JPS532479A - Synthesis of n-substituted uracils - Google Patents

Synthesis of n-substituted uracils

Info

Publication number
JPS532479A
JPS532479A JP7571376A JP7571376A JPS532479A JP S532479 A JPS532479 A JP S532479A JP 7571376 A JP7571376 A JP 7571376A JP 7571376 A JP7571376 A JP 7571376A JP S532479 A JPS532479 A JP S532479A
Authority
JP
Japan
Prior art keywords
synthesis
substituted uracils
uracils
substituted
dihydrofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7571376A
Other languages
Japanese (ja)
Inventor
Toshio Nakamura
Yasuo Hoshiide
Yoshio Hashimoto
Kenichi Suzuki
Yoji Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIKKEN KAGAKU KK
Nikken Chemicals Co Ltd
Original Assignee
NIKKEN KAGAKU KK
Nikken Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIKKEN KAGAKU KK, Nikken Chemicals Co Ltd filed Critical NIKKEN KAGAKU KK
Priority to JP7571376A priority Critical patent/JPS532479A/en
Priority to US05/774,050 priority patent/US4121037A/en
Priority to DE19772709838 priority patent/DE2709838A1/en
Priority to FI770742A priority patent/FI770742A/fi
Priority to NL7702515A priority patent/NL7702515A/en
Priority to FR7707138A priority patent/FR2360589A1/en
Priority to NO770856A priority patent/NO770856L/en
Priority to GB10209/77A priority patent/GB1577527A/en
Priority to SE7702796A priority patent/SE7702796L/en
Priority to DK107877A priority patent/DK107877A/en
Publication of JPS532479A publication Critical patent/JPS532479A/en
Pending legal-status Critical Current

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Abstract

PURPOSE: To prepare N-substituted uracils, useful as low toxicity carcinostatic agent for oral use, in good yield by reaction of uracils with 2, 3-dihydrofuran in the presence of a base and acid.
COPYRIGHT: (C)1978,JPO&Japio
JP7571376A 1976-06-26 1976-06-26 Synthesis of n-substituted uracils Pending JPS532479A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP7571376A JPS532479A (en) 1976-06-26 1976-06-26 Synthesis of n-substituted uracils
US05/774,050 US4121037A (en) 1976-06-26 1977-03-03 Process for producing 5-fluorouracil derivative with a calcium chloride catalyst
DE19772709838 DE2709838A1 (en) 1976-06-26 1977-03-07 PROCESS FOR THE PREPARATION OF 5-FLUORURACIL DERIVATIVES WITH A CATALYST
FI770742A FI770742A (en) 1976-06-26 1977-03-08
NL7702515A NL7702515A (en) 1976-06-26 1977-03-09 PROCEDURE FOR PREPARING A 5-FLUORURACIL DERIVATIVE.
FR7707138A FR2360589A1 (en) 1976-06-26 1977-03-10 PROCESS FOR THE PRODUCTION OF 5-FLUOROURACIL DERIVATIVES IN THE PRESENCE OF A CATALYST
NO770856A NO770856L (en) 1976-06-26 1977-03-10 PROCEDURES FOR THE PREPARATION OF 5-FLUORURACIL DERIVATIVES
GB10209/77A GB1577527A (en) 1976-06-26 1977-03-10 Process for producing 5-fluorouracil derivative with a catalyst
SE7702796A SE7702796L (en) 1976-06-26 1977-03-11 PROCEDURE FOR PREPARING 5-FLUOROURACIL DERIVATIVES WITH A CATALYST
DK107877A DK107877A (en) 1976-06-26 1977-03-11 PROCEDURE FOR THE PREPARATION OF A 5-FLUORURACIL DERIVATIVE USING A CATALYST

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7571376A JPS532479A (en) 1976-06-26 1976-06-26 Synthesis of n-substituted uracils

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP3808878A Division JPS53121771A (en) 1978-04-03 1978-04-03 Preparation of n-substitured uracils

Publications (1)

Publication Number Publication Date
JPS532479A true JPS532479A (en) 1978-01-11

Family

ID=13584149

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7571376A Pending JPS532479A (en) 1976-06-26 1976-06-26 Synthesis of n-substituted uracils

Country Status (1)

Country Link
JP (1) JPS532479A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5289678A (en) * 1976-01-09 1977-07-27 Mitsui Toatsu Chem Inc Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5289678A (en) * 1976-01-09 1977-07-27 Mitsui Toatsu Chem Inc Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil

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