PT95473A - Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT95473A PT95473A PT95473A PT9547390A PT95473A PT 95473 A PT95473 A PT 95473A PT 95473 A PT95473 A PT 95473A PT 9547390 A PT9547390 A PT 9547390A PT 95473 A PT95473 A PT 95473A
- Authority
- PT
- Portugal
- Prior art keywords
- carbon atoms
- homo
- vitamin
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3933034A DE3933034A1 (de) | 1989-10-02 | 1989-10-02 | 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
PT95473A true PT95473A (pt) | 1991-06-25 |
PT95473B PT95473B (pt) | 1997-07-31 |
Family
ID=6390762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95473A PT95473B (pt) | 1989-10-02 | 1990-10-01 | Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem |
Country Status (18)
Country | Link |
---|---|
US (1) | US5665716A (pt) |
EP (1) | EP0421561B1 (pt) |
JP (1) | JPH03246273A (pt) |
CN (2) | CN1031705C (pt) |
AT (1) | ATE103893T1 (pt) |
AU (1) | AU639717B2 (pt) |
CA (1) | CA2026671C (pt) |
DD (1) | DD299178A5 (pt) |
DE (2) | DE3933034A1 (pt) |
DK (1) | DK0421561T3 (pt) |
ES (1) | ES2052166T3 (pt) |
FI (1) | FI93643C (pt) |
HU (1) | HU210032B (pt) |
IE (1) | IE71227B1 (pt) |
IL (1) | IL95872A (pt) |
NO (1) | NO178923C (pt) |
PT (1) | PT95473B (pt) |
ZA (1) | ZA907876B (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
US5030772A (en) * | 1990-02-14 | 1991-07-09 | Deluca Hector F | Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives |
US20040009958A1 (en) * | 1991-01-08 | 2004-01-15 | Bone Care International, Inc. | Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2 |
DE4200783C2 (de) * | 1992-01-10 | 1997-02-06 | Schering Ag | (5Z,7E,22E)-(1S,3R,24S)-24-Benzyl-9,10-secochola-5,7,10(19),22-tetraen-1,3,24-triol, Verfahren zur Herstellung und Pharmazeutische Präparate |
IL107185A (en) * | 1992-10-06 | 1998-02-22 | Schering Ag | History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them |
DE4328217C2 (de) * | 1993-08-21 | 1996-01-11 | Lohmann Therapie Syst Lts | Therapeutisches System zur Behandlung der Psoriasis |
US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
DE19619036A1 (de) | 1996-04-30 | 1997-11-13 | Schering Ag | Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
US5939408A (en) | 1996-05-23 | 1999-08-17 | Hoffman-La Roche Inc. | Vitamin D3 analogs |
US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
US20030129194A1 (en) * | 1997-02-13 | 2003-07-10 | Bone Care International, Inc. | Targeted therapeutic delivery of vitamin D compounds |
DE19935771A1 (de) | 1999-07-23 | 2001-02-01 | Schering Ag | Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
JP2004504295A (ja) * | 2000-07-18 | 2004-02-12 | ボーン ケア インターナショナル インコーポレイテッド | 安定化1α−ヒドロキシビタミンD |
DE10156596A1 (de) * | 2001-11-13 | 2003-05-28 | Schering Ag | Vitamin D-Derivate mit Acyloxygruppen in der Seitenkette, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln |
JP2005514929A (ja) * | 2002-01-10 | 2005-05-26 | テバ ファーマシューティカル インダストリーズ リミティド | エピマービタミンd類似物の酵素による選択的なエステル化及び加溶媒分解及びエピマーの分離 |
WO2003106412A1 (en) * | 2002-06-13 | 2003-12-24 | Teva Pharmaceutical Industries Ltd. | Epimerization of analogs of vitamin d |
US7094775B2 (en) | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
BRPI0715636A2 (pt) * | 2006-08-29 | 2013-07-02 | Teva Pharma | composiÇÕes farmacologicamente ativas estÁveis incluindo compostos contendo vitamina d e corticosteràide com compatibilidade para ph baixo |
US8716334B2 (en) * | 2008-06-17 | 2014-05-06 | Ben Gurion University Of The Negev Research And Development Authority | Substituted cyclohexylidene-ethylidene-octahydro-indene compounds |
AU2010208323B2 (en) | 2009-01-27 | 2016-03-10 | Berg Llc | Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy |
EP2464357B1 (en) | 2009-08-14 | 2019-05-22 | Berg LLC | Vitamin d3 and analogs thereof for treating alopecia |
