JPS55167220A - Antitumor drug - Google Patents
Antitumor drugInfo
- Publication number
- JPS55167220A JPS55167220A JP7546379A JP7546379A JPS55167220A JP S55167220 A JPS55167220 A JP S55167220A JP 7546379 A JP7546379 A JP 7546379A JP 7546379 A JP7546379 A JP 7546379A JP S55167220 A JPS55167220 A JP S55167220A
- Authority
- JP
- Japan
- Prior art keywords
- air
- tumors
- antitumor
- antitumor drug
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: An antitumor drug having improved stability in air, prepared by using an antitumor aldehyde in the form of a specified stable thiazolidine compound.
CONSTITUTION: An antitumor drug comprising as an active constitutent 2-phenyl thiazolidine-4-carboxylic acid, which is obtained as colorless needle-shaped crystals, melting point 158W160°C, slightly soluble in cold mater, and readily soluble in the water in the form of its neutral alkali salts, by reacting benzaldehyde with cysteine according to the well-known processes. Although aldehydes are generally oxidized readily and unstable in air, said compound is stable in the air. The great activity against solid tumors, along with said stability, renders the drug fit for various uses in the treatment of the tumors such as digestive and respiratory system tumors. The daily dose is preferably 25W400mg/kg.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7546379A JPS55167220A (en) | 1979-06-14 | 1979-06-14 | Antitumor drug |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7546379A JPS55167220A (en) | 1979-06-14 | 1979-06-14 | Antitumor drug |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55167220A true JPS55167220A (en) | 1980-12-26 |
JPS6327325B2 JPS6327325B2 (en) | 1988-06-02 |
Family
ID=13577017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7546379A Granted JPS55167220A (en) | 1979-06-14 | 1979-06-14 | Antitumor drug |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55167220A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57128625A (en) * | 1981-01-30 | 1982-08-10 | Rikagaku Kenkyusho | Carcinostatic |
US5169858A (en) * | 1984-12-18 | 1992-12-08 | David Rubin | Anti-tumor compositions containing the reactive product of benzaldehyde or salicylaldehyde with penicillamine and method of use thereof |
-
1979
- 1979-06-14 JP JP7546379A patent/JPS55167220A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57128625A (en) * | 1981-01-30 | 1982-08-10 | Rikagaku Kenkyusho | Carcinostatic |
US5169858A (en) * | 1984-12-18 | 1992-12-08 | David Rubin | Anti-tumor compositions containing the reactive product of benzaldehyde or salicylaldehyde with penicillamine and method of use thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS6327325B2 (en) | 1988-06-02 |
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