FI102176B1 - Menetelmä taksolien valmistamiseksi ja menetelmässä käytetyt välituotteet - Google Patents

Menetelmä taksolien valmistamiseksi ja menetelmässä käytetyt välituotteet

Info

Publication number
FI102176B1
FI102176B1 FI902660A FI902660A FI102176B1 FI 102176 B1 FI102176 B1 FI 102176B1 FI 902660 A FI902660 A FI 902660A FI 902660 A FI902660 A FI 902660A FI 102176 B1 FI102176 B1 FI 102176B1
Authority
FI
Finland
Prior art keywords
preparation
alkyl
taxol
taxols
aryl
Prior art date
Application number
FI902660A
Other languages
English (en)
Swedish (sv)
Other versions
FI102176B (fi
FI902660A0 (fi
Inventor
Robert A Holton
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State filed Critical Univ Florida State
Publication of FI902660A0 publication Critical patent/FI902660A0/fi
Priority claimed from DD341149A external-priority patent/DD300428A5/de
Priority to US07/949,345 priority Critical patent/US5262724A/en
Application granted granted Critical
Publication of FI102176B1 publication Critical patent/FI102176B1/fi
Publication of FI102176B publication Critical patent/FI102176B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FI902660A 1989-05-31 1990-05-29 Menetelmä taksolien valmistamiseksi ja menetelmässä käytetyt välituott eet FI102176B (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US07/949,345 US5262724A (en) 1990-05-29 1992-09-22 Examination method and apparatus

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US35963489A 1989-05-31 1989-05-31
US35963489 1989-05-31
US07/415,028 US5175315A (en) 1989-05-31 1989-09-29 Method for preparation of taxol using β-lactam
US41502889 1989-09-29
DD341149A DD300428A5 (de) 1989-05-31 1990-05-30 Verfahren zur herstellung von taxol
DD34114990 1990-05-30

Publications (3)

Publication Number Publication Date
FI902660A0 FI902660A0 (fi) 1990-05-29
FI102176B1 true FI102176B1 (fi) 1998-10-30
FI102176B FI102176B (fi) 1998-10-30

Family

ID=27179947

Family Applications (1)

Application Number Title Priority Date Filing Date
FI902660A FI102176B (fi) 1989-05-31 1990-05-29 Menetelmä taksolien valmistamiseksi ja menetelmässä käytetyt välituott eet

Country Status (28)

Country Link
US (1) US5175315A (fi)
EP (1) EP0400971B1 (fi)
JP (2) JPH0830050B2 (fi)
KR (1) KR0130387B1 (fi)
CN (2) CN1057082C (fi)
AT (1) ATE168997T1 (fi)
AU (1) AU630696B2 (fi)
BG (1) BG61074B2 (fi)
CA (2) CA2016951C (fi)
DE (1) DE69032512T2 (fi)
DK (1) DK0400971T3 (fi)
EG (1) EG19555A (fi)
ES (1) ES2122957T3 (fi)
FI (1) FI102176B (fi)
HU (1) HU208003B (fi)
IE (1) IE62678B1 (fi)
IL (1) IL94426A (fi)
MX (1) MX9203429A (fi)
NO (1) NO174099C (fi)
NZ (1) NZ233663A (fi)
OA (1) OA09740A (fi)
PL (2) PL163946B1 (fi)
PT (1) PT94187B (fi)
RO (1) RO111766B1 (fi)
RU (1) RU2097374C1 (fi)
SG (1) SG43234A1 (fi)
YU (1) YU97590A (fi)
ZA (1) ZA903809B (fi)

Families Citing this family (152)

* Cited by examiner, † Cited by third party
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US6335362B1 (en) * 1991-09-23 2002-01-01 Florida State University Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them
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HU208003B (en) 1993-07-28
DE69032512D1 (de) 1998-09-03
ZA903809B (en) 1991-03-27
IL94426A0 (en) 1991-03-10
HUT57199A (en) 1991-11-28
JP2500198B2 (ja) 1996-05-29
DE69032512T2 (de) 1999-03-25
RU2097374C1 (ru) 1997-11-27
AU5515090A (en) 1990-12-20
DK0400971T3 (da) 1999-04-26
PT94187A (pt) 1991-02-08
MX9203429A (es) 1992-07-01
CA2016951A1 (en) 1990-11-30
EP0400971A3 (en) 1992-01-02
FI102176B (fi) 1998-10-30
US5175315A (en) 1992-12-29
IE62678B1 (en) 1995-02-22
SG43234A1 (en) 1997-10-17
CN1086512A (zh) 1994-05-11
KR0130387B1 (ko) 1998-04-09
ES2122957T3 (es) 1999-01-01
EG19555A (en) 1995-09-30
NO174099B (no) 1993-12-06
BG61074B2 (bg) 1996-10-31
AU630696B2 (en) 1992-11-05
JPH0770057A (ja) 1995-03-14
IE901707L (en) 1990-11-30
ATE168997T1 (de) 1998-08-15
NO174099C (no) 1994-03-16
YU97590A (en) 1991-10-31
CA2214051A1 (en) 1990-11-30
JPH0386860A (ja) 1991-04-11
IL94426A (en) 1998-06-15
PL163946B1 (pl) 1994-05-31
PL285404A1 (en) 1991-02-11
CA2214051C (en) 2001-09-25
JPH0830050B2 (ja) 1996-03-27
FI902660A0 (fi) 1990-05-29
OA09740A (en) 1993-11-30
CN1064958C (zh) 2001-04-25
HU903245D0 (en) 1990-10-28
EP0400971A2 (en) 1990-12-05
NZ233663A (en) 1992-09-25
CN1057082C (zh) 2000-10-04
CN1057049A (zh) 1991-12-18
NO902404L (no) 1990-12-03
EP0400971B1 (en) 1998-07-29
NO902404D0 (no) 1990-05-30
PL164539B1 (pl) 1994-08-31
CA2016951C (en) 1998-05-12
RO111766B1 (ro) 1997-01-30
PT94187B (pt) 1996-08-30

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