ES8601210A1 - Procedimiento para la preparacion de nuevos derivados de sinergistinas - Google Patents

Procedimiento para la preparacion de nuevos derivados de sinergistinas

Info

Publication number
ES8601210A1
ES8601210A1 ES537179A ES537179A ES8601210A1 ES 8601210 A1 ES8601210 A1 ES 8601210A1 ES 537179 A ES537179 A ES 537179A ES 537179 A ES537179 A ES 537179A ES 8601210 A1 ES8601210 A1 ES 8601210A1
Authority
ES
Spain
Prior art keywords
formula
preparation
pharmaceutical compositions
radicals
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537179A
Other languages
English (en)
Other versions
ES537179A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES537179A0 publication Critical patent/ES537179A0/es
Publication of ES8601210A1 publication Critical patent/ES8601210A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measurement Of Force In General (AREA)
  • Emergency Protection Circuit Devices (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE SINERGISTINAS DE SUS FORMAS ISOMERAS Y MEZCLAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES DE FORMULA (I) EN LA QUE Y ES HIDROGENO O DIMETILAMINO; R1 Y R2 FORMAN EN CONJUNTO UN ENLACE; Y R PUEDE SER UNO O VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA R-H CON UN COMPUESTO DE FORMULA (II) EN LA QUE Y ES EL MISMO QUE EN LA FORMULA (I) Y R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REACCION SE EFECTUA EN UN DISOLVENTE ORGANICO INERTE EN PRESENCIA DE UN ACIDO A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 50JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIBACTERIANA.
ES537179A 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas Expired ES8601210A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8311705A FR2549063B1 (fr) 1983-07-13 1983-07-13 Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
ES537179A0 ES537179A0 (es) 1985-10-16
ES8601210A1 true ES8601210A1 (es) 1985-10-16

Family

ID=9290812

Family Applications (3)

Application Number Title Priority Date Filing Date
ES534313A Expired ES8504201A1 (es) 1983-07-13 1984-07-13 Procedimiento para la preparacion de nuevos derivados de sinergistinas
ES537179A Expired ES8601210A1 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas
ES537180A Granted ES537180A0 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES534313A Expired ES8504201A1 (es) 1983-07-13 1984-07-13 Procedimiento para la preparacion de nuevos derivados de sinergistinas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES537180A Granted ES537180A0 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas

Country Status (17)

Country Link
US (1) US4618599A (es)
EP (1) EP0133097B1 (es)
JP (1) JPS6038386A (es)
KR (1) KR910005848B1 (es)
AT (1) ATE25691T1 (es)
AU (1) AU567570B2 (es)
CA (1) CA1213583A (es)
DE (1) DE3462507D1 (es)
DK (1) DK169258B1 (es)
ES (3) ES8504201A1 (es)
FI (2) FI78105C (es)
FR (1) FR2549063B1 (es)
GR (1) GR81555B (es)
IL (1) IL72397A (es)
PT (1) PT78894B (es)
SU (3) SU1421260A3 (es)
ZA (1) ZA845316B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549065B1 (fr) * 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr) * 1986-05-22 1988-09-09 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2655343B1 (fr) * 1989-12-05 1992-05-07 Rhone Poulenc Sante Procede de preparation de synergistine.
FR2664894A1 (fr) * 1990-07-19 1992-01-24 Rhone Poulenc Sante Nouveaux derives de streptogramines et leur preparation.
IL121821A (en) * 1993-02-17 2000-02-17 Rhone Poulenc Rorer Sa Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2723373B1 (fr) 1994-08-02 1996-09-13 Rhone Poulenc Rorer Sa Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
FR2796949B1 (fr) * 1999-07-27 2001-09-21 Aventis Pharma Sa Derives de streptogramines, leur preparation et les compositions qui les contiennent
CN101273042B (zh) * 2005-07-29 2013-11-06 泰博特克药品有限公司 丙型肝炎病毒的大环抑制剂
JP2008057849A (ja) * 2006-08-31 2008-03-13 Denso Corp 熱交換器の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4355112A (en) * 1977-06-06 1982-10-19 Sanraku-Ocean Co., Ltd. Streptomyces culture

