PT95473A - Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem

Info

Publication number
PT95473A
PT95473A PT95473A PT9547390A PT95473A PT 95473 A PT95473 A PT 95473A PT 95473 A PT95473 A PT 95473A PT 9547390 A PT9547390 A PT 9547390A PT 95473 A PT95473 A PT 95473A
Authority
PT
Portugal
Prior art keywords
carbon atoms
homo
vitamin
derivatives
preparation
Prior art date
Application number
PT95473A
Other languages
English (en)
Other versions
PT95473B (pt
Inventor
Gerald Dr Kirsch
Guenter Dr Neef
Katica Schwarz
Matthias Dr Braeutigam
Ruth Dr Thieroff-Eckerdt
Petra Rach
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PT95473A publication Critical patent/PT95473A/pt
Publication of PT95473B publication Critical patent/PT95473B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
PT95473A 1989-10-02 1990-10-01 Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem PT95473B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3933034A DE3933034A1 (de) 1989-10-02 1989-10-02 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
PT95473A true PT95473A (pt) 1991-06-25
PT95473B PT95473B (pt) 1997-07-31

Family

ID=6390762

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95473A PT95473B (pt) 1989-10-02 1990-10-01 Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem

Country Status (18)

Country Link
US (1) US5665716A (pt)
EP (1) EP0421561B1 (pt)
JP (1) JPH03246273A (pt)
CN (2) CN1031705C (pt)
AT (1) ATE103893T1 (pt)
AU (1) AU639717B2 (pt)
CA (1) CA2026671C (pt)
DD (1) DD299178A5 (pt)
DE (2) DE3933034A1 (pt)
DK (1) DK0421561T3 (pt)
ES (1) ES2052166T3 (pt)
FI (1) FI93643C (pt)
HU (1) HU210032B (pt)
IE (1) IE71227B1 (pt)
IL (1) IL95872A (pt)
NO (1) NO178923C (pt)
PT (1) PT95473B (pt)
ZA (1) ZA907876B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
DE4200783C2 (de) * 1992-01-10 1997-02-06 Schering Ag (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
DE4328217C2 (de) * 1993-08-21 1996-01-11 Lohmann Therapie Syst Lts Therapeutisches System zur Behandlung der Psoriasis
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US5939408A (en) 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US20030129194A1 (en) * 1997-02-13 2003-07-10 Bone Care International, Inc. Targeted therapeutic delivery of vitamin D compounds
DE19935771A1 (de) 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP2004504295A (ja) * 2000-07-18 2004-02-12 ボーン　ケア　インターナショナル　インコーポレイテッド 安定化１α−ヒドロキシビタミンＤ
DE10156596A1 (de) * 2001-11-13 2003-05-28 Schering Ag Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP2005514929A (ja) * 2002-01-10 2005-05-26 テバ ファーマシューティカル インダストリーズ リミティド エピマービタミンｄ類似物の酵素による選択的なエステル化及び加溶媒分解及びエピマーの分離
WO2003106412A1 (en) * 2002-06-13 2003-12-24 Teva Pharmaceutical Industries Ltd. Epimerization of analogs of vitamin d
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
BRPI0715636A2 (pt) * 2006-08-29 2013-07-02 Teva Pharma composiÇÕes farmacologicamente ativas estÁveis incluindo compostos contendo vitamina d e corticosteràide com compatibilidade para ph baixo
US8716334B2 (en) * 2008-06-17 2014-05-06 Ben Gurion University Of The Negev Research And Development Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
AU2010208323B2 (en) 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (en) 2009-08-14 2019-05-22 Berg LLC Vitamin d3 and analogs thereof for treating alopecia
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
US10548908B2 (en) 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002078A1 (en) * 1984-10-04 1986-04-10 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
EP0245524B1 (en) * 1985-11-21 1991-04-17 Taisho Pharmaceutical Co. Ltd Vitamin d 3 derivative
US4847012A (en) * 1988-04-29 1989-07-11 Wisconsin Alumni Research Foundation Vitamin D related compounds and processes for their preparation
US4927815A (en) * 1988-04-29 1990-05-22 Wisconsin Alumni Research Foundation Compounds effective in inducing cell differentiation and process for preparing same
US5030772A (en) * 1990-02-14 1991-07-09 Deluca Hector F Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) * 1990-02-14 1993-11-09 Wisconsin Alumni Research Foundation Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Also Published As

Publication number Publication date
NO178923C (no) 1996-07-03
AU639717B2 (en) 1993-08-05
EP0421561A2 (de) 1991-04-10
FI93643C (fi) 1995-05-10
ES2052166T3 (es) 1994-07-01
PT95473B (pt) 1997-07-31
CN1106666A (zh) 1995-08-16
HUT55751A (en) 1991-06-28
DD299178A5 (de) 1992-04-02
IE71227B1 (en) 1997-02-12
IL95872A (en) 1995-03-15
DE59005254D1 (de) 1994-05-11
NO904269D0 (no) 1990-10-01
US5665716A (en) 1997-09-09
DK0421561T3 (da) 1994-07-25
IE903520A1 (en) 1991-04-10
HU906284D0 (en) 1991-03-28
ZA907876B (en) 1992-04-29
EP0421561B1 (de) 1994-04-06
DE3933034A1 (de) 1991-04-11
JPH03246273A (ja) 1991-11-01
NO904269L (no) 1991-04-03
FI904850A0 (fi) 1990-10-02
CA2026671C (en) 1998-12-08
ATE103893T1 (de) 1994-04-15
CN1031705C (zh) 1996-05-01
FI93643B (fi) 1995-01-31
CA2026671A1 (en) 1991-04-03
HU210032B (en) 1995-01-30
NO178923B (no) 1996-03-25
CN1053103C (zh) 2000-06-07
AU6371590A (en) 1991-04-11
CN1051907A (zh) 1991-06-05
EP0421561A3 (en) 1991-06-12
IL95872A0 (en) 1991-07-18

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910211

FG3A Patent granted, date of granting

Effective date: 19970506

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20011130