FI112915B - Menetelmä kuivakäsiteltyjen partikkelien valmistamiseksi - Google Patents

Menetelmä kuivakäsiteltyjen partikkelien valmistamiseksi Download PDF

Info

Publication number
FI112915B
FI112915B FI942222A FI942222A FI112915B FI 112915 B FI112915 B FI 112915B FI 942222 A FI942222 A FI 942222A FI 942222 A FI942222 A FI 942222A FI 112915 B FI112915 B FI 112915B
Authority
FI
Finland
Prior art keywords
biocompatible polymer
active ingredient
microspheres
polymer
carrier phase
Prior art date
Application number
FI942222A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI942222L (fi
FI942222A0 (fi
Inventor
Jean-Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of FI942222A0 publication Critical patent/FI942222A0/fi
Publication of FI942222L publication Critical patent/FI942222L/fi
Application granted granted Critical
Publication of FI112915B publication Critical patent/FI112915B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
FI942222A 1993-05-15 1994-05-13 Menetelmä kuivakäsiteltyjen partikkelien valmistamiseksi FI112915B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9310030 1993-05-15
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (3)

Publication Number Publication Date
FI942222A0 FI942222A0 (fi) 1994-05-13
FI942222L FI942222L (fi) 1994-11-16
FI112915B true FI112915B (fi) 2004-02-13

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
FI942222A FI112915B (fi) 1993-05-15 1994-05-13 Menetelmä kuivakäsiteltyjen partikkelien valmistamiseksi

Country Status (35)

Country Link
JP (1) JP3139913B2 (enrdf_load_html_response)
KR (1) KR100341261B1 (enrdf_load_html_response)
CN (1) CN1050534C (enrdf_load_html_response)
AT (1) AT406017B (enrdf_load_html_response)
AU (1) AU685094B2 (enrdf_load_html_response)
BE (1) BE1008323A3 (enrdf_load_html_response)
BR (1) BR9401968A (enrdf_load_html_response)
CA (1) CA2123481C (enrdf_load_html_response)
CH (1) CH688572A5 (enrdf_load_html_response)
DE (1) DE4416812C2 (enrdf_load_html_response)
DK (1) DK171454B1 (enrdf_load_html_response)
DZ (1) DZ1779A1 (enrdf_load_html_response)
ES (1) ES2097083B1 (enrdf_load_html_response)
FI (1) FI112915B (enrdf_load_html_response)
FR (1) FR2705232B1 (enrdf_load_html_response)
GB (2) GB9310030D0 (enrdf_load_html_response)
GR (1) GR1002034B (enrdf_load_html_response)
HK (1) HK1002831A1 (enrdf_load_html_response)
HU (1) HU220617B1 (enrdf_load_html_response)
IE (1) IE940392A1 (enrdf_load_html_response)
IN (1) IN182330B (enrdf_load_html_response)
IT (1) IT1269508B (enrdf_load_html_response)
LU (1) LU88482A1 (enrdf_load_html_response)
MA (1) MA23194A1 (enrdf_load_html_response)
NL (1) NL9400795A (enrdf_load_html_response)
NO (1) NO307403B1 (enrdf_load_html_response)
NZ (1) NZ260520A (enrdf_load_html_response)
OA (1) OA09939A (enrdf_load_html_response)
PL (1) PL175780B1 (enrdf_load_html_response)
PT (1) PT101518B (enrdf_load_html_response)
RU (1) RU2125869C1 (enrdf_load_html_response)
SE (1) SE519004C2 (enrdf_load_html_response)
SG (1) SG46631A1 (enrdf_load_html_response)
TN (1) TNSN94046A1 (enrdf_load_html_response)
ZA (1) ZA943316B (enrdf_load_html_response)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2185393C2 (ru) * 1993-01-06 2002-07-20 Кинертон Лимитед Сложный полиэфир и конъюгат на его основе
EP1203591B1 (en) * 1993-01-06 2007-12-19 Ipsen Manufacturing Ireland Limited biodegradable polyesters for forming ionic molecular conjugates with bioactive polypeptides
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
RU2246293C2 (ru) * 1999-06-14 2005-02-20 Космо С.П.А. Фармацевтические композиции для перорального введения с регулируемым высвобождением активного ингредиента и маскируемым вкусом
AU1375301A (en) 1999-11-15 2001-05-30 Bio Syntech Canada Inc Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
US6646083B2 (en) 2000-06-16 2003-11-11 Nippon Shokubai Co., Ltd. Crosslinked polymers containing tertiary amine and/or quaternary ammonium salt structures, processes for making and uses thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH468192A (de) * 1964-06-19 1969-02-15 Ciba Geigy Verfahren zur Herstellung von Arzneimitteln in Perlenform
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (enrdf_load_html_response) * 1987-10-14 1990-01-15 Debiopharm Sa
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
KR0168849B1 (ko) * 1990-04-12 1999-01-15 요시또시 가즈오 피목 조성물 및 그의 제조방법
JP3116311B2 (ja) * 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE9101603L (sv) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm Metod foer att framstaella reproducerbara partiklar av definierad storlek
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
WO1993017668A1 (en) * 1992-03-12 1993-09-16 Alkermes Controlled Therapeutics, Inc. Controlled release acth containing microspheres
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
DK0644771T4 (da) * 1992-06-11 2006-12-27 Alkermes Inc Lægemiddelsystem til levering af erythropoietin
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
FR2705232A1 (fr) 1994-11-25
DE4416812C2 (de) 2003-02-06
TNSN94046A1 (fr) 1995-04-25
AT406017B (de) 2000-01-25
PT101518B (pt) 2000-12-29
ITMI940931A0 (it) 1994-05-11
IN182330B (enrdf_load_html_response) 1999-03-20
NO307403B1 (no) 2000-04-03
DK54994A (da) 1994-11-16
GR1002034B (en) 1995-10-31
LU88482A1 (fr) 1994-12-01
HU220617B1 (hu) 2002-03-28
NO941810D0 (no) 1994-05-13
DZ1779A1 (fr) 2002-02-17
FR2705232B1 (fr) 1995-08-25
HUT67599A (en) 1995-04-28
OA09939A (fr) 1994-11-15
CN1104557A (zh) 1995-07-05
DK171454B1 (da) 1996-11-04
ES2097083B1 (es) 1997-12-01
BR9401968A (pt) 1994-12-13
ZA943316B (en) 1995-01-16
CA2123481C (en) 2005-01-11
HU9401412D0 (en) 1994-08-29
SE9401557L (sv) 1994-11-16
PL175780B1 (pl) 1999-02-26
IE940392A1 (en) 1994-11-16
JPH072652A (ja) 1995-01-06
GB9409565D0 (en) 1994-07-06
RU2125869C1 (ru) 1999-02-10
NO941810L (no) 1994-11-16
ES2097083A1 (es) 1997-03-16
FI942222L (fi) 1994-11-16
CA2123481A1 (en) 1994-11-16
CN1050534C (zh) 2000-03-22
HK1002831A1 (en) 1998-09-18
NL9400795A (nl) 1994-12-01
SE519004C2 (sv) 2002-12-17
JP3139913B2 (ja) 2001-03-05
PT101518A (pt) 1995-03-01
MA23194A1 (fr) 1994-12-31
CH688572A5 (fr) 1997-11-28
FI942222A0 (fi) 1994-05-13
GB2277915B (en) 1997-10-29
NZ260520A (en) 1994-12-22
IT1269508B (it) 1997-04-01
DE4416812A1 (de) 1994-11-17
SE9401557D0 (sv) 1994-05-05
GB9310030D0 (en) 1993-06-30
AU685094B2 (en) 1998-01-15
AU6308494A (en) 1994-11-17
ATA98794A (de) 1999-06-15
BE1008323A3 (fr) 1996-04-02
ITMI940931A1 (it) 1995-11-11
SG46631A1 (en) 1998-02-20
GB2277915A (en) 1994-11-16
KR100341261B1 (ko) 2002-09-27

