Application granted granted Critical
Publication of KR100255739B1 publication Critical patent/KR100255739B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
KR1019940702944A 1992-02-24 1993-02-05 2,3,4,5-테트라하이드로-1h-3-벤즈아제핀과 약제학적으로 허용되는 이의 산 부가염 및 이들을 함유하는 약제학적 조성물 KR100255739B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK233/92 1992-02-24
DK92233A DK23392D0 (da) 1992-02-24 1992-02-24 Heterocykliske forbindelser, deres anvendelse og fremstilling
PCT/DK1993/000041 WO1993017012A1 (en) 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-3-benzazepines and pharmaceutically acceptable acid addition salts thereof

Publications (2)

Publication Number Publication Date
KR950700286A KR950700286A (ko) 1995-01-16
KR100255739B1 true KR100255739B1 (ko) 2000-05-01

Family

ID=8091236

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940702944A KR100255739B1 (ko) 1992-02-24 1993-02-05 2,3,4,5-테트라하이드로-1h-3-벤즈아제핀과 약제학적으로 허용되는 이의 산 부가염 및 이들을 함유하는 약제학적 조성물

Country Status (23)

Country Link
EP (1) EP0628039B1 (ru)
JP (1) JPH07504172A (ru)
KR (1) KR100255739B1 (ru)
AT (1) ATE152450T1 (ru)
AU (1) AU667878B2 (ru)
BG (1) BG62208B1 (ru)
CA (1) CA2130678C (ru)
CZ (1) CZ288626B6 (ru)
DE (1) DE69310353T2 (ru)
DK (2) DK23392D0 (ru)
ES (1) ES2102019T3 (ru)
FI (1) FI113770B (ru)
GR (1) GR3023896T3 (ru)
HU (1) HU221314B1 (ru)
IL (1) IL104657A (ru)
NO (1) NO310193B1 (ru)
NZ (1) NZ249465A (ru)
RO (1) RO116088B1 (ru)
RU (1) RU2114839C1 (ru)
SK (1) SK281390B6 (ru)
UA (1) UA34451C2 (ru)
WO (1) WO1993017012A1 (ru)
ZA (1) ZA931099B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1945495A (en) * 1994-03-16 1995-10-03 Novo Nordisk A/S Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
PL325514A1 (en) * 1995-09-15 1998-08-03 Novo Nordisk As Addition salts formed with acids of 2,3,4,5-tetrahydro-1h-3-benzazepinic compounds
GB0130576D0 (en) * 2001-12-20 2002-02-06 Cenes Ltd Dopamine D1 receptor agonist pro-drug compounds & derivatives
WO2014066659A1 (en) 2012-10-25 2014-05-01 Tetra Discovery Partners, Llc. Heteroaryl inhibitors of pde4
WO2015048407A1 (en) * 2013-09-26 2015-04-02 Tetra Discovery Partners, LLC Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK180485D0 (da) * 1985-04-22 1985-04-23 Novo Industri As Nitrogenholdige forbindelser
DK325188D0 (da) * 1988-06-15 1988-06-15 Novo Industri As Hidtil ukendte benzazepinderivater
DK67489D0 (da) * 1989-02-14 1989-02-14 Novo Industri As Nye benzazepinderivater

Also Published As

Publication number Publication date
DK23392D0 (da) 1992-02-24
NO943123D0 (no) 1994-08-24
HUT71127A (en) 1995-11-28
BG62208B1 (bg) 1999-05-31
RO116088B1 (ro) 2000-10-30
CZ288626B6 (cs) 2001-08-15
FI113770B (fi) 2004-06-15
ZA931099B (en) 1994-08-17
NO310193B1 (no) 2001-06-05
DK0628039T3 (da) 1997-12-08
SK100094A3 (en) 1995-04-12
EP0628039B1 (en) 1997-05-02
AU667878B2 (en) 1996-04-18
HU9402434D0 (en) 1994-10-28
NO943123L (no) 1994-08-24
JPH07504172A (ja) 1995-05-11
DE69310353D1 (de) 1997-06-05
RU2114839C1 (ru) 1998-07-10
WO1993017012A1 (en) 1993-09-02
BG98993A (bg) 1995-05-31
AU3626593A (en) 1993-09-13
DE69310353T2 (de) 1997-10-02
RU94040719A (ru) 1996-07-10
FI943875A (fi) 1994-08-23
IL104657A0 (en) 1993-06-10
SK281390B6 (sk) 2001-03-12
CA2130678A1 (en) 1993-08-25
CA2130678C (en) 2004-04-20
KR950700286A (ko) 1995-01-16
IL104657A (en) 1999-11-30
EP0628039A1 (en) 1994-12-14
NZ249465A (en) 1996-02-27
FI943875A0 (fi) 1994-08-23
HU221314B1 (en) 2002-09-28
ATE152450T1 (de) 1997-05-15
ES2102019T3 (es) 1997-07-16
UA34451C2 (ru) 2001-03-15
CZ198894A3 (en) 1995-10-18
GR3023896T3 (en) 1997-09-30

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