JPS5289678A - Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil - Google Patents

Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil

Info

Publication number
JPS5289678A
JPS5289678A JP160076A JP160076A JPS5289678A JP S5289678 A JPS5289678 A JP S5289678A JP 160076 A JP160076 A JP 160076A JP 160076 A JP160076 A JP 160076A JP S5289678 A JPS5289678 A JP S5289678A
Authority
JP
Japan
Prior art keywords
fluorouracil
tetrahydrofuryl
preparation
antivirial
dihydrofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP160076A
Other languages
Japanese (ja)
Other versions
JPS5324079B2 (en
Inventor
Atsushi Kojima
Yoshitsugu Jinno
Yoshimasa Ike
Tatsuro Yokoyama
Makoto Odate
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Priority to JP160076A priority Critical patent/JPS5289678A/en
Priority to DK539376AA priority patent/DK142415B/en
Priority to NO764136A priority patent/NO145575C/en
Priority to SE7613751A priority patent/SE7613751L/en
Priority to GB50989/76A priority patent/GB1522860A/en
Priority to CA267,561A priority patent/CA1114376A/en
Priority to US05/749,433 priority patent/US4256885A/en
Priority to DE2656604A priority patent/DE2656604C3/en
Priority to PH19272A priority patent/PH15812A/en
Priority to NL7614220A priority patent/NL7614220A/en
Priority to FI763665A priority patent/FI63758C/en
Priority to PT66013A priority patent/PT66013B/en
Priority to AT961176A priority patent/AT347477B/en
Priority to FR7638941A priority patent/FR2336401A1/en
Priority to CH1631676A priority patent/CH623583A5/de
Publication of JPS5289678A publication Critical patent/JPS5289678A/en
Publication of JPS5324079B2 publication Critical patent/JPS5324079B2/ja
Granted legal-status Critical Current

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  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PURPOSE: To obtain 1 - (2 - tetrahydrofuryl) - 5 - fluorouracil useful as antitumor and antivirial agents, by the reaction of 5 - fluorouracil upon 2, 3 dihydrofuran in the presence of a specific compound.
COPYRIGHT: (C)1977,JPO&Japio
JP160076A 1975-12-24 1976-01-09 Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil Granted JPS5289678A (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
JP160076A JPS5289678A (en) 1976-01-09 1976-01-09 Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
DK539376AA DK142415B (en) 1975-12-24 1976-11-30 Process for the preparation of 1- (2-tetrahydrofuryl) -5-fluorouracil.
NO764136A NO145575C (en) 1975-12-24 1976-12-03 PROCEDURE FOR PREPARING 1- (2'-TETRAHYDROFURYL) -5-FLUORURACIL
SE7613751A SE7613751L (en) 1975-12-24 1976-12-07 PROCEDURE FOR THE PREPARATION OF 1- (2-TETRAHYDROFURYL) -5-FLUOROURACIL
GB50989/76A GB1522860A (en) 1975-12-24 1976-12-07 Process for the preparation of 1 - (2-tetrahydrofuryl) - 5 - fluorouracil
CA267,561A CA1114376A (en) 1975-12-24 1976-12-09 Process for the preparation of 1-(2-tetrahydrofuryl)- 5-fluorouracil
US05/749,433 US4256885A (en) 1975-12-24 1976-12-10 Process for the preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
DE2656604A DE2656604C3 (en) 1975-12-24 1976-12-14 Process for the preparation of 1 - (2-tetrahydrofuryl) -5-fluoro-uracil
PH19272A PH15812A (en) 1975-12-24 1976-12-21 Process for the preparation of 1-(2-tetrahydrofuryl)5-fluorouracil
NL7614220A NL7614220A (en) 1975-12-24 1976-12-21 PROCESS FOR THE PREPARATION OF 1- (2-TETRAHYDRO-FURYL) -5-FLUORURACIL.
FI763665A FI63758C (en) 1975-12-24 1976-12-21 REFRIGERATION FOR FRAMSTAELLNING AV 1- (2-TETRAHYDROFURYL) -5-FLUORURACIL
PT66013A PT66013B (en) 1975-12-24 1976-12-23 Process for the preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil
AT961176A AT347477B (en) 1975-12-24 1976-12-23 METHOD FOR PRODUCING 1- (2- TETRAHYDROFURYL) -5-FLUOROURACIL
FR7638941A FR2336401A1 (en) 1975-12-24 1976-12-23 PROCESS FOR THE PREPARATION OF 1- (2-TETRAHYDROFURYL) -5-FLUOROURACIL
CH1631676A CH623583A5 (en) 1975-12-24 1976-12-24

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP160076A JPS5289678A (en) 1976-01-09 1976-01-09 Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil

Publications (2)

Publication Number Publication Date
JPS5289678A true JPS5289678A (en) 1977-07-27
JPS5324079B2 JPS5324079B2 (en) 1978-07-18

Family

ID=11505984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP160076A Granted JPS5289678A (en) 1975-12-24 1976-01-09 Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil

Country Status (1)

Country Link
JP (1) JPS5289678A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532479A (en) * 1976-06-26 1978-01-11 Nikken Kagaku Kk Synthesis of n-substituted uracils
JPS545986A (en) * 1978-04-06 1979-01-17 Wakamoto Pharma Co Ltd Production of n11*22 tetrhydrofuryl**55 fluorouracil

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5019757A (en) * 1973-06-23 1975-03-01
JPS5064281A (en) * 1973-10-15 1975-05-31
JPS50142717A (en) * 1974-05-10 1975-11-17
JPS5165753A (en) * 1974-12-05 1976-06-07 Kojin Kk 22 ashiruokishitetorahidorofuranruino seizohoho
JPS5268188A (en) * 1975-11-28 1977-06-06 Takeda Chem Ind Ltd Preparation of 1-(tetrahydro-2-furyl)-5-fluorouracil

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5019757A (en) * 1973-06-23 1975-03-01
JPS5064281A (en) * 1973-10-15 1975-05-31
JPS50142717A (en) * 1974-05-10 1975-11-17
JPS5165753A (en) * 1974-12-05 1976-06-07 Kojin Kk 22 ashiruokishitetorahidorofuranruino seizohoho
JPS5268188A (en) * 1975-11-28 1977-06-06 Takeda Chem Ind Ltd Preparation of 1-(tetrahydro-2-furyl)-5-fluorouracil

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS532479A (en) * 1976-06-26 1978-01-11 Nikken Kagaku Kk Synthesis of n-substituted uracils
JPS545986A (en) * 1978-04-06 1979-01-17 Wakamoto Pharma Co Ltd Production of n11*22 tetrhydrofuryl**55 fluorouracil
JPS5532712B2 (en) * 1978-04-06 1980-08-26

Also Published As

Publication number Publication date
JPS5324079B2 (en) 1978-07-18

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