ES8601170A1 - Procedimiento para la preparacion de nuevos derivados tiazolidinicos - Google Patents
Procedimiento para la preparacion de nuevos derivados tiazolidinicosInfo
- Publication number
- ES8601170A1 ES8601170A1 ES530738A ES530738A ES8601170A1 ES 8601170 A1 ES8601170 A1 ES 8601170A1 ES 530738 A ES530738 A ES 530738A ES 530738 A ES530738 A ES 530738A ES 8601170 A1 ES8601170 A1 ES 8601170A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- thiazolidine derivatives
- preparation
- pharmaceutical compositions
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003548 thiazolidines Chemical class 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KKFDJZZADQONDE-UHFFFAOYSA-N (hydridonitrato)hydroxidocarbon(.) Chemical class O[C]=N KKFDJZZADQONDE-UHFFFAOYSA-N 0.000 abstract 1
- OGYGFUAIIOPWQD-UHFFFAOYSA-N 1,3-thiazolidine Chemical class C1CSCN1 OGYGFUAIIOPWQD-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU83888A HU188852B (en) | 1983-03-16 | 1983-03-16 | Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8601170A1 true ES8601170A1 (es) | 1985-11-01 |
| ES530738A0 ES530738A0 (es) | 1985-11-01 |
Family
ID=10951891
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES530738A Granted ES530738A0 (es) | 1983-03-16 | 1984-03-16 | Procedimiento para la preparacion de nuevos derivados tiazolidinicos |
| ES544286A Expired ES8604179A1 (es) | 1983-03-16 | 1985-06-17 | Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES544286A Expired ES8604179A1 (es) | 1983-03-16 | 1985-06-17 | Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US4616025A (enExample) |
| JP (1) | JPS59196877A (enExample) |
| KR (1) | KR840008001A (enExample) |
| AT (1) | AT383596B (enExample) |
| AU (1) | AU559753B2 (enExample) |
| BE (1) | BE899132A (enExample) |
| CA (1) | CA1273933A (enExample) |
| CH (1) | CH660592A5 (enExample) |
| CS (1) | CS241074B2 (enExample) |
| DD (1) | DD216929A5 (enExample) |
| DE (1) | DE3409801A1 (enExample) |
| DK (1) | DK143284A (enExample) |
| ES (2) | ES530738A0 (enExample) |
| FI (1) | FI79843C (enExample) |
| FR (1) | FR2542740B1 (enExample) |
| GB (1) | GB2140412B (enExample) |
| GR (1) | GR81883B (enExample) |
| HU (1) | HU188852B (enExample) |
| IE (1) | IE57101B1 (enExample) |
| IL (1) | IL71249A (enExample) |
| IN (1) | IN157738B (enExample) |
| IT (1) | IT1196048B (enExample) |
| LU (1) | LU85248A1 (enExample) |
| NL (1) | NL8400817A (enExample) |
| NO (1) | NO162858C (enExample) |
| NZ (1) | NZ207516A (enExample) |
| PL (2) | PL142909B1 (enExample) |
| PT (1) | PT78260B (enExample) |
| SE (1) | SE455945B (enExample) |
| SU (2) | SU1240355A3 (enExample) |
| YU (1) | YU47384A (enExample) |
| ZA (1) | ZA841938B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6051184A (ja) * | 1983-08-30 | 1985-03-22 | Fujimoto Seiyaku Kk | Ν−シアノイミノチアゾリジン誘導体およびその製造法 |
| US5204360A (en) * | 1985-02-04 | 1993-04-20 | Nihon Bayer Agrochem K.K. | Heterocyclic compounds |
| JPH066585B2 (ja) * | 1985-02-04 | 1994-01-26 | 日本バイエルアグロケム株式会社 | ニトロメチレン誘導体、その製法及び殺虫剤 |
