KR850005776A - 로라제팜 함유 수면제 제조방법 - Google Patents

로라제팜 함유 수면제 제조방법 Download PDF

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Publication number
KR850005776A
KR850005776A KR1019840007749A KR840007749A KR850005776A KR 850005776 A KR850005776 A KR 850005776A KR 1019840007749 A KR1019840007749 A KR 1019840007749A KR 840007749 A KR840007749 A KR 840007749A KR 850005776 A KR850005776 A KR 850005776A
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KR
South Korea
Prior art keywords
lorazepam
diphenhydramine
acid addition
addition salts
weight ratio
Prior art date
Application number
KR1019840007749A
Other languages
English (en)
Other versions
KR880002523B1 (ko
Inventor
삐다우어 요세프
Original Assignee
니콜라우스 훼리거,요세프 삐다우어
메디헤미 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 니콜라우스 훼리거,요세프 삐다우어, 메디헤미 악티엔게젤샤프트 filed Critical 니콜라우스 훼리거,요세프 삐다우어
Publication of KR850005776A publication Critical patent/KR850005776A/ko
Application granted granted Critical
Publication of KR880002523B1 publication Critical patent/KR880002523B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Developing Agents For Electrophotography (AREA)

Abstract

내용 없음

Description

로라제팜 함유 수면제 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 로라제팜, 디펜히드라민 또는 그의 산부가염 및 비약리학적으로 활성인 담체로 되고, 로라제팜대디펜히드라민 또는 그의 산부가염의 중량 비율이 1:10-1:75인 수면제.
  2. 제1항에 있어서, 상기 비율이 1:20-1:인 수면제.
  3. 로라제팜과 디펜히드라민 또는 디펜히드라민의 산부가염을, 로라제팜대 디펜히드라민 또는 그의 산부가염의 중량비율 1:10-1:75로 혼합시키고 이 혼합물을 경구 또는 직장투여에 적합한 형태로 제제시킴을 특징으로 하는 수면제의 제조방법.
  4. 제3항서에 있어, 상기 비율이 1:20-1-35인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019840007749A 1984-02-08 1984-12-07 로라제팜의 부작용을 감소시키는 방법 KR880002523B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3404316A DE3404316C1 (de) 1984-02-08 1984-02-08 Lorazepam-haltiges Schlafmittel
DE93404316.0 1984-02-08
DEP3404316.0 1984-02-08

Publications (2)

Publication Number Publication Date
KR850005776A true KR850005776A (ko) 1985-09-26
KR880002523B1 KR880002523B1 (ko) 1988-11-28

Family

ID=6227049

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840007749A KR880002523B1 (ko) 1984-02-08 1984-12-07 로라제팜의 부작용을 감소시키는 방법

Country Status (14)

Country Link
US (1) US4590191A (ko)
EP (1) EP0151245B1 (ko)
JP (1) JPS60174718A (ko)
KR (1) KR880002523B1 (ko)
AT (1) ATE56871T1 (ko)
AU (1) AU562271B2 (ko)
CA (1) CA1237078A (ko)
DE (2) DE3404316C1 (ko)
DK (1) DK551384A (ko)
ES (1) ES8608315A1 (ko)
GR (1) GR81060B (ko)
IE (1) IE57933B1 (ko)
PT (1) PT79647B (ko)
ZA (1) ZA849270B (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0930884B1 (de) * 1996-10-11 2002-12-18 Medichemie Ag Chronische verwendung von lorazepam und diphenhydramin
ITRM20020357A1 (it) * 2002-07-03 2004-01-05 Foscama Biomed Chim Farma Composizione liquida per la somministrazione orale di lorazepam.
US20080031944A1 (en) * 2006-08-04 2008-02-07 Cima Labs Inc. Stabilization of lorazepam

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2155832B1 (ko) * 1971-10-08 1975-08-01 Delalande Sa

Also Published As

Publication number Publication date
DK551384A (da) 1985-08-09
ATE56871T1 (de) 1990-10-15
EP0151245A2 (de) 1985-08-14
JPH0445493B2 (ko) 1992-07-27
AU3609384A (en) 1985-08-15
EP0151245B1 (de) 1990-09-26
CA1237078A (en) 1988-05-24
PT79647B (en) 1986-10-21
ZA849270B (en) 1985-07-31
KR880002523B1 (ko) 1988-11-28
GR81060B (en) 1985-05-20
DE3483318D1 (de) 1990-10-31
PT79647A (en) 1985-01-01
DE3404316C1 (de) 1985-06-20
DK551384D0 (da) 1984-11-20
ES538171A0 (es) 1986-06-16
EP0151245A3 (en) 1988-03-30
JPS60174718A (ja) 1985-09-09
IE843026L (en) 1985-08-08
ES8608315A1 (es) 1986-06-16
AU562271B2 (en) 1987-06-04
IE57933B1 (en) 1993-05-19
US4590191A (en) 1986-05-20

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