FI107993B - Mikropartikkelien valmistus - Google Patents

Mikropartikkelien valmistus Download PDF

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Publication number
FI107993B
FI107993B FI940456A FI940456A FI107993B FI 107993 B FI107993 B FI 107993B FI 940456 A FI940456 A FI 940456A FI 940456 A FI940456 A FI 940456A FI 107993 B FI107993 B FI 107993B
Authority
FI
Finland
Prior art keywords
microcapsules
peg
starch
microspheres
oil
Prior art date
Application number
FI940456A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI940456A (fi
FI940456A0 (fi
Inventor
Lisbeth Illum
Olufunmiloyo Lilly Johnson
Original Assignee
West Pharm Serv Drug Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharm Serv Drug Res Ltd filed Critical West Pharm Serv Drug Res Ltd
Publication of FI940456A publication Critical patent/FI940456A/fi
Publication of FI940456A0 publication Critical patent/FI940456A0/fi
Application granted granted Critical
Publication of FI107993B publication Critical patent/FI107993B/fi

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225Microparticles, microcapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/12Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution
    • B01J13/125Making microcapsules or microballoons by phase separation removing solvent from the wall-forming material solution by evaporation of the solvent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acoustics & Sound (AREA)
  • Dispersion Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI940456A 1991-08-01 1994-01-31 Mikropartikkelien valmistus FI107993B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9116610 1991-08-01
GB919116610A GB9116610D0 (en) 1991-08-01 1991-08-01 Preparation of microparticles
GB9201421 1992-08-03
PCT/GB1992/001421 WO1993002712A1 (en) 1991-08-01 1992-08-03 Preparation of microparticles

Publications (3)

Publication Number Publication Date
FI940456A FI940456A (fi) 1994-01-31
FI940456A0 FI940456A0 (fi) 1994-01-31
FI107993B true FI107993B (fi) 2001-11-15

Family

ID=10699347

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940456A FI107993B (fi) 1991-08-01 1994-01-31 Mikropartikkelien valmistus

Country Status (14)

Country Link
US (1) US5648095A (ja)
EP (1) EP0596984B1 (ja)
JP (1) JP3604381B2 (ja)
AT (1) ATE186221T1 (ja)
AU (1) AU665206B2 (ja)
CA (1) CA2113901C (ja)
DE (1) DE69230254T2 (ja)
DK (1) DK0596984T3 (ja)
ES (1) ES2140415T3 (ja)
FI (1) FI107993B (ja)
GB (2) GB9116610D0 (ja)
GR (1) GR3032234T3 (ja)
NO (1) NO308448B1 (ja)
WO (1) WO1993002712A1 (ja)

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GB9400981D0 (en) 1994-04-13
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AU2376892A (en) 1993-03-02
DE69230254T2 (de) 2000-03-16
WO1993002712A1 (en) 1993-02-18
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EP0596984A1 (en) 1994-05-18
FI940456A (fi) 1994-01-31
NO308448B1 (no) 2000-09-18
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GB2273657A (en) 1994-06-29
US5648095A (en) 1997-07-15
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JPH06511423A (ja) 1994-12-22
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AU665206B2 (en) 1995-12-21
ATE186221T1 (de) 1999-11-15

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