| US5001138B1 (en) * | 1985-02-04 | 1998-01-20 | Bayer Agrochem Kk | Heterocyclic compounds |
| JPH0649699B2 (ja) * | 1985-02-04 | 1994-06-29 | 日本バイエルアグロケム株式会社 | ニトロメチレン誘導体、その製法及び殺虫剤 |
| JPH0730070B2 (ja) * | 1985-10-03 | 1995-04-05 | 日本バイエルアグロケム株式会社 | 新規複素環式化合物 |
| ATE67493T1 (de) * | 1985-02-04 | 1991-10-15 | Bayer Agrochem Kk | Heterocyclische verbindungen. |
| JPH0717621B2 (ja) * | 1986-03-07 | 1995-03-01 | 日本バイエルアグロケム株式会社 | 新規ヘテロ環式化合物 |
| USRE39130E1 (en) | 1986-03-07 | 2006-06-13 | Bayer Cropscience K.K. | Heterocyclic compounds |
| JP2607369B2 (ja) * | 1987-02-20 | 1997-05-07 | 興和株式会社 | 新規な複素環化合物 |
| ATE183085T1 (de) * | 1989-06-21 | 1999-08-15 | Univ Pennsylvania | Behandlung und regulierung der augenentwicklung mit cholinergischen agonisten |
| US5122522A (en) * | 1989-06-21 | 1992-06-16 | The Trustees Of The University Of Pennsylvania | Treatment and control of ocular development |
| HU207047B (en) * | 1989-11-07 | 1993-03-01 | Richter Gedeon Vegyeszet | Process for producing new pyridine derivatives and pharmaceutical copositions comprising same |
| CA2063865A1 (en) * | 1992-03-24 | 1993-09-25 | Karoly Lempert | 2-(substituted imino)-thiazolidines and process for the preparation thereof |
| JP2721805B2 (ja) * | 1994-07-22 | 1998-03-04 | 日本バイエルアグロケム株式会社 | 新規ヘテロ環式化合物 |
| DE4427569A1 (de) * | 1994-08-04 | 1996-02-08 | Bayer Ag | Verfahren zur Herstellung von Cyanimino-1,3-thiazolidin |
| DE4427539A1 (de) * | 1994-08-04 | 1996-02-08 | Sueddeutsche Kalkstickstoff | Verfahren zur Herstellung von 2-Cyaniminothiazolidin |
| DE19904310A1 (de) * | 1999-01-28 | 2000-08-03 | Bayer Ag | Verfahren zur Herstellung heterocyclischer Verbindungen |
| WO2000053582A1 (fr) * | 1999-03-05 | 2000-09-14 | Suntory Limited | COMPOSES HETEROCYCLIQUES POSSEDANT UN EFFET D'ACTIVATION DU RECEPTEUR α4β2 DE L'ACETYLCHOLINE NICOTINIQUE |
| HRP20020667A2 (en) * | 2000-01-19 | 2004-12-31 | Bayer Ag | Method for producing heterocyclic compounds |
| CN1509172A (zh) * | 2001-05-25 | 2004-06-30 | ά����ҩ��˾ | 哌仑西平眼用凝胶剂 |
| KR20050085115A (ko) * | 2002-11-22 | 2005-08-29 | 스미스클라인 비참 코포레이션 | 신규 화합물 |
| JP4847314B2 (ja) * | 2003-04-07 | 2011-12-28 | コーティカル・ピーティーワイ・リミテッド | 炎症性疾患を治療するための新規な方法 |
| WO2010001922A1 (ja) * | 2008-07-01 | 2010-01-07 | 株式会社クレハ | 新規イミノ誘導体とその製造法、並びにこれを含有する殺虫剤 |
| DK2751100T3 (en) * | 2011-09-02 | 2016-01-18 | Bayer Ip Gmbh | METHOD FOR PREPARING [3 - [(6-CHLOR-3-PYRIDINYL) METHYL] -2-THIAZOLIDINYLIDE] CYANAMIDE |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3264316A (en) * | 1963-09-18 | 1966-08-02 | Res Lab Dr C Janssen N V | Certain 2-acylimino-3-substitutedthiazoline-4 compounds |
| DE2205745A1 (de) * | 1972-02-08 | 1973-08-23 | Thomae Gmbh Dr K | Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung |
| US4006156A (en) * | 1975-06-27 | 1977-02-01 | Shell Oil Company | 3-Alkyl-2-(nitromethylene) thiazolidine |
| NL7704322A (nl) * | 1976-05-03 | 1977-11-07 | Merck & Co Inc | Werkwijze voor het bereiden van 2-iminothiazo- lidinen en -thiazolinen. |
