FI104493B - Pichia pastoris-hiivan happaman fosfataasin geeni - Google Patents

Pichia pastoris-hiivan happaman fosfataasin geeni Download PDF

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Publication number
FI104493B
FI104493B FI915893A FI915893A FI104493B FI 104493 B FI104493 B FI 104493B FI 915893 A FI915893 A FI 915893A FI 915893 A FI915893 A FI 915893A FI 104493 B FI104493 B FI 104493B
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FI
Finland
Prior art keywords
seq
sequence
gene
dna
pichia pastoris
Prior art date
Application number
FI915893A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI915893A0 (fi
FI915893A (fi
Inventor
Richard G Buckholz
Original Assignee
Res Corp Technologies Inc
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Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Publication of FI915893A0 publication Critical patent/FI915893A0/fi
Publication of FI915893A publication Critical patent/FI915893A/fi
Application granted granted Critical
Publication of FI104493B publication Critical patent/FI104493B/fi

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/938—Pichia

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI915893A 1990-12-14 1991-12-13 Pichia pastoris-hiivan happaman fosfataasin geeni FI104493B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/627,539 US5268273A (en) 1990-12-14 1990-12-14 Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
US62753990 1990-12-14

Publications (3)

Publication Number Publication Date
FI915893A0 FI915893A0 (fi) 1991-12-13
FI915893A FI915893A (fi) 1992-06-15
FI104493B true FI104493B (fi) 2000-02-15

Family

ID=24515081

Family Applications (2)

Application Number Title Priority Date Filing Date
FI915893A FI104493B (fi) 1990-12-14 1991-12-13 Pichia pastoris-hiivan happaman fosfataasin geeni
FI992503A FI113474B (fi) 1990-12-14 1999-11-24 Pichia pastoris-hiivan happaman fosfataasin geenin DNA-kappale

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI992503A FI113474B (fi) 1990-12-14 1999-11-24 Pichia pastoris-hiivan happaman fosfataasin geenin DNA-kappale

Country Status (22)

Country Link
US (1) US5268273A (no)
EP (1) EP0495208B1 (no)
JP (1) JP3437850B2 (no)
KR (1) KR0181179B1 (no)
CN (1) CN1062169A (no)
AR (1) AR245218A1 (no)
AT (1) ATE208822T1 (no)
AU (1) AU637734B2 (no)
CA (1) CA2055542C (no)
CS (1) CS378891A3 (no)
DE (1) DE69132812T2 (no)
FI (2) FI104493B (no)
HU (1) HU913926D0 (no)
IE (1) IE914354A1 (no)
IL (1) IL100363A0 (no)
MX (1) MX9102546A (no)
NO (1) NO314151B1 (no)
PL (1) PL292765A1 (no)
PT (1) PT99802A (no)
TW (1) TW201330B (no)
YU (1) YU193591A (no)
ZA (1) ZA919776B (no)