Also Published As

Publication number Publication date
FI80456B (fi) 1990-02-28
IL72397A0 (en) 1984-11-30
SU1445560A3 (ru) 1988-12-15
AU567570B2 (en) 1987-11-26
ES534313A0 (es) 1985-04-01
KR850001212A (ko) 1985-03-16
FR2549063A1 (fr) 1985-01-18
SU1421260A3 (ru) 1988-08-30
EP0133097A1 (fr) 1985-02-13
ES537179A0 (es) 1985-10-16
ZA845316B (en) 1985-02-27
SU1456019A3 (ru) 1989-01-30
PT78894A (fr) 1984-08-01
DE3462507D1 (en) 1987-04-09
ES8601211A1 (es) 1985-10-16
FI78105B (fi) 1989-02-28
JPH0522718B2 (es) 1993-03-30
JPS6038386A (ja) 1985-02-27
FI842812A7 (fi) 1985-01-14
FI874654A0 (fi) 1987-10-22
FI78105C (fi) 1989-06-12
DK342584A (da) 1985-01-14
US4618599A (en) 1986-10-21
IL72397A (en) 1987-10-30
ES537180A0 (es) 1985-10-16
CA1213583A (fr) 1986-11-04
FI80456C (fi) 1990-06-11
KR910005848B1 (ko) 1991-08-05
EP0133097B1 (fr) 1987-03-04
FI874654A7 (fi) 1987-10-22
FR2549063B1 (fr) 1985-10-25
DK169258B1 (da) 1994-09-26
FI842812A0 (fi) 1984-07-12
ES8504201A1 (es) 1985-04-01
ATE25691T1 (de) 1987-03-15
DK342584D0 (da) 1984-07-12
AU3047284A (en) 1985-01-17
PT78894B (fr) 1986-08-08
GR81555B (es) 1984-12-11

Similar Documents

Publication Publication Date Title
ES8303383A1 (es) Un procedimiento para la preparacion de derivados del 1,2,5-tiadiazol
ES8401970A1 (es) Un procedimiento para la preparacion de derivados de benzoisotiazol y benzoisoxazol piperazina.
ES8304095A1 (es) Un procedimiento para la preparacion de derivados de quinazolina.
AR241247A1 (es) Procedimiento para la preparacion de nuevos derivados de imidazo ¡4,5-c¿ piridina.
ES8303293A1 (es) "procedimiento de preparar derivados carboxamidicos".
ES8204428A1 (es) Procedimiento para preparar alfa-aril-1h-1,2,4-triazol-1- etanoles
ES8801642A1 (es) Un procedimiento para la preparacion de l,2,4-triazoles
ES8303426A1 (es) Un procedimiento para la preparacion de un compuesto de cefalosporina.
ES8301980A1 (es) Procedimiento para la preparacion de 8-arilalcohil-3-fenil-3-nortropanoles .
ES8603497A1 (es) Procedimiento para preparar derivados de cefalosporina
ES8606879A1 (es) Un procedimiento para la preparacion de derivados esteroida-les
ES8306750A1 (es) Un procedimiento para la preparacion de 2-guanidino-4-heteroariltiazoles.
ES8307824A1 (es) Un procedimiento para preparar nuevos compuestos de cefem.
ES8706654A1 (es) Un procedimiento para la preparacion de nuevos derivados de benzotiazina
ES8705453A1 (es) Un procedimiento para la preparacion de derivados de cefalosporina.
ES8601210A1 (es) Procedimiento para la preparacion de nuevos derivados de sinergistinas
ES8304070A1 (es) "procedimiento para la preparacion de nuevas amidas de acidos carboxilicos".
ES8701145A1 (es) Un procedimiento para la preparacion de derivados de tetrahidronaftaleno.
ES8301883A1 (es) Procedimiento para la preparacion de derivados de ciclohexe-no
ES8609323A1 (es) Un procedimiento para la preparacion de hexahidro-arilquinolizinas sustituidas.
ES8204416A1 (es) Un procedimiento para la produccion de un derivado de benza-mida
ES8800193A1 (es) Procedimiento para preparar 2,4-difenil-1,3-dioxanos
ES8305707A1 (es) Procedimiento para preparar derivados de quanadina.
ES8801834A1 (es) Procedimiento para preparar 1,2-dihidronaftalenos y derivados 1-oxa, 1-tia 1-sulfinilo y 1-sulfonilo de los mismos
ES8303424A1 (es) Procedimiento para la obtencion de esteres del acido 7b-(2-(2-animo-4-tiazolil)-2-(sin)-metoxiimino-acetamido)-3-cefem-4-caboxilico.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612