ES8706125A1 - Un procedimiento para preparar nuevos derivados de imidiazol. - Google Patents

Un procedimiento para preparar nuevos derivados de imidiazol.

Info

Publication number
ES8706125A1
ES8706125A1 ES550972A ES550972A ES8706125A1 ES 8706125 A1 ES8706125 A1 ES 8706125A1 ES 550972 A ES550972 A ES 550972A ES 550972 A ES550972 A ES 550972A ES 8706125 A1 ES8706125 A1 ES 8706125A1
Authority
ES
Spain
Prior art keywords
preparation
therapeutic use
imidazole derivatives
thromboxane
prophylaxis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550972A
Other languages
English (en)
Other versions
ES550972A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES8706125A1 publication Critical patent/ES8706125A1/es
Publication of ES550972A0 publication Critical patent/ES550972A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

METODO DE PREPARAR NUEVOS PREPARADOS DE IMIDAZOL. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) A TEMPERATURA ENTRE C10 Y 100JC DURANTE 20 MINUTOS Y 100 HORAS, PARA PRODUCIR UN COMPUESTO DE FORMULA (IV), Y OXIDAR EL COMPUESTO OBTENIDO CON UN AGENTE OXIDANTE, EN UN DISOLVENTE, A TEMPERATURA ENTRE 0JC Y LA AMBIENTE, PARA OBTENER DERIVADOS DE IMIDAZOL DE FORMULA (I) DONDE R1 ES H O UN GRUPO METILO; R2 ES H O UN GRUPO ALQUILO DE C 1 A 6, UN GRUPO ALQUENILO DE C 2 A 6 Y OTROS; R4 ES H O UN GRUPO ALQUILO DE C 1 A 6, GRUPOS ALQUINILO DE C 2 A 6 Y OTROS; R3 ES UN GRUPO CARBOXI; X, Y, Z SON H Y OTROS; Y N ES 0, 1 O 2. TIENEN APLICACIONES PARA TRATAR ESTADOS TROMBOTICOS.
ES550972A 1985-01-16 1986-01-16 Un procedimiento para preparar nuevos derivados de imidiazol. Expired ES8706125A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP405585 1985-01-16

Publications (2)

Publication Number Publication Date
ES8706125A1 true ES8706125A1 (es) 1987-06-01
ES550972A0 ES550972A0 (es) 1987-06-01

Family

ID=11574190

Family Applications (2)

Application Number Title Priority Date Filing Date
ES550972A Expired ES8706125A1 (es) 1985-01-16 1986-01-16 Un procedimiento para preparar nuevos derivados de imidiazol.
ES557436A Expired ES8801636A1 (es) 1985-01-16 1987-03-05 Un procedimiento para preparar nuevos derivados de imidazol

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557436A Expired ES8801636A1 (es) 1985-01-16 1987-03-05 Un procedimiento para preparar nuevos derivados de imidazol

Country Status (13)

Country Link
US (1) US4894385A (es)
EP (1) EP0188383B1 (es)
JP (1) JPH0625141B2 (es)
KR (1) KR930004674B1 (es)
AT (1) ATE104967T1 (es)
AU (1) AU582206B2 (es)
CA (1) CA1296009C (es)
DE (1) DE3689807T2 (es)
DK (1) DK20886A (es)
ES (2) ES8706125A1 (es)
FI (1) FI90866C (es)
NO (1) NO166445C (es)
ZA (1) ZA86286B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960010343B1 (ko) * 1987-12-09 1996-07-30 에스에스 세이야꾸 가부시끼가이샤 이미다졸 유도체
US5308860A (en) * 1993-01-15 1994-05-03 Rohm And Haas Company Cyanosulfonylethyltriazoles
JP2002167378A (ja) * 2000-09-22 2002-06-11 Ss Pharmaceut Co Ltd イミダゾール誘導体又はその塩
JP2006347882A (ja) * 2003-09-02 2006-12-28 Ss Pharmaceut Co Ltd ベンジルアルコール誘導体又はその塩