| JPS57171986A (en) * | 1981-04-14 | 1982-10-22 | Taiho Yakuhin Kogyo Kk | Heterocylic ring compound containing sulfur |
| JPS5823682A (ja) * | 1981-08-03 | 1983-02-12 | Santen Pharmaceut Co Ltd | 複素五員環化合物 |
| DE3133918A1 (de) * | 1981-08-27 | 1983-03-17 | Bayer Ag, 5090 Leverkusen | 2-arylhydrazino-2-thiazoline, acylderivate derselben, 2-arylazo-2-thiazoline, herstellungsverfahren und ihre verwendung zur bekaempfung von ekto- und endoparasiten |
| JPS58222886A (ja) * | 1982-06-19 | 1983-12-24 | Ricoh Co Ltd | 感熱記録シ−ト |
| JPS5933267A (ja) * | 1982-08-19 | 1984-02-23 | Fujimoto Seiyaku Kk | グアニジン誘導体およびその製造法 |
-
1983
- 1983-03-16 HU HU83888A patent/HU188852B/hu not_active IP Right Cessation
-
1984
- 1984-02-29 DK DK143284A patent/DK143284A/da not_active Application Discontinuation
- 1984-03-12 CH CH1211/84A patent/CH660592A5/de not_active IP Right Cessation
- 1984-03-12 BE BE1/10980A patent/BE899132A/fr not_active IP Right Cessation
- 1984-03-13 PL PL1984252129A patent/PL142909B1/pl unknown
- 1984-03-14 LU LU85248A patent/LU85248A1/fr unknown
- 1984-03-15 FR FR8403985A patent/FR2542740B1/fr not_active Expired
- 1984-03-15 IE IE655/84A patent/IE57101B1/en unknown
- 1984-03-15 NL NL8400817A patent/NL8400817A/nl not_active Application Discontinuation
- 1984-03-15 GB GB08406790A patent/GB2140412B/en not_active Expired
- 1984-03-15 SE SE8401463A patent/SE455945B/sv not_active IP Right Cessation
- 1984-03-15 DD DD84260939A patent/DD216929A5/de not_active IP Right Cessation
- 1984-03-15 NZ NZ207516A patent/NZ207516A/en unknown
- 1984-03-15 PT PT78260A patent/PT78260B/pt not_active IP Right Cessation
- 1984-03-15 JP JP59048270A patent/JPS59196877A/ja active Pending
- 1984-03-15 CA CA000449688A patent/CA1273933A/en not_active Expired - Lifetime
- 1984-03-15 PL PL1984246683A patent/PL142749B1/pl unknown
- 1984-03-15 NO NO841002A patent/NO162858C/no unknown
- 1984-03-15 AT AT0088284A patent/AT383596B/de not_active IP Right Cessation
- 1984-03-15 IN IN186/CAL/84A patent/IN157738B/en unknown
- 1984-03-15 IT IT20057/84A patent/IT1196048B/it active
- 1984-03-15 IL IL71249A patent/IL71249A/xx unknown
- 1984-03-15 CS CS841885A patent/CS241074B2/cs unknown
- 1984-03-15 GR GR74119A patent/GR81883B/el unknown
- 1984-03-15 ZA ZA841938A patent/ZA841938B/xx unknown
- 1984-03-16 DE DE3409801A patent/DE3409801A1/de not_active Withdrawn
- 1984-03-16 AU AU25833/84A patent/AU559753B2/en not_active Ceased
- 1984-03-16 ES ES530738A patent/ES530738A0/es active Granted
- 1984-03-16 YU YU00473/84A patent/YU47384A/xx unknown
- 1984-03-16 FI FI841066A patent/FI79843C/fi not_active IP Right Cessation
- 1984-03-16 US US06/590,486 patent/US4616025A/en not_active Expired - Fee Related
- 1984-03-16 SU SU843713458A patent/SU1240355A3/ru active
- 1984-03-16 KR KR1019840001360A patent/KR840008001A/ko not_active Ceased
- 1984-10-17 SU SU843799805A patent/SU1240356A3/ru active
-
1985
- 1985-06-17 ES ES544286A patent/ES8604179A1/es not_active Expired
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