Similar Documents

Publication Publication Date Title
FI96278C (fi) Menetelmä mikrokapselin valmistamiseksi, josta vapautuu pidennetysti luteinisoivaa hormonia vapauttavaa hormonia
JP3600252B2 (ja) 医薬物質を持続的に制御して放出できる組成物
US6692770B2 (en) Starch microparticles
CN103703079B (zh) 核-壳微球
AU2001294458B2 (en) Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
JPH05178740A (ja) 徐放性組成物およびその製造方法
US5569467A (en) Process for the preparation of microballs and microballs thus obtained
FI112915B (fi) Menetelmä kuivakäsiteltyjen partikkelien valmistamiseksi
JPH0632732A (ja) 徐放性マイクロスフェア製剤の製造方法
PL212531B1 (pl) Kompozycja o przedluzonym uwalnianiu leuproreliny, sposób wytwarzania kompozycji, srodek farmaceutyczny zawierajacy kompozycje i zastosowanie kompozycji, sposób wytwarzania polimeru kwasu mlekowego i kwasu glikolowego i zastosowanie polimeru
AU2001294458A1 (en) Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
DE3782117T2 (de) Verkapselung von trh bzw. dessen analoga.
US7105181B2 (en) Microparticles
JP2867404B2 (ja) ドラッグデリバリーのための多孔性ミクロスフェアおよびその製造法
GB1573459A (en) Absorbable polymer drug compositions
JPH04124127A (ja) マイクロカプセル型徐放性製剤及びその製造法
JPH0372046B2 (enrdf_load_html_response)
JPS6341416A (ja) 鎮痛性ペプチド含有マイクロカプセルの製造法