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860862D1 (en) * 1977-10-13 1981-10-29 Siegfried Ag Imidazolylethylene-oxyalkyloxy derivatives and their thio analogues, methods for their preparation and pharmaceutical compositions containing them
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
DK471479A (da) * 1978-12-13 1980-06-14 Pfizer Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
JPS56120670A (en) * 1980-02-27 1981-09-22 Teijin Ltd 1-substituted imidazole derivative and its preparation
GB8400254D0 (en) * 1984-01-06 1984-02-08 Searle & Co Substituted alklidene imidazoles

Also Published As

Publication number Publication date
CA1296009C (en) 1992-02-18
ES557436A0 (es) 1988-02-16
ATE104967T1 (de) 1994-05-15
DK20886D0 (da) 1986-01-16
JPH0625141B2 (ja) 1994-04-06
AU5242586A (en) 1986-07-24
NO166445B (no) 1991-04-15
FI860210A (fi) 1986-07-17
NO860114L (no) 1986-07-17
FI90866C (fi) 1994-04-11
ES8801636A1 (es) 1988-02-16
DE3689807T2 (de) 1994-08-25
ZA86286B (en) 1986-09-24
ES550972A0 (es) 1987-06-01
US4894385A (en) 1990-01-16
KR860005793A (ko) 1986-08-13
AU582206B2 (en) 1989-03-16
FI90866B (fi) 1993-12-31
EP0188383B1 (en) 1994-04-27
NO166445C (no) 1991-08-07
KR930004674B1 (ko) 1993-06-03
EP0188383A3 (en) 1988-06-22
DE3689807D1 (de) 1994-06-01
EP0188383A2 (en) 1986-07-23
FI860210A0 (fi) 1986-01-16
JPS61267557A (ja) 1986-11-27
DK20886A (da) 1986-07-17

Similar Documents

Publication Publication Date Title
ES473451A1 (es) Un procedimiento para la preparacion de derivados de imida- zol.
ES8707947A1 (es) Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos.
EP0178189A3 (en) Pyridazinone derivatives, their preparation and use
ES8304969A1 (es) Procedimiento para la obtencion de 2-aril-3,4-diazabiciclo 4.n.0-alq-2-en-5-onas.
ES8706713A1 (es) Un procedimiento para preparar derivados de 4'-desmetil-4-epipodofilotoxina
ES8505518A1 (es) Procedimiento para preparar derivados de aminoacidos
DE3477488D1 (en) Polymethoxybenzyl piperazine derivatives, processes for their preparation and pharmaceutical compositions containing said derivatives
ES8706125A1 (es) Un procedimiento para preparar nuevos derivados de imidiazol.
DK45987A (da) Thianaphthenderivater, deres fremstilling og anvendelse
HUT41025A (en) Process for preparing octahydro-indolizine derivatives and pharmaceutical compositions containing such compounds as active ingredients
NZ219052A (en) Octahydroindolizine derivatives and pharmaceutical compositions
DE3374005D1 (en) 1-methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle
ES2012559A6 (es) Nuevos isopolipeptidos y procedimiento para su preparacion.
ES8305758A1 (es) "un procedimiento para la preparacion de 2-(1,4-benzodioxan-2-il-metil)-imidazolina".
ES8706111A1 (es) Procedimiento de obtencion de derivados amidicos a partir de aminas que contienen azufre y acidos alifaticos insaturados c5-c18
NZ213780A (en) Diphenylmethylimine derivatives and pharmaceutical compositions
ES8608315A1 (es) Procedimiento para la obtencion de un somnifero conteniendo lorazepam
ES486799A1 (es) Un procedimiento de preparacion de 10-bromo-vincamina
ES8306758A1 (es) Un procedimiento para la preparacion de un derivado de beta-lactama.
ES2056721A1 (es) Mejoras en el objeto de la patente de invencion n{ 9101355 que se refiere a procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas.
ES8704181A1 (es) Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i
ES8307782A1 (es) Procedimiento para la preparacion de un nuevo derivado perteneciente a la familia de los 3-amino-1-heteroariloxi-2-propanoles.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612