JPS5233682A - Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil - Google Patents

Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil

Info

Publication number
JPS5233682A
JPS5233682A JP10853275A JP10853275A JPS5233682A JP S5233682 A JPS5233682 A JP S5233682A JP 10853275 A JP10853275 A JP 10853275A JP 10853275 A JP10853275 A JP 10853275A JP S5233682 A JPS5233682 A JP S5233682A
Authority
JP
Japan
Prior art keywords
flurouracil
tetrahydrofuryl
bis
preparation
halogenotetrahydrofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10853275A
Other languages
Japanese (ja)
Other versions
JPS5323315B2 (en
Inventor
Shoichiro Ozaki
Haruo Mizuno
Katsutoshi Ishikawa
Haruki Mori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP10853275A priority Critical patent/JPS5233682A/en
Publication of JPS5233682A publication Critical patent/JPS5233682A/en
Publication of JPS5323315B2 publication Critical patent/JPS5323315B2/ja
Granted legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: Title compound useful as intermediate for the synthesis of carcinostatic agents is prepared by the reaction of 5-fluorouracil with 2-halogenotetrahydrofuran in the presence of a base.
COPYRIGHT: (C)1977,JPO&Japio
JP10853275A 1975-09-09 1975-09-09 Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil Granted JPS5233682A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10853275A JPS5233682A (en) 1975-09-09 1975-09-09 Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10853275A JPS5233682A (en) 1975-09-09 1975-09-09 Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3722176A Division JPS5233683A (en) 1976-04-05 1976-04-05 Preparation of 1-(2'-tetrahydrofuryl)-5-flurouracil

Publications (2)

Publication Number Publication Date
JPS5233682A true JPS5233682A (en) 1977-03-14
JPS5323315B2 JPS5323315B2 (en) 1978-07-13

Family

ID=14487181

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10853275A Granted JPS5233682A (en) 1975-09-09 1975-09-09 Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil

Country Status (1)

Country Link
JP (1) JPS5233682A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5289679A (en) * 1976-01-19 1977-07-27 Takeda Chem Ind Ltd Preparation of 5-fluorouracil derivatives
JPS53108988A (en) * 1977-03-04 1978-09-22 Takeda Chem Ind Ltd Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5525301A (en) * 1978-08-11 1980-02-23 Bando Chem Ind Ltd Rotary stamp
JPS5558354U (en) * 1978-10-16 1980-04-21
JPS55102558U (en) * 1979-01-12 1980-07-17

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49127981A (en) * 1973-04-20 1974-12-07
JPS5050384A (en) * 1973-09-05 1975-05-06
JPS5152182A (en) * 1974-10-11 1976-05-08 Mitsui Seiyaku Kogyo Kk 11 * 22 tetorahidorofuriru * urashiruruino seizoho

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS49127981A (en) * 1973-04-20 1974-12-07
JPS5050384A (en) * 1973-09-05 1975-05-06
JPS5152182A (en) * 1974-10-11 1976-05-08 Mitsui Seiyaku Kogyo Kk 11 * 22 tetorahidorofuriru * urashiruruino seizoho

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5289679A (en) * 1976-01-19 1977-07-27 Takeda Chem Ind Ltd Preparation of 5-fluorouracil derivatives
JPS5412474B2 (en) * 1976-01-19 1979-05-23
JPS53108988A (en) * 1977-03-04 1978-09-22 Takeda Chem Ind Ltd Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
JPS5420509B2 (en) * 1977-03-04 1979-07-23

Also Published As

Publication number Publication date
JPS5323315B2 (en) 1978-07-13

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