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GB9307371D0 (en) * 1993-04-08 1993-06-02 Walls Alan J Fusion proteins
US5521086A (en) * 1993-09-16 1996-05-28 Cephalon, Inc. Secretion sequence for the production of a heterologous protein in yeast
IT1266740B1 (it) * 1994-07-01 1997-01-14 Maria Paola Landini Materiale proteico ricombinante legante anticorpi contro il citomegalovirus umano, reagenti diagnostici derivati da tale
CA2202351A1 (en) * 1994-10-18 1996-04-25 George Phillip Vlasuk Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
HU225126B1 (en) * 1994-10-18 2006-06-28 Dendreon Corp Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5863894A (en) * 1995-06-05 1999-01-26 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5866542A (en) * 1994-10-18 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
EP0877816A1 (en) * 1996-02-01 1998-11-18 North American Vaccine, Inc. Expression of group b neisseria meningitidis outer membrane (mb3) protein from yeast and vaccines
MX9605082A (es) 1996-10-24 1998-04-30 Univ Autonoma De Nuevo Leon Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
WO1999007862A1 (en) * 1997-08-05 1999-02-18 Chiron Corporation Novel pichia pastoris gene sequences and methods for their use
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
AU2614500A (en) * 1999-01-14 2000-08-01 Novozymes Biotech, Inc. Polypeptides having acid phosphatase activity and nucleic acids encoding same
ES2248067T3 (es) 1999-03-31 2006-03-16 Cornell Research Foundation, Inc. Fosfatasas con actividad de fitasa mejorada.
US6841370B1 (en) * 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
CN1320699A (zh) * 2000-04-27 2001-11-07 上海博德基因开发有限公司 一种新的多肽——人磷脂酶9和编码这种多肽的多核苷酸
CN1324948A (zh) * 2000-05-24 2001-12-05 上海博德基因开发有限公司 一种新的多肽——酸性磷酸酶14和编码这种多肽的多核苷酸
US6605450B1 (en) 2000-05-25 2003-08-12 Chiron Corporation Iron regulation of the PpSEC10 transcriptional regulatory region of Pichia pastoris and methods of use
CN1329020A (zh) * 2000-06-21 2002-01-02 上海博德基因开发有限公司 一种新的多肽——酸性磷酸酶家族蛋白11和编码这种多肽的多核苷酸
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
AU2002356880A1 (en) 2001-10-31 2003-05-12 Phytex, Llc Phytase-containing animal food and method
CA2498017C (en) * 2002-09-13 2016-06-14 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
JP2007519392A (ja) * 2003-07-30 2007-07-19 ザイモジェネティクス， インコーポレイテッド ピキアメタノリカ分泌シグナル
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
WO2008017066A2 (en) 2006-08-03 2008-02-07 Cornell Research Foundation, Inc. Phytases with improved thermal stability
US8097422B2 (en) 2007-06-20 2012-01-17 Salk Institute For Biological Studies Kir channel modulators
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
AU2009223846B2 (en) 2008-03-03 2014-11-20 Abbvie Inc. Methods for transforming yeast
US20090280103A1 (en) * 2008-04-04 2009-11-12 Martin Flueck Regulation of muscle repair
BRPI1011936A2 (pt) 2009-07-02 2016-05-03 Verdezyne Inc métodos biológicos para a preparação de ácido adípico
US20120184020A1 (en) * 2009-07-09 2012-07-19 Verdezyne, Inc. Engineered microorganisms with enhanced fermentation activity
US8889394B2 (en) * 2009-09-07 2014-11-18 Empire Technology Development Llc Multiple domain proteins
US8343752B2 (en) 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
WO2013006730A2 (en) 2011-07-06 2013-01-10 Verdezyne, Inc. Biological methods for preparing a fatty dicarboxylic acid
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HUE052914T2 (hu) 2012-12-19 2021-05-28 Corvay Bioproducts Gmbh Biológiai eljárások zsírdikarbonsav elõállítására
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DK3129493T3 (da) 2014-04-09 2021-09-27 Scripps Research Inst Import af unaturlige eller modificerede nukleosidtriphosphater ind i celler via nukleinsyre-triphosphat-transportører
CN104195059B (zh) * 2014-08-15 2016-08-24 陕西科技大学 多形汉逊酵母突变菌株及多形汉逊酵母生产d-阿拉伯糖醇的方法
US20180148744A1 (en) 2015-03-20 2018-05-31 Verdezyne, Inc. Biological methods for preparing 3-hydroxypropionic acid
EP3568408A4 (en) 2017-01-13 2020-12-16 Bolt Threads, Inc. ELASTOMER PROTEINS
CA3069321A1 (en) 2017-07-11 2019-01-17 Synthorx, Inc. Incorporation of unnatural nucleotides and methods thereof
CA3069697A1 (en) 2017-07-13 2019-01-17 Radici Chimica S.P.A. Biological methods for modifying cellular carbon flux
AU2018309166B2 (en) 2017-08-03 2022-12-08 Synthorx, Inc. Cytokine conjugates for the treatment of proliferative and infectious diseases
WO2020060948A1 (en) 2018-09-17 2020-03-26 Levadura Biotechnology, Inc. Production of cannabinoids in yeast using a fatty acid feedstock
SG11202107354WA (en) 2019-02-06 2021-08-30 Synthorx Inc Il-2 conjugates and methods of use thereof

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US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
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Also Published As

Publication number Publication date
FI19992503A (fi) 1999-11-24
ZA919776B (en) 1992-09-30
AR245218A1 (es) 1993-12-30
AU637734B2 (en) 1993-06-03
NO914935L (no) 1992-06-15
KR920012442A (ko) 1992-07-27
PL292765A1 (en) 1992-08-24
FI915893A0 (fi) 1991-12-13
TW201330B (no) 1993-03-01
NO914935D0 (no) 1991-12-13
MX9102546A (es) 1992-07-01
CA2055542A1 (en) 1992-06-15
NO314151B1 (no) 2003-02-03
FI113474B (fi) 2004-04-30
CA2055542C (en) 1999-08-31
AU8882391A (en) 1992-06-25
EP0495208B1 (en) 2001-11-14
KR0181179B1 (ko) 1999-04-01
IE914354A1 (en) 1992-06-17
JPH0576371A (ja) 1993-03-30
YU193591A (sh) 1994-06-10
IL100363A0 (en) 1992-09-06
EP0495208A3 (en) 1994-05-18
US5268273A (en) 1993-12-07
FI915893A (fi) 1992-06-15
EP0495208A2 (en) 1992-07-22
JP3437850B2 (ja) 2003-08-18
CS378891A3 (en) 1992-06-17
CN1062169A (zh) 1992-06-24
PT99802A (pt) 1992-12-31
ATE208822T1 (de) 2001-11-15
DE69132812D1 (de) 2001-12-20
HU913926D0 (en) 1992-02-28
DE69132812T2 (de) 2002-06-20

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Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC.