JPS5781411A - Medicinal composition having antiviral action - Google Patents

Medicinal composition having antiviral action

Info

Publication number
JPS5781411A
JPS5781411A JP55157971A JP15797180A JPS5781411A JP S5781411 A JPS5781411 A JP S5781411A JP 55157971 A JP55157971 A JP 55157971A JP 15797180 A JP15797180 A JP 15797180A JP S5781411 A JPS5781411 A JP S5781411A
Authority
JP
Japan
Prior art keywords
compound
formula
medicinal composition
antiviral action
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55157971A
Other languages
Japanese (ja)
Other versions
JPS5817167B2 (en
Inventor
Suguru Mochida
Yasuo Suzuki
Haruo Onishi
Kazuo Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Priority to JP55157971A priority Critical patent/JPS5817167B2/en
Priority to JP56096376A priority patent/JPS58914A/en
Priority to GB8133392A priority patent/GB2090136B/en
Priority to DE19813144689 priority patent/DE3144689A1/en
Priority to FR8121017A priority patent/FR2493702A1/en
Publication of JPS5781411A publication Critical patent/JPS5781411A/en
Priority to PCT/JP1982/000242 priority patent/WO1983000013A1/en
Priority to EP82105460A priority patent/EP0068408A1/en
Publication of JPS5817167B2 publication Critical patent/JPS5817167B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms

Abstract

PURPOSE: An antiviral agent, containing a 3-aminosulfonyl-4-halogenobenzoic acid or a salt thereof as an active constituent, and having very high safety.
CONSTITUTION: An antiviral agent containing a compound of the formula (X is halogen) or a salt thereof. The compound of the formula is very useful for treating the inflammation of the upper air passage, pneumonia, bronchitis, etc. For example, the remedy is used in the form of an oral, rectal administering agent or injection. The daily does thereof is usually about 10W5,000mg. The compound of the formula is obtained by chlorosulfonating a 4-halogenobenzoic acid with chlorosulfonic acid, and reacting the reaction product with ammonia.
COPYRIGHT: (C)1982,JPO&Japio
JP55157971A 1980-11-10 1980-11-10 Pharmaceutical composition with antiviral action Expired JPS5817167B2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP55157971A JPS5817167B2 (en) 1980-11-10 1980-11-10 Pharmaceutical composition with antiviral action
JP56096376A JPS58914A (en) 1980-11-10 1981-06-22 Medical composition with antiviral effect
GB8133392A GB2090136B (en) 1980-11-10 1981-11-05 Antiviral compositions containing sulphonamide derivatives
DE19813144689 DE3144689A1 (en) 1980-11-10 1981-11-10 ANTIVIRUS
FR8121017A FR2493702A1 (en) 1980-11-10 1981-11-10 ANTIVIRAL COMPOSITIONS CONTAINING AMINOSULFONYLHALOGENOBENZOIC ACID DERIVATIVES
PCT/JP1982/000242 WO1983000013A1 (en) 1980-11-10 1982-06-22 Medicinal composition having an antiviral effect
EP82105460A EP0068408A1 (en) 1980-11-10 1982-06-22 Antiviral compositions and a method for treating virus diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55157971A JPS5817167B2 (en) 1980-11-10 1980-11-10 Pharmaceutical composition with antiviral action
JP56096376A JPS58914A (en) 1980-11-10 1981-06-22 Medical composition with antiviral effect

Publications (2)

Publication Number Publication Date
JPS5781411A true JPS5781411A (en) 1982-05-21
JPS5817167B2 JPS5817167B2 (en) 1983-04-05

Family

ID=26437582

Family Applications (2)

Application Number Title Priority Date Filing Date
JP55157971A Expired JPS5817167B2 (en) 1980-11-10 1980-11-10 Pharmaceutical composition with antiviral action
JP56096376A Pending JPS58914A (en) 1980-11-10 1981-06-22 Medical composition with antiviral effect

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP56096376A Pending JPS58914A (en) 1980-11-10 1981-06-22 Medical composition with antiviral effect

Country Status (4)

Country Link
JP (2) JPS5817167B2 (en)
DE (1) DE3144689A1 (en)
FR (1) FR2493702A1 (en)
GB (1) GB2090136B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06508819A (en) * 1991-02-12 1994-10-06 ヘキスト・アクチェンゲゼルシャフト Arylsulfonylureas, processes for their preparation and their use as herbicides and growth regulators

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068408A1 (en) * 1980-11-10 1983-01-05 Mochida Pharmaceutical Co., Ltd. Antiviral compositions and a method for treating virus diseases
JPS58192820A (en) * 1982-05-06 1983-11-10 Mochida Pharmaceut Co Ltd Antiviral medicinal composition
EP0132540A1 (en) * 1981-06-22 1985-02-13 Mochida Pharmaceutical Co., Ltd. Antiviral compositions
DK315482A (en) * 1981-07-20 1983-01-21 Kimberly Clark Co PROCEDURE FOR PREVENTING DISTRIBUTION OF SPIRIT WIRES AND METHOD FOR USING THE PROCEDURE
JPS5878796A (en) * 1981-11-06 1983-05-12 Jujo Paper Co Ltd Thermal recording material
JPS6189887A (en) * 1984-10-09 1986-05-08 Hosokawa Katsupanshiyo:Kk Heat-transfer original paper
JPS61164893A (en) * 1985-01-17 1986-07-25 Matsushita Electric Ind Co Ltd Image-receiving material for transfer-type thermal recording
JPS61164892A (en) * 1985-01-17 1986-07-25 Matsushita Electric Ind Co Ltd Image-receiving material for transfer-type thermal recording
EP0197386B1 (en) * 1985-03-27 1988-11-02 Merck & Co. Inc. 2-(substituted sulfamyl) derivatives of 6-nitrobenzoic acid, process for their preparation and pharmaceutical compositions containing them
JPS61188866U (en) * 1985-05-16 1986-11-25
JPS62204988A (en) * 1986-03-06 1987-09-09 Teijin Ltd Raw paper for printing
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06508819A (en) * 1991-02-12 1994-10-06 ヘキスト・アクチェンゲゼルシャフト Arylsulfonylureas, processes for their preparation and their use as herbicides and growth regulators
JP2544566B2 (en) * 1991-02-12 1996-10-16 ヘキスト・アクチェンゲゼルシャフト Arylsulfonylureas, their method of manufacture and their use as herbicides and growth regulators

Also Published As

Publication number Publication date
FR2493702B1 (en) 1984-10-12
FR2493702A1 (en) 1982-05-14
DE3144689A1 (en) 1982-07-22
JPS58914A (en) 1983-01-06
JPS5817167B2 (en) 1983-04-05
GB2090136B (en) 1985-02-06
GB2090136A (en) 1982-07-07

Similar Documents

Publication Publication Date Title
JPS5781411A (en) Medicinal composition having antiviral action
JPS552601A (en) Anti-tumor agent for non-injection use
ES8300735A1 (en) Phenylalkanoic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them.
JPS5543077A (en) Preparation of 1,3-dithiolan-2-ylidenemalonate derivative
JPS52136159A (en) Anti/malignanttumor containing the same as active ingredients
EP0270046A3 (en) Pharmaceutical composition for treatment of cataract
JPS57118555A (en) Leucotriene-analog compound, its preparation, and leucotriene-biosynthesis inhibiting agent containing said compound as active component
JPS5239636A (en) Synthetic process of dihydrocoenzyme q group compound
ATE40948T1 (en) PYRIDYL ALKYL NITRATE COMPOUND, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING IT.
JPS54132520A (en) Preparation of colorless methionine
ES8308562A1 (en) Polycyclic compounds containing a double bond in the D-ring pharmaceutical compositions containing them, and methods of treating psoriasis with them
JPS5742620A (en) Novel antiulcer agent
AU562271B2 (en) Pharmaceutical composition of corazepam and diphenhydramine
JPS57106644A (en) Farnesence derivative, mucosa stabilizer comprising it as active ingredient, and its preparation
EP0382854A4 (en) Indoleacetic acid derivatives, process for their preparation, and medicines containing same as active ingredients
JPS5750969A (en) Preparation of 5-ureidohydantoin
JPS5344572A (en) 5-alkoxy-picolic acid, its preparation and hypotensives containing the same
JPS57171989A (en) Aminometyl-secalonic acid and its preparation
JPS5620572A (en) 4-tert-butylbenzamide derivative and antimicrobial containing the same
JPS5557571A (en) Novel 5-fluorouracil derivative
JPS5283585A (en) Novel penicillin derivatives
JPS5610176A (en) Novel nitrosourea, its preparation, and antitumor agent containing the same
JPS55167220A (en) Antitumor drug
JPS5651478A (en) 3-carbamoyl-pyrazolo 1,5-a pyridine and its preparation
JPS5219669A (en) Preparation of tetrazole derivatives and acid addition salts thereof