KR20160013201A (ko) | 2013-05-29 | 2016-02-03 | 버그 엘엘씨 | 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화 |
US10548908B2 (en) | 2016-09-15 | 2020-02-04 | Nostopharma, LLC | Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986002078A1 (en) * | 1984-10-04 | 1986-04-10 | Wisconsin Alumni Research Foundation | Vitamin d derivatives and methods for preparing same |
EP0245524B1 (en) * | 1985-11-21 | 1991-04-17 | Taisho Pharmaceutical Co. Ltd | Vitamin d 3 derivative |
US4847012A (en) * | 1988-04-29 | 1989-07-11 | Wisconsin Alumni Research Foundation | Vitamin D related compounds and processes for their preparation |
US4927815A (en) * | 1988-04-29 | 1990-05-22 | Wisconsin Alumni Research Foundation | Compounds effective in inducing cell differentiation and process for preparing same |
US5030772A (en) * | 1990-02-14 | 1991-07-09 | Deluca Hector F | Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives |
US5260290A (en) * | 1990-02-14 | 1993-11-09 | Wisconsin Alumni Research Foundation | Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives |
-
1989
- 1989-10-02 DE DE3933034A patent/DE3933034A1/de not_active Withdrawn
-
1990
- 1990-10-01 DE DE90250249T patent/DE59005254D1/de not_active Expired - Lifetime
- 1990-10-01 PT PT95473A patent/PT95473B/pt not_active IP Right Cessation
- 1990-10-01 HU HU906284A patent/HU210032B/hu not_active IP Right Cessation
- 1990-10-01 AT AT90250249T patent/ATE103893T1/de not_active IP Right Cessation
- 1990-10-01 DK DK90250249.1T patent/DK0421561T3/da active
- 1990-10-01 DD DD90344338A patent/DD299178A5/de not_active IP Right Cessation
- 1990-10-01 NO NO904269A patent/NO178923C/no not_active IP Right Cessation
- 1990-10-01 ES ES90250249T patent/ES2052166T3/es not_active Expired - Lifetime
- 1990-10-01 EP EP90250249A patent/EP0421561B1/de not_active Expired - Lifetime
- 1990-10-01 CN CN90108993A patent/CN1031705C/zh not_active Expired - Fee Related
- 1990-10-02 ZA ZA907876A patent/ZA907876B/xx unknown
- 1990-10-02 IL IL9587290A patent/IL95872A/en not_active IP Right Cessation
- 1990-10-02 JP JP2263263A patent/JPH03246273A/ja active Pending
- 1990-10-02 CA CA002026671A patent/CA2026671C/en not_active Expired - Fee Related
- 1990-10-02 FI FI904850A patent/FI93643C/fi not_active IP Right Cessation
- 1990-10-02 US US07/592,017 patent/US5665716A/en not_active Expired - Fee Related
- 1990-10-02 AU AU63715/90A patent/AU639717B2/en not_active Ceased
- 1990-10-02 IE IE352090A patent/IE71227B1/en not_active IP Right Cessation
-
1994
- 1994-08-18 CN CN94115050A patent/CN1053103C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO178923C (no) | 1996-07-03 |
AU639717B2 (en) | 1993-08-05 |
EP0421561A2 (de) | 1991-04-10 |
FI93643C (fi) | 1995-05-10 |
ES2052166T3 (es) | 1994-07-01 |
PT95473B (pt) | 1997-07-31 |
CN1106666A (zh) | 1995-08-16 |
HUT55751A (en) | 1991-06-28 |
DD299178A5 (de) | 1992-04-02 |
IE71227B1 (en) | 1997-02-12 |
IL95872A (en) | 1995-03-15 |
DE59005254D1 (de) | 1994-05-11 |
NO904269D0 (no) | 1990-10-01 |
US5665716A (en) | 1997-09-09 |
DK0421561T3 (da) | 1994-07-25 |
IE903520A1 (en) | 1991-04-10 |
HU906284D0 (en) | 1991-03-28 |
ZA907876B (en) | 1992-04-29 |
EP0421561B1 (de) | 1994-04-06 |
DE3933034A1 (de) | 1991-04-11 |
JPH03246273A (ja) | 1991-11-01 |
NO904269L (no) | 1991-04-03 |
FI904850A0 (fi) | 1990-10-02 |
CA2026671C (en) | 1998-12-08 |
ATE103893T1 (de) | 1994-04-15 |
CN1031705C (zh) | 1996-05-01 |
FI93643B (fi) | 1995-01-31 |
CA2026671A1 (en) | 1991-04-03 |
HU210032B (en) | 1995-01-30 |
NO178923B (no) | 1996-03-25 |
CN1053103C (zh) | 2000-06-07 |
AU6371590A (en) | 1991-04-11 |
CN1051907A (zh) | 1991-06-05 |
EP0421561A3 (en) | 1991-06-12 |
IL95872A0 (en) | 1991-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19910211 |
|
FG3A | Patent granted, date of granting |
Effective date: 19970506 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20011130 |