ATE48993T1 - Aetheroxidderivate von zyklopropylphenolen. - Google Patents

Aetheroxidderivate von zyklopropylphenolen.

Info

Publication number
ATE48993T1
ATE48993T1 AT85401357T AT85401357T ATE48993T1 AT E48993 T1 ATE48993 T1 AT E48993T1 AT 85401357 T AT85401357 T AT 85401357T AT 85401357 T AT85401357 T AT 85401357T AT E48993 T1 ATE48993 T1 AT E48993T1
Authority
AT
Austria
Prior art keywords
cyclopropylphenols
aetheroxide
derivatives
relates
imidazolines
Prior art date
Application number
AT85401357T
Other languages
English (en)
Inventor
Henri Najer
Francois Giudicelli
Jean-Claude Dufour
Original Assignee
Henri Najer
Francois Giudicelli
Dufour J C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henri Najer, Francois Giudicelli, Dufour J C filed Critical Henri Najer
Application granted granted Critical
Publication of ATE48993T1 publication Critical patent/ATE48993T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/045Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C07C39/17Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings containing other rings in addition to the six-membered aromatic rings, e.g. cyclohexylphenol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24Halogenated derivatives
    • C07C39/42Halogenated derivatives containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT85401357T 1984-07-13 1985-07-04 Aetheroxidderivate von zyklopropylphenolen. ATE48993T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8411271A FR2567514B1 (fr) 1984-07-13 1984-07-13 Nouveaux ether-oxydes derives de cyclopropylphenols
EP85401357A EP0173597B1 (de) 1984-07-13 1985-07-04 Ätheroxidderivate von Zyklopropylphenolen

Publications (1)

Publication Number Publication Date
ATE48993T1 true ATE48993T1 (de) 1990-01-15

Family

ID=9306177

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85401357T ATE48993T1 (de) 1984-07-13 1985-07-04 Aetheroxidderivate von zyklopropylphenolen.

Country Status (11)

Country Link
US (1) US4663340A (de)
EP (1) EP0173597B1 (de)
JP (1) JPS6140268A (de)
KR (1) KR860001073A (de)
AT (1) ATE48993T1 (de)
AU (1) AU569013B2 (de)
CA (1) CA1247111A (de)
DE (1) DE3574969D1 (de)
DK (1) DK320485A (de)
FR (1) FR2567514B1 (de)
ZA (1) ZA855156B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4096363B2 (ja) * 1997-03-14 2008-06-04 日本新薬株式会社 鼻又は眼の充血治療剤
GB0409921D0 (en) * 2004-05-04 2004-06-09 Novartis Ag Organic compounds
US12246013B2 (en) 2008-08-01 2025-03-11 Eye Therapies Llc Vasoconstriction compositions and methods of use
US20100202979A1 (en) * 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of pulmonary diseases and conditions
US20100197694A1 (en) * 2008-08-01 2010-08-05 Gerald Horn Compositions and methods for treatment of diseases and conditions with increased vascular permeability
US20100203165A1 (en) 2008-08-01 2010-08-12 Gerald Horn Compositions and methods for treatment of disorders or conditions of the eye
US20110003823A1 (en) * 2008-08-01 2011-01-06 Alpha Synergy Development, Inc. Compositions and methods for treatment of diseases and conditions associated with vasodilation and/or vascular leakage
US8952011B2 (en) 2008-08-01 2015-02-10 Eye Therapies Llc Compositions and methods for the treatment of nasal conditions
CA2732521C (en) 2008-08-01 2017-11-07 Alpha Synergy Development, Inc. Vasoconstriction compositions and methods of use
US8987270B2 (en) 2009-07-27 2015-03-24 Eye Therapies Llc Formulations of selective alpha-2 agonists and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2149473A (en) * 1934-07-31 1939-03-07 Soc Of Chemical Ind Imidazolines
US2915431A (en) * 1956-07-17 1959-12-01 Lab Robert & Carriere Sa Des 2-(2'-isopropyl-4'-chloro-5'-methyl)-phenoxymethyl-2-imidazoline and its pharmaceutical uses
US3449355A (en) * 1967-04-04 1969-06-10 Dow Chemical Co 2-((3,4-dihalophenoxy)methyl)-2-imidazoline
FR2394531A1 (fr) * 1977-06-13 1979-01-12 Synthelabo Preparation de derives d'imidazoline

Also Published As

Publication number Publication date
DK320485D0 (da) 1985-07-12
AU4478485A (en) 1986-01-16
DK320485A (da) 1986-01-14
ZA855156B (en) 1986-02-26
CA1247111A (en) 1988-12-20
EP0173597A1 (de) 1986-03-05
FR2567514B1 (fr) 1987-08-28
FR2567514A1 (fr) 1986-01-17
JPS6140268A (ja) 1986-02-26
EP0173597B1 (de) 1989-12-27
KR860001073A (ko) 1986-02-22
US4663340A (en) 1987-05-05
DE3574969D1 (de) 1990-02-01
AU569013B2 (en) 1988-01-14

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