FI111604B - Menetelmä suun kautta annettavien farmaseuttisten valmisteiden valmistamiseksi - Google Patents

Menetelmä suun kautta annettavien farmaseuttisten valmisteiden valmistamiseksi Download PDF

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Publication number
FI111604B
FI111604B FI925270A FI925270A FI111604B FI 111604 B FI111604 B FI 111604B FI 925270 A FI925270 A FI 925270A FI 925270 A FI925270 A FI 925270A FI 111604 B FI111604 B FI 111604B
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FI
Finland
Prior art keywords
group
formula
compound
process according
optionally substituted
Prior art date
Application number
FI925270A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI925270A (fi
FI925270A0 (fi
Inventor
Tadashi Makino
Yoshio Mizukami
Jun-Ichi Kikuta
Original Assignee
Takeda Chemical Industries Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17938952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI111604(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI925270A0 publication Critical patent/FI925270A0/fi
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FI925270A 1991-11-20 1992-11-19 Menetelmä suun kautta annettavien farmaseuttisten valmisteiden valmistamiseksi FI111604B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30492491 1991-11-20
JP30492491 1991-11-20

Publications (3)

Publication Number Publication Date
FI925270A0 FI925270A0 (fi) 1992-11-19
FI925270A FI925270A (fi) 1993-05-21
FI111604B true FI111604B (fi) 2003-08-29

Family

ID=17938952

Family Applications (2)

Application Number Title Priority Date Filing Date
FI925270A FI111604B (fi) 1991-11-20 1992-11-19 Menetelmä suun kautta annettavien farmaseuttisten valmisteiden valmistamiseksi
FI20030210A FI20030210A (fi) 1991-11-20 2003-02-12 Suun kautta annettavat farmaseuttiset valmisteet sekä menetelmä niiden valmistamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20030210A FI20030210A (fi) 1991-11-20 2003-02-12 Suun kautta annettavat farmaseuttiset valmisteet sekä menetelmä niiden valmistamiseksi

Country Status (18)

Country Link
US (1) US5534534A (nl)
EP (3) EP1468683A3 (nl)
KR (1) KR100256633B1 (nl)
CN (1) CN1047518C (nl)
AT (2) ATE277602T1 (nl)
AU (1) AU659691B2 (nl)
BR (1) BR1100336A (nl)
CA (1) CA2083305C (nl)
DE (2) DE69233424T2 (nl)
DK (1) DK0546358T3 (nl)
ES (1) ES2104797T3 (nl)
FI (2) FI111604B (nl)
GR (1) GR3025338T3 (nl)
HU (1) HU211608A9 (nl)
MX (1) MX9206634A (nl)
NO (1) NO304408B1 (nl)
NZ (1) NZ245175A (nl)
TW (1) TW284688B (nl)

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TW284688B (nl) * 1991-11-20 1996-09-01 Takeda Pharm Industry Co Ltd
TW272942B (nl) * 1993-02-10 1996-03-21 Takeda Pharm Industry Co Ltd
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EA200701442A1 (ru) * 2005-01-06 2008-02-28 Элан Фарма Интернэшнл Лтд. Композиции наночастиц кандесартана
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TW200800299A (en) * 2006-04-27 2008-01-01 Takeda Pharmaceutical Pharmaceutical composition
JP5361188B2 (ja) * 2006-08-10 2013-12-04 武田薬品工業株式会社 医薬組成物
WO2008045006A1 (en) * 2006-10-11 2008-04-17 Fako Ilaclari A. S. Formulations of candesartan
ES2301401B1 (es) * 2006-11-28 2009-06-08 Laboratorios Liconsa S.A. Composicion farmaceutica solida estabilizada de candesartan cilexetilo.
EP1952806A1 (en) 2007-02-01 2008-08-06 Helm AG Process for the preparation of adsorbates of candesartan
DE602008002371D1 (de) * 2007-03-08 2010-10-14 Teva Pharma Pharmazeutische zusammensetzung mit candesartan-cilexetil
ES2743784T3 (es) * 2007-03-28 2020-02-20 Takeda Pharmaceuticals Co Composición farmacéutica sólida que comprende un derivado de benzimidazol-7-carboxilato y un agente regulador del pH
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US9387249B2 (en) 2008-12-23 2016-07-12 Takeda Pharmaceutical Company Limited Methods of treating hypertension with at least one angiotensin II receptor blocker and chlorthalidone
ES2364011B1 (es) 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
EA022623B1 (ru) 2010-10-06 2016-02-29 ГЛАКСОСМИТКЛАЙН ЭлЭлСи Производные бензимидазола в качестве ингибиторов pi3-киназ
CN102138920A (zh) * 2011-02-24 2011-08-03 海南中济医药科技有限公司 一种含有坎地沙坦酯和氢氯噻嗪的药物组合物及其制备方法
CN102357095A (zh) * 2011-07-12 2012-02-22 迪沙药业集团有限公司 稳定的药物组合物
EA027324B1 (ru) 2011-11-11 2017-07-31 Пфайзер Инк. 2-тиопиримидиноны
WO2014088123A1 (en) * 2012-12-05 2014-06-12 Sawai Pharmaceutical Co., Ltd. Candesartan cilexetil-containing preparation
PL236001B1 (pl) 2012-12-21 2020-11-30 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję
CN105338982B (zh) 2013-04-25 2017-10-10 杏林制药株式会社 固体药用组合物
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WO2016136849A1 (ja) 2015-02-26 2016-09-01 武田薬品工業株式会社 固形製剤
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Also Published As

Publication number Publication date
HU211608A9 (en) 1995-12-28
EP0546358B1 (en) 1997-08-27
DE69221831T2 (de) 1998-01-02
DE69221831D1 (de) 1997-10-02
ATE157248T1 (de) 1997-09-15
CA2083305A1 (en) 1993-05-21
GR3025338T3 (en) 1998-02-27
EP0546358A3 (nl) 1994-03-30
AU2839192A (en) 1993-05-27
AU659691B2 (en) 1995-05-25
EP1468683A2 (en) 2004-10-20
CN1072338A (zh) 1993-05-26
BR1100336A (pt) 2000-04-18
EP0782852B1 (en) 2004-09-29
EP1468683A3 (en) 2012-06-06
FI925270A (fi) 1993-05-21
KR930009606A (ko) 1993-06-21
DE69233424T2 (de) 2005-02-17
NO924417L (no) 1993-05-21
ATE277602T1 (de) 2004-10-15
CA2083305C (en) 2003-12-09
CN1047518C (zh) 1999-12-22
KR100256633B1 (ko) 2000-05-15
NO924417D0 (no) 1992-11-16
MX9206634A (es) 1993-05-31
NZ245175A (en) 1994-07-26
TW284688B (nl) 1996-09-01
NO304408B1 (no) 1998-12-14
US5534534A (en) 1996-07-09
FI20030210A (fi) 2003-02-12
EP0546358A2 (en) 1993-06-16
ES2104797T3 (es) 1997-10-16
FI925270A0 (fi) 1992-11-19
DK0546358T3 (da) 1998-03-09
DE69233424D1 (de) 2004-11-04
EP0782852A1 (en) 1997-07-09

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