ES8704181A1 - Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i - Google Patents

Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i

Info

Publication number
ES8704181A1
ES8704181A1 ES550987A ES550987A ES8704181A1 ES 8704181 A1 ES8704181 A1 ES 8704181A1 ES 550987 A ES550987 A ES 550987A ES 550987 A ES550987 A ES 550987A ES 8704181 A1 ES8704181 A1 ES 8704181A1
Authority
ES
Spain
Prior art keywords
bis
gold
selenosugar
thiosugar
diphenylphosphino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550987A
Other languages
English (en)
Other versions
ES550987A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/781,438 external-priority patent/US4645756A/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES550987A0 publication Critical patent/ES550987A0/es
Publication of ES8704181A1 publication Critical patent/ES8704181A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DE BIS(DIFENILFOSFINO)ALQUILBIS-ORO(I), DE FORMULA (I). COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN TIOAZUCAR SODICO O SELENOTIOAZUCAR SODICO ADECUADO PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LA QUE A ES (CH2)N O CIS CHFCH, N VALE 1 A 6 Y W ES TIOAZUCAR O SELENOAZUCAR. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, BAJO ATMOSFERA DE ARGON, A LA TEMPERATURA AMBIENTE. TAMBIEN SE PUEDE PREPARAR EL COMPUESTO DE FORMULA (I), EN LA QUE W ES TIOAZUCAR ACETILADO O SELENOAZUCAR ACETILADO Y, A CONTINUACION HIDROLIZAR CON UNA BASE EL PRODUCTO FORMADO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE CELULAS TUMORALES.
ES550987A 1985-01-22 1986-01-17 Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i Expired ES8704181A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69341685A 1985-01-22 1985-01-22
US06/781,438 US4645756A (en) 1985-09-27 1985-09-27 [α,ω-bis(diphenylphosphino)hydrocarbon]bis[(thiosugar)gold] and bis[(selenosugar)gold] derivatives, pharmaceutical compositions and method of use

Publications (2)

Publication Number Publication Date
ES550987A0 ES550987A0 (es) 1987-03-16
ES8704181A1 true ES8704181A1 (es) 1987-03-16

Family

ID=27105166

Family Applications (1)

Application Number Title Priority Date Filing Date
ES550987A Expired ES8704181A1 (es) 1985-01-22 1986-01-17 Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i

Country Status (6)

Country Link
EP (1) EP0189306A3 (es)
AU (1) AU581954B2 (es)
DK (1) DK33886A (es)
ES (1) ES8704181A1 (es)
GR (1) GR860161B (es)
PT (1) PT81874B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0329416D0 (en) * 2003-12-19 2004-01-21 Univ Salford The Treatment of cancer
IT202100012806A1 (it) 2021-05-18 2021-08-18 Avicenna Natural Inst Glicoconiugato sintetico e membrana polimerica comprendente tale glicoconiugato

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096250A (en) * 1977-02-25 1978-06-20 Smithkline Corporation Tri-substituted phosphinegold(I) 1-thio-β-D-glucopyranosides
JPS58148823A (ja) * 1982-02-11 1983-09-05 リチヤ−ド・エフ・ストツケル 金毒解毒剤
DK166686A (da) * 1985-04-16 1986-10-17 Smithkline Beckman Corp Phosphinforbindelser, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse forbindelser
EP0202854A3 (en) * 1985-05-20 1988-01-13 Smithkline Beecham Corporation Phosphine gold compounds

Also Published As

Publication number Publication date
ES550987A0 (es) 1987-03-16
PT81874A (en) 1986-02-01
AU5248786A (en) 1986-07-31
DK33886D0 (da) 1986-01-22
PT81874B (en) 1988-01-12
EP0189306A2 (en) 1986-07-30
DK33886A (da) 1986-07-23
EP0189306A3 (en) 1989-02-22
GR860161B (en) 1986-05-22
AU581954B2 (en) 1989-03-09

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