ES8307782A1 - Procedimiento para la preparacion de un nuevo derivado perteneciente a la familia de los 3-amino-1-heteroariloxi-2-propanoles. - Google Patents
Procedimiento para la preparacion de un nuevo derivado perteneciente a la familia de los 3-amino-1-heteroariloxi-2-propanoles.Info
- Publication number
- ES8307782A1 ES8307782A1 ES516988A ES516988A ES8307782A1 ES 8307782 A1 ES8307782 A1 ES 8307782A1 ES 516988 A ES516988 A ES 516988A ES 516988 A ES516988 A ES 516988A ES 8307782 A1 ES8307782 A1 ES 8307782A1
- Authority
- ES
- Spain
- Prior art keywords
- amino
- heteroaryloxy
- therapy
- derivatives
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Furan Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS PERTENECIENTES A LA FAMILIA DE LOS 3-AMINO-1-HETEROARILOXI-2-PROPANOLES, DE FORMULA GENERAL (I), EN LA QUE R REPRESENTA UN GRUPO ISOPROPILO O TERTIOBUTILO, Y SUS SALES DE ADICION DE ACIDO. CONSISTE EN HACER REACCIONAR EL 2,4-DIACETIL-5-HIDROXIBENZOFURANO, DE FORMULA ESTRUCTURAL (II), CON UN EPOXIDO HALOGENADO DE FORMULA (III), EN LA QUE HA L REPRESENTA CL O BR, PARA OBTENER EL 2,4-DIACETIL-5-(2,3-EPOXI-PROPILOXI)-BENZOFURANO. EL COMPUESTO OBTENIDO EN LA REACCION ANTERIOR SE HACE REACCIONAR CON UNA AMINA: NH < 2R, EN DONDE R TIENE EL SIGNIFICADO YA INDICADO. DE APLICACION EN TRATAMIENTOS TERAPEUTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8120471A FR2515649A1 (fr) | 1981-10-30 | 1981-10-30 | Nouveaux derives appartenant a la famille des 3-amino-1-heteroaryloxy-2-propanols, utilisation en therapeutique et procede de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES516988A0 ES516988A0 (es) | 1983-08-01 |
| ES8307782A1 true ES8307782A1 (es) | 1983-08-01 |
Family
ID=9263594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES516988A Expired ES8307782A1 (es) | 1981-10-30 | 1982-10-29 | Procedimiento para la preparacion de un nuevo derivado perteneciente a la familia de los 3-amino-1-heteroariloxi-2-propanoles. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4485111A (es) |
| EP (1) | EP0078735B1 (es) |
| JP (1) | JPS58121287A (es) |
| AT (1) | ATE15669T1 (es) |
| AU (1) | AU550498B2 (es) |
| CA (1) | CA1197516A (es) |
| DE (1) | DE3266420D1 (es) |
| DK (1) | DK481082A (es) |
| ES (1) | ES8307782A1 (es) |
| FI (1) | FI72515C (es) |
| FR (1) | FR2515649A1 (es) |
| GR (1) | GR76240B (es) |
| IE (1) | IE54054B1 (es) |
| NO (1) | NO157419C (es) |
| NZ (1) | NZ202326A (es) |
| ZA (1) | ZA827930B (es) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL300664A (es) * | 1962-11-23 | |||
| FR1503510A (fr) * | 1962-11-23 | 1967-12-01 | Ici Ltd | Composés naphtaléniques et leur procédé de fabrication |
| US3853923A (en) * | 1971-05-13 | 1974-12-10 | Kakenyaku Kako Kk | 2-substituted-(2-hydroxy-3-lower alkaminopropoxy)-benzofurans |
-
1981
- 1981-10-30 FR FR8120471A patent/FR2515649A1/fr active Granted
-
1982
- 1982-10-22 IE IE2552/82A patent/IE54054B1/en unknown
- 1982-10-25 EP EP82401959A patent/EP0078735B1/fr not_active Expired
- 1982-10-25 AT AT82401959T patent/ATE15669T1/de not_active IP Right Cessation
- 1982-10-25 DE DE8282401959T patent/DE3266420D1/de not_active Expired
- 1982-10-26 GR GR69643A patent/GR76240B/el unknown
- 1982-10-27 CA CA000414274A patent/CA1197516A/en not_active Expired
- 1982-10-28 US US06/437,210 patent/US4485111A/en not_active Expired - Fee Related
- 1982-10-29 FI FI823707A patent/FI72515C/fi not_active IP Right Cessation
- 1982-10-29 ZA ZA827930A patent/ZA827930B/xx unknown
- 1982-10-29 NZ NZ202326A patent/NZ202326A/en unknown
- 1982-10-29 DK DK481082A patent/DK481082A/da not_active Application Discontinuation
- 1982-10-29 AU AU90082/82A patent/AU550498B2/en not_active Ceased
- 1982-10-29 NO NO823611A patent/NO157419C/no unknown
- 1982-10-29 ES ES516988A patent/ES8307782A1/es not_active Expired
- 1982-10-30 JP JP57191729A patent/JPS58121287A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4485111A (en) | 1984-11-27 |
| FR2515649A1 (fr) | 1983-05-06 |
| AU9008282A (en) | 1983-05-05 |
| DE3266420D1 (en) | 1985-10-24 |
| NO823611L (no) | 1983-05-02 |
| EP0078735A1 (fr) | 1983-05-11 |
| NO157419B (no) | 1987-12-07 |
| GR76240B (es) | 1984-08-04 |
| IE822552L (en) | 1983-04-30 |
| FI72515B (fi) | 1987-02-27 |
| FI823707L (fi) | 1983-05-01 |
| DK481082A (da) | 1983-05-01 |
| FI823707A0 (fi) | 1982-10-29 |
| EP0078735B1 (fr) | 1985-09-18 |
| JPS58121287A (ja) | 1983-07-19 |
| FR2515649B1 (es) | 1984-06-29 |
| ES516988A0 (es) | 1983-08-01 |
| CA1197516A (en) | 1985-12-03 |
| ZA827930B (en) | 1983-08-31 |
| NO157419C (no) | 1988-03-16 |
| IE54054B1 (en) | 1989-05-24 |
| FI72515C (fi) | 1987-06-08 |
| NZ202326A (en) | 1985-08-30 |
| AU550498B2 (en) | 1986-03-20 |
| ATE15669T1 (de) | 1985-10-15 |
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