ES8801834A1 - Procedimiento para preparar 1,2-dihidronaftalenos y derivados 1-oxa, 1-tia 1-sulfinilo y 1-sulfonilo de los mismos - Google Patents

Procedimiento para preparar 1,2-dihidronaftalenos y derivados 1-oxa, 1-tia 1-sulfinilo y 1-sulfonilo de los mismos

Info

Publication number
ES8801834A1
ES8801834A1 ES557389A ES557389A ES8801834A1 ES 8801834 A1 ES8801834 A1 ES 8801834A1 ES 557389 A ES557389 A ES 557389A ES 557389 A ES557389 A ES 557389A ES 8801834 A1 ES8801834 A1 ES 8801834A1
Authority
ES
Spain
Prior art keywords
free
etherified
sulfur
alkylene
functionally modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557389A
Other languages
English (en)
Other versions
ES557389A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Consumer Healthcare SARL
Original Assignee
Zyma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zyma SA filed Critical Zyma SA
Publication of ES557389A0 publication Critical patent/ES557389A0/es
Publication of ES8801834A1 publication Critical patent/ES8801834A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 1,2-DIHIDRONAFTALENOS, DE FORMULA (I), DE SUS TAUTOMEROS, ESTEROISOMEROS, ISOMEROS OPTICOS Y SALES FISIOLOGICAMENTE COMPATIBLES. COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA HS-CH2-Z, O UNA DE SUS SALES MERCAPTIDAS DE METAL ALCALINO, A UNA TEMPERATURA COMPRENDIDA ENTRE C20JC Y 200JC, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE UNO DE X1 Y X2 ES GRUPO SALIENTE Y EL OTRO ES FORMILO Y X, Y, Z, R1 Y R2 PUEDEN SER VARIOS TIPOSDE RADICALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES DEL TRACTO RESPIRATORIO.
ES557389A 1985-02-23 1987-02-13 Procedimiento para preparar 1,2-dihidronaftalenos y derivados 1-oxa, 1-tia 1-sulfinilo y 1-sulfonilo de los mismos Expired ES8801834A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858504702A GB8504702D0 (en) 1985-02-23 1985-02-23 Tricyclic compounds

Publications (2)

Publication Number Publication Date
ES557389A0 ES557389A0 (es) 1988-02-16
ES8801834A1 true ES8801834A1 (es) 1988-02-16

Family

ID=10574972

Family Applications (2)

Application Number Title Priority Date Filing Date
ES552284A Expired ES8708223A1 (es) 1985-02-23 1986-02-21 Procedimiento para preparar 1,2-dihidro-naftalenos y derivados 1-oxa,1-tia, 1-sulfinilo y 1-sulfonilo de los mismos
ES557389A Expired ES8801834A1 (es) 1985-02-23 1987-02-13 Procedimiento para preparar 1,2-dihidronaftalenos y derivados 1-oxa, 1-tia 1-sulfinilo y 1-sulfonilo de los mismos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES552284A Expired ES8708223A1 (es) 1985-02-23 1986-02-21 Procedimiento para preparar 1,2-dihidro-naftalenos y derivados 1-oxa,1-tia, 1-sulfinilo y 1-sulfonilo de los mismos

Country Status (19)

