ES8608315A1 - Procedimiento para la obtencion de un somnifero conteniendo lorazepam - Google Patents

Procedimiento para la obtencion de un somnifero conteniendo lorazepam

Info

Publication number
ES8608315A1
ES8608315A1 ES538171A ES538171A ES8608315A1 ES 8608315 A1 ES8608315 A1 ES 8608315A1 ES 538171 A ES538171 A ES 538171A ES 538171 A ES538171 A ES 538171A ES 8608315 A1 ES8608315 A1 ES 8608315A1
Authority
ES
Spain
Prior art keywords
lorazepam
soporific
diphenhydramine
weight ratio
containing lorazepam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538171A
Other languages
English (en)
Other versions
ES538171A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medichemie AG
Original Assignee
Medichemie AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichemie AG filed Critical Medichemie AG
Publication of ES538171A0 publication Critical patent/ES538171A0/es
Publication of ES8608315A1 publication Critical patent/ES8608315A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER UN SOMNIFERO QUE CONTIENE LORAZEPAM. COMPRENDE: A) AMASAR A (A) CON FECULA DE MAIZ, DE PATATA, LACTONA, POLVO DE CELULOSA, ESTEARATO DE MAGNESIO Y TALCO; B) GRANULAR A LA MASA DE A) A TRAVES DE UN TAMIZ; C) PRENSAR A LOS GRANULADOS CON (B) EN UNA PROPORCION DE 1:10 Y 1:25, PARA FORMAR TABLETAS; Y D) REVESTIR A LAS TABLETAS CON AZUCAR Y/O PELICULA POLIMERA. SIENDO: (A), 7-CLORO-5-(2-CLOROFENIL)-1,3-DIHIDRO-3-HIDROXI-2H-1,4-BENZODIAZEPIN-2-ONA-(LORAZEPAM); (B), HIDROCLORURO DE (C); Y (C), 2-(DIFENIL-METOXI)-N,N-DIMETIL-ETANAMINA. SE ADMINISTRA POR VIA ORAL O ENTERAL.
ES538171A 1984-02-08 1984-11-30 Procedimiento para la obtencion de un somnifero conteniendo lorazepam Expired ES8608315A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3404316A DE3404316C1 (de) 1984-02-08 1984-02-08 Lorazepam-haltiges Schlafmittel

Publications (2)

Publication Number Publication Date
ES538171A0 ES538171A0 (es) 1986-06-16
ES8608315A1 true ES8608315A1 (es) 1986-06-16

Family

ID=6227049

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538171A Expired ES8608315A1 (es) 1984-02-08 1984-11-30 Procedimiento para la obtencion de un somnifero conteniendo lorazepam

Country Status (14)

Country Link
US (1) US4590191A (es)
EP (1) EP0151245B1 (es)
JP (1) JPS60174718A (es)
KR (1) KR880002523B1 (es)
AT (1) ATE56871T1 (es)
AU (1) AU562271B2 (es)
CA (1) CA1237078A (es)
DE (2) DE3404316C1 (es)
DK (1) DK551384A (es)
ES (1) ES8608315A1 (es)
GR (1) GR81060B (es)
IE (1) IE57933B1 (es)
PT (1) PT79647B (es)
ZA (1) ZA849270B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0930884B1 (de) * 1996-10-11 2002-12-18 Medichemie Ag Chronische verwendung von lorazepam und diphenhydramin
ITRM20020357A1 (it) * 2002-07-03 2004-01-05 Foscama Biomed Chim Farma Composizione liquida per la somministrazione orale di lorazepam.
US20080031944A1 (en) * 2006-08-04 2008-02-07 Cima Labs Inc. Stabilization of lorazepam

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2155832B1 (es) * 1971-10-08 1975-08-01 Delalande Sa

Also Published As

Publication number Publication date
JPH0445493B2 (es) 1992-07-27
IE843026L (en) 1985-08-08
PT79647A (en) 1985-01-01
AU3609384A (en) 1985-08-15
KR850005776A (ko) 1985-09-26
EP0151245A3 (en) 1988-03-30
GR81060B (en) 1985-05-20
KR880002523B1 (ko) 1988-11-28
DK551384A (da) 1985-08-09
EP0151245B1 (de) 1990-09-26
IE57933B1 (en) 1993-05-19
ZA849270B (en) 1985-07-31
DE3483318D1 (de) 1990-10-31
EP0151245A2 (de) 1985-08-14
JPS60174718A (ja) 1985-09-09
AU562271B2 (en) 1987-06-04
PT79647B (en) 1986-10-21
DE3404316C1 (de) 1985-06-20
ES538171A0 (es) 1986-06-16
CA1237078A (en) 1988-05-24
US4590191A (en) 1986-05-20
ATE56871T1 (de) 1990-10-15
DK551384D0 (da) 1984-11-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020506