FI111384B - Menetelmä modifioidun selkärankaispoxviruksen molekylaariseksi kloonaamiseksi, modifioitu virus, sen DNA ja sen käyttö - Google Patents
Menetelmä modifioidun selkärankaispoxviruksen molekylaariseksi kloonaamiseksi, modifioitu virus, sen DNA ja sen käyttö Download PDFInfo
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- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
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- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
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- C12Y304/21—Serine endopeptidases (3.4.21)
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24041—Use of virus, viral particle or viral elements as a vector
- C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
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- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Communicable Diseases (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/750,080 US5445953A (en) | 1991-08-26 | 1991-08-26 | Direct molecular cloning of a modified poxvirus genome |
| US75008091 | 1991-08-26 | ||
| US91473892A | 1992-07-20 | 1992-07-20 | |
| US91473892 | 1992-07-20 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI923828A0 FI923828A0 (fi) | 1992-08-26 |
| FI923828A FI923828A (fi) | 1993-02-27 |
| FI111384B true FI111384B (fi) | 2003-07-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI923828A FI111384B (fi) | 1991-08-26 | 1992-08-26 | Menetelmä modifioidun selkärankaispoxviruksen molekylaariseksi kloonaamiseksi, modifioitu virus, sen DNA ja sen käyttö |
Country Status (17)
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| US (2) | US6265183B1 (ja) |
| EP (1) | EP0561034B1 (ja) |
| JP (1) | JPH06261763A (ja) |
| AT (1) | ATE181108T1 (ja) |
| AU (1) | AU652467B2 (ja) |
| BR (1) | BR9203322A (ja) |
| CA (1) | CA2076839C (ja) |
| CZ (1) | CZ264192A3 (ja) |
| DE (1) | DE69229390T2 (ja) |
| FI (1) | FI111384B (ja) |
| HU (1) | HU219369B (ja) |
| MX (1) | MX9204926A (ja) |
| NO (1) | NO310306B1 (ja) |
| PL (1) | PL295733A1 (ja) |
| SI (1) | SI9200190A (ja) |
| SK (1) | SK264192A3 (ja) |
| YU (1) | YU79092A (ja) |
Families Citing this family (32)
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| GB8927722D0 (en) * | 1989-12-07 | 1990-02-07 | British Bio Technology | Proteins and nucleic acids |
| EP0753581A1 (en) | 1995-07-10 | 1997-01-15 | Immuno Ag | Improved recombinant eukaryotic cytoplasmic viruses, method for their production and their use as vaccines |
| US20030138454A1 (en) * | 1997-06-09 | 2003-07-24 | Oxxon Pharmaccines, Ltd. | Vaccination method |
| GB9711957D0 (en) * | 1997-06-09 | 1997-08-06 | Isis Innovation | Methods and reagents for vaccination |
| WO2000073479A1 (en) * | 1999-05-28 | 2000-12-07 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector |
| US20040063653A1 (en) * | 2000-12-21 | 2004-04-01 | Shiver John W. | Polynucleotide vaccines expressing codon optimized hiv-1 pol and modified hiv-1 pol |
| CA2401974C (en) | 2000-03-02 | 2013-07-02 | Emory University | Dna expression vectors and methods of use |
| US20040105871A1 (en) * | 2000-03-02 | 2004-06-03 | Robinson Harriet L. | Compositions and methods for generating an immune response |
| US8623379B2 (en) * | 2000-03-02 | 2014-01-07 | Emory University | Compositions and methods for generating an immune response |
| DE60234018D1 (de) * | 2001-03-08 | 2009-11-26 | Univ Emory | Mva-exprimierende modifizierte hiv-envelope-, gag-, und pol-gene |
| US7223740B2 (en) | 2001-05-23 | 2007-05-29 | Fornix Biosciences N.V. | Vectors for enhanced expression of VEGF for atrial disease treatment |
| AU2002309335A1 (en) * | 2001-05-23 | 2002-12-03 | Fornix Biosciences N.V. | Vectors for enhanced expression of vegf for disease treatment |