Country Link
US (1) US4797414A (es)
EP (1) EP0193493A3 (es)
JP (1) JPS61194081A (es)
KR (1) KR860006470A (es)
AU (1) AU593238B2 (es)
CA (1) CA1284326C (es)
DD (1) DD249019A5 (es)
DK (1) DK81586A (es)
ES (2) ES8708223A1 (es)
FI (1) FI860738A (es)
GB (1) GB8504702D0 (es)
GR (1) GR860500B (es)
HU (1) HU196075B (es)
IL (1) IL77919A0 (es)
NO (1) NO164172C (es)
NZ (1) NZ215253A (es)
PH (1) PH24908A (es)
PT (1) PT82061B (es)
ZA (1) ZA861304B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003256650A1 (en) * 2002-07-19 2004-02-09 Pharmacia Corporation Substituted thiophene carboxamide compounds for the treatment of inflammation
JP2006151810A (ja) * 2002-12-26 2006-06-15 Daiichi Asubio Pharma Co Ltd ジヒドロチエノキノリン誘導体及びそれを含む細胞接着阻害剤
JPWO2005012284A1 (ja) * 2003-07-31 2007-09-27 大正製薬株式会社 ４，５−ジヒドロナフト［１，２−ｂ］チオフェン誘導体
WO2006080406A1 (ja) * 2005-01-28 2006-08-03 Taisho Pharmaceutical Co., Ltd. 三環性化合物
WO2006080439A1 (ja) * 2005-01-28 2006-08-03 Taisho Pharmaceutical Co., Ltd. 三環性化合物
MX2010010659A (es) * 2008-03-31 2010-10-26 Genentech Inc Compuestos de benzopirano y benzoxepina, inhibidores de fosfoinoinositida 3-cinasas y metodos para utilizarlos.
AU2010299820A1 (en) 2009-09-28 2012-04-19 F. Hoffmann-La Roche Ag Benzoxepin PI3K inhibitor compounds and methods of use
EP2483278B1 (en) 2009-09-28 2013-12-25 F. Hoffmann-La Roche AG Benzoxazepin pi3k inhibitor compounds and their use in the treatment of cancer
BR112013024122A2 (pt) 2011-03-21 2019-09-24 Hoffmann La Roche compostos de benzoxazepina seletivos para p110 delta pi3k e métodos de uso
PL2714675T3 (pl) * 2011-05-27 2019-07-31 Lexicon Pharmaceuticals, Inc. Inhibitory acetyloesterazy pektynowej Notum na bazie 4H-tieno[3,2-c]chromenu i sposoby ich zastosowania

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1917601C3 (de) * 1969-04-05 1980-09-25 Bayer Ag, 5090 Leverkusen Benzoxazolyl-(2)-dihydronaphtho [4,5-b] thiophene und deren Verwendung als optische Aufheller
US3656906A (en) * 1970-04-13 1972-04-18 Little Inc A Method for detecting and quantitating the presence of cannabinoids and analogs thereof in biological materials and resulting products
SE7801074L (sv) * 1977-02-08 1978-08-09 Sandoz Ag Organiska foreningar, deras framstellning och anvendning
US4268516A (en) * 1978-10-11 1981-05-19 Pfizer Inc. [1]Benzothiopyrano[4,3-c]pyrazoles as immunoregulatory agents
DE3023301A1 (de) * 1980-06-21 1982-01-14 Bayer Ag, 5090 Leverkusen Benzoxazolyldihydronaphthothiophenverbindungen sowie verwendung als optische aufheller

Also Published As

Publication number Publication date
ES552284A0 (es) 1987-10-01
DD249019A5 (de) 1987-08-26
ES557389A0 (es) 1988-02-16
AU593238B2 (en) 1990-02-08
HUT41762A (en) 1987-05-28
FI860738A (fi) 1986-08-24
NO164172C (no) 1990-09-05
US4797414A (en) 1989-01-10
EP0193493A2 (en) 1986-09-03
NO860654L (no) 1986-08-25
NO164172B (no) 1990-05-28
GB8504702D0 (en) 1985-03-27
PH24908A (en) 1990-12-26
IL77919A0 (en) 1986-09-30
NZ215253A (en) 1989-10-27
ES8708223A1 (es) 1987-10-01
AU5387586A (en) 1986-08-28
PT82061A (en) 1986-03-01
KR860006470A (ko) 1986-09-11
DK81586D0 (da) 1986-02-21
GR860500B (en) 1986-06-18
CA1284326C (en) 1991-05-21
PT82061B (pt) 1988-07-01
HU196075B (en) 1988-09-28
DK81586A (da) 1986-08-24
JPS61194081A (ja) 1986-08-28
ZA861304B (en) 1986-10-29
EP0193493A3 (en) 1988-01-13
FI860738A0 (fi) 1986-02-19

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