| GB0118532D0 (en) * | 2001-07-30 | 2001-09-19 | Isis Innovation | Materials and methods relating to improved vaccination strategies |
| GB2382578A (en) * | 2001-11-30 | 2003-06-04 | Isis Innovation | Fowlpox-based vaccine |
| CN1596126A (zh) * | 2001-11-30 | 2005-03-16 | 埃西斯创新有限公司 | 疫苗 |
| CA2425021A1 (en) * | 2002-04-12 | 2003-10-12 | Sumitomo Electric Industries, Ltd. | Control of the ratio of lap to lip |
| CN101831411A (zh) * | 2002-05-16 | 2010-09-15 | 巴法里安诺迪克有限公司 | 表达插入痘病毒基因组中的同源基因的重组痘病毒 |
| GB0215621D0 (en) * | 2002-07-05 | 2002-08-14 | Imp College Innovations Ltd | Improved poxvirus vaccines |
| US20050175627A1 (en) * | 2003-09-24 | 2005-08-11 | Oxxon Therapeutics Ltd. | HIV pharmaccines |
| US20090098529A1 (en) * | 2006-10-16 | 2009-04-16 | Nanhai Chen | Methods for attenuating virus strains for diagnostic and therapeutic uses |
| US8202967B2 (en) | 2006-10-27 | 2012-06-19 | Boehringer Ingelheim Vetmedica, Inc. | H5 proteins, nucleic acid molecules and vectors encoding for those, and their medicinal use |
| GB201006405D0 (en) | 2010-04-16 | 2010-06-02 | Isis Innovation | Poxvirus expression system |
| AR083533A1 (es) | 2010-10-22 | 2013-03-06 | Boehringer Ingelheim Vetmed | Proteinas de hemaglutinina 5 (h5) para el tratamiento y prevencion de las infecciones de gripe |
| CN114262690A (zh) | 2011-04-15 | 2022-04-01 | 吉恩勒克斯公司 | 减毒的痘苗病毒的克隆毒株及其使用方法 |
| AR088028A1 (es) | 2011-08-15 | 2014-05-07 | Boehringer Ingelheim Vetmed | Proteinas h5, de h5n1 para un uso medicinal |
| US20140140959A1 (en) | 2012-10-05 | 2014-05-22 | Aladar A. Szalay | Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes |
| MX360137B (es) | 2013-02-21 | 2018-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Proteínas h5 del virus de la influenza h5n1 para usarse como un medicamento. |
| WO2015103438A2 (en) | 2014-01-02 | 2015-07-09 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| BR102015012334A2 (pt) * | 2015-05-27 | 2016-11-29 | Fundação Hemoct De Ribeirão Preto Fundherp | processo de produção do fator vii de coagulação sanguínea e fator vii de coagulação sanguínea |
| AU2017206102C1 (en) | 2016-01-08 | 2022-02-10 | Geovax Inc. | Compositions and methods for generating an immune response to a tumor associated antigen |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| WO2024011250A1 (en) | 2022-07-08 | 2024-01-11 | Viromissile, Inc. | Oncolytic vaccinia viruses and recombinant viruses and methods of use thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5174993A (en) | 1981-12-24 | 1992-12-29 | Health Research Inc. | Recombinant avipox virus and immunological use thereof |
| US5110587A (en) | 1981-12-24 | 1992-05-05 | Health Research, Incorporated | Immunogenic composition comprising synthetically modified vaccinia virus |
| US5505941A (en) | 1981-12-24 | 1996-04-09 | Health Research, Inc. | Recombinant avipox virus and method to induce an immune response |
| US5155020A (en) | 1989-03-08 | 1992-10-13 | Health Research Inc. | Recombinant poxvirus host range selection system |
| US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
| US5364773A (en) | 1991-03-07 | 1994-11-15 | Virogenetics Corporation | Genetically engineered vaccine strain |
| US5338683A (en) | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
| US5135855A (en) * | 1986-09-03 | 1992-08-04 | The United States Of America As Represented By The Department Of Health And Human Services | Rapid, versatile and simple system for expressing genes in eukaryotic cells |
| US5266313A (en) | 1987-02-03 | 1993-11-30 | The United States Of America As Represented By The Department Of Health And Human Services | Raccoon poxvirus as a gene expression and vaccine vector for genes of rabies virus and other organisms |
| FR2619314B1 (fr) * | 1987-08-11 | 1990-06-15 | Transgene Sa | Analogue du facteur viii, procede de preparation et composition pharmaceutique le contenant |
| AU625584B2 (en) | 1989-03-08 | 1992-07-16 | Health Research Inc. | Recombinant poxvirus host selection system |
| US5225336A (en) | 1989-03-08 | 1993-07-06 | Health Research Incorporated | Recombinant poxvirus host range selection system |
| HUT63459A (en) * | 1990-01-26 | 1993-08-30 | Immuno Ag | Blood factors produced by recommbinant process, process for expressing them, as well as recombinant vaccine viruses used in the process |
| US5204243A (en) | 1990-02-14 | 1993-04-20 | Health Research Incorporated | Recombinant poxvirus internal cores |
| DE69132311T2 (de) | 1990-09-25 | 2000-12-14 | Cantab Pharmaceuticals Research Ltd., Cambridge | Bei einer transkomplementenden zellinie erzeugter defektiver virenimpfstoff |
| US5863542A (en) | 1991-03-07 | 1999-01-26 | Virogenetics Corporation | Recombinant attenuated ALVAC canaryopox virus containing heterologous HIV or SIV inserts |
| US5997878A (en) | 1991-03-07 | 1999-12-07 | Connaught Laboratories | Recombinant poxvirus-cytomegalovirus, compositions and uses |
| JP3602530B2 (ja) | 1991-03-07 | 2004-12-15 | ヴァイロジェネティクス コーポレイション | 遺伝子操作したワクチン菌株 |
| US5989561A (en) | 1991-03-07 | 1999-11-23 | Virogenetics Corporation | Recombinant poxvirus-calicivirus rabbit hemorrhagic disease virus (RHDV) compositions and uses |
| US5843456A (en) | 1991-03-07 | 1998-12-01 | Virogenetics Corporation | Alvac poxvirus-rabies compositions and combination compositions and uses |
| US5626850A (en) | 1992-07-30 | 1997-05-06 | Akzo Nobel N.V. | Non-shedding live herpesvirus vaccine |
| EP1840209A3 (en) | 1995-01-13 | 2008-03-05 | Virogenetics Corporation | Adeno-associated virus vectors and use thereof |
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1992
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- 1992-08-11 DE DE69229390T patent/DE69229390T2/de not_active Expired - Lifetime
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- 1992-08-25 AU AU21269/92A patent/AU652467B2/en not_active Ceased
- 1992-08-25 HU HU9202737A patent/HU219369B/hu not_active IP Right Cessation
- 1992-08-25 CA CA002076839A patent/CA2076839C/en not_active Expired - Fee Related
- 1992-08-25 NO NO19923323A patent/NO310306B1/no not_active IP Right Cessation
- 1992-08-25 YU YU79092A patent/YU79092A/sh unknown
- 1992-08-26 SK SK2641-92A patent/SK264192A3/sk unknown
- 1992-08-26 CZ CS922641A patent/CZ264192A3/cs unknown
- 1992-08-26 MX MX9204926A patent/MX9204926A/es unknown
- 1992-08-26 PL PL29573392A patent/PL295733A1/xx unknown
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1994
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1996
- 1996-05-22 US US08/651,472 patent/US6103244A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| SK264192A3 (en) | 1995-08-09 |
| MX9204926A (es) | 1994-02-28 |
| NO923323L (no) | 1993-03-01 |
| EP0561034A3 (ja) | 1995-04-26 |
| CA2076839A1 (en) | 1993-02-27 |
| NO310306B1 (no) | 2001-06-18 |
| HU219369B (en) | 2001-03-28 |
| BR9203322A (pt) | 1993-03-30 |
| CZ264192A3 (en) | 1993-08-11 |
| US6265183B1 (en) | 2001-07-24 |
| EP0561034A2 (en) | 1993-09-22 |
| DE69229390D1 (de) | 1999-07-15 |
| EP0561034B1 (en) | 1999-06-09 |
| YU79092A (sh) | 1995-12-04 |
| AU652467B2 (en) | 1994-08-25 |
| ATE181108T1 (de) | 1999-06-15 |
| FI923828A0 (fi) | 1992-08-26 |
| CA2076839C (en) | 2007-06-12 |
| HUT69927A (en) | 1995-09-28 |
| NO923323D0 (no) | 1992-08-25 |
| AU2126992A (en) | 1993-03-04 |
| PL295733A1 (en) | 1993-05-17 |
| DE69229390T2 (de) | 1999-11-11 |
| US6103244A (en) | 2000-08-15 |
| JPH06261763A (ja) | 1994-09-20 |
| SI9200190A (en) | 1993-03-31 |
| FI923828A (fi) | 1993-02-27 |
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