JPS5268189A - Preparation of pyrimidine-type nucleosides - Google Patents

Preparation of pyrimidine-type nucleosides

Info

Publication number
JPS5268189A
JPS5268189A JP50144637A JP14463775A JPS5268189A JP S5268189 A JPS5268189 A JP S5268189A JP 50144637 A JP50144637 A JP 50144637A JP 14463775 A JP14463775 A JP 14463775A JP S5268189 A JPS5268189 A JP S5268189A
Authority
JP
Japan
Prior art keywords
pyrimidine
preparation
type nucleosides
nucleosides
type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP50144637A
Other languages
Japanese (ja)
Other versions
JPS5337873B2 (en
Inventor
Masanao Matsui
Tomoya Ogawa
Takashi Kono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RIKEN Institute of Physical and Chemical Research
Original Assignee
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RIKEN Institute of Physical and Chemical Research filed Critical RIKEN Institute of Physical and Chemical Research
Priority to JP50144637A priority Critical patent/JPS5268189A/en
Priority to DE2660197A priority patent/DE2660197C3/en
Priority to DE2648239A priority patent/DE2648239C3/en
Priority to US05/735,777 priority patent/US4324895A/en
Publication of JPS5268189A publication Critical patent/JPS5268189A/en
Publication of JPS5337873B2 publication Critical patent/JPS5337873B2/ja
Priority to US06/287,642 priority patent/US4447605A/en
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/22Tin compounds
    • C07F7/2224Compounds having one or more tin-oxygen linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Abstract

PURPOSE: To prepare title compounds useful as carcinostatic agents, etc. in good yield from novel derivatives of bis (tri-n-lower alkyltin)-5-halogenouracil and 2subst. tetrahydrofurans.
COPYRIGHT: (C)1977,JPO&Japio
JP50144637A 1975-10-24 1975-12-04 Preparation of pyrimidine-type nucleosides Granted JPS5268189A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP50144637A JPS5268189A (en) 1975-12-04 1975-12-04 Preparation of pyrimidine-type nucleosides
DE2660197A DE2660197C3 (en) 1975-12-04 1976-10-25 3- (2-Tetrahydrofuranyl) -5-fluorouracil and its use in combating malignant neoplasms
DE2648239A DE2648239C3 (en) 1975-10-24 1976-10-25 Di (trialkylstannyl) pyrimidine derivatives, processes for their preparation and processes for their further processing into nucleoside-like pyrimidine derivatives
US05/735,777 US4324895A (en) 1975-12-04 1976-10-28 Novel process for producing pyrimidine nucleosides and novel pyrimidine nucleosides obtained thereby
US06/287,642 US4447605A (en) 1975-10-24 1981-07-28 Di(tri-lower alkylstannyl)pyrimidine derivative and a process for producing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50144637A JPS5268189A (en) 1975-12-04 1975-12-04 Preparation of pyrimidine-type nucleosides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP5346376A Division JPS5268190A (en) 1975-10-24 1976-05-11 Preparation of pyrimidine-type nucleosides

Publications (2)

Publication Number Publication Date
JPS5268189A true JPS5268189A (en) 1977-06-06
JPS5337873B2 JPS5337873B2 (en) 1978-10-12

Family

ID=15366681

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50144637A Granted JPS5268189A (en) 1975-10-24 1975-12-04 Preparation of pyrimidine-type nucleosides

Country Status (2)

Country Link
JP (1) JPS5268189A (en)
DE (1) DE2660197C3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5359682A (en) * 1976-10-25 1978-05-29 Rikagaku Kenkyusho Uracil compounds

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4910510A (en) * 1972-05-30 1974-01-30
JPS5019757A (en) * 1973-06-23 1975-03-01
JPS5050383A (en) * 1973-09-05 1975-05-06
JPS50105674A (en) * 1974-01-25 1975-08-20
JPS5251373A (en) * 1975-10-24 1977-04-25 Rikagaku Kenkyusho Preparaton of pyrmidine ucleosides
JPS5323316A (en) * 1976-08-16 1978-03-03 Ota Toshuki Method of moulding mass of short staple

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4910510A (en) * 1972-05-30 1974-01-30
JPS5019757A (en) * 1973-06-23 1975-03-01
JPS5050383A (en) * 1973-09-05 1975-05-06
JPS50105674A (en) * 1974-01-25 1975-08-20
JPS5251373A (en) * 1975-10-24 1977-04-25 Rikagaku Kenkyusho Preparaton of pyrmidine ucleosides
JPS5323316A (en) * 1976-08-16 1978-03-03 Ota Toshuki Method of moulding mass of short staple

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5359682A (en) * 1976-10-25 1978-05-29 Rikagaku Kenkyusho Uracil compounds
JPS5420510B2 (en) * 1976-10-25 1979-07-23

Also Published As

Publication number Publication date
DE2660197B2 (en) 1981-07-09
DE2660197C3 (en) 1982-03-25
JPS5337873B2 (en) 1978-10-12

Similar Documents

Publication Publication Date Title
JPS5277073A (en) 1-carbamoyl-5-fluorouracil deruvative and anticancer drug containing s ame as effective component
JPS5268189A (en) Preparation of pyrimidine-type nucleosides
JPS5233682A (en) Preparation of 1,3-bis(2'-tetrahydrofuryl)-5-flurouracil
JPS5227783A (en) Preparation of unsaturated nucleosides
JPS5268190A (en) Preparation of pyrimidine-type nucleosides
JPS5231051A (en) Preparation of amino sugar derivatives
JPS5386094A (en) Preparation of 7-amino-cephem derivatives
JPS5251373A (en) Preparaton of pyrmidine ucleosides
JPS5248677A (en) Preparation of pyrimidine derivatives
JPS5432487A (en) Preparation of 1-carbamoyluracils
JPS5321170A (en) Preparation of branched 2-deoxy-alpha-glycosides
JPS5259112A (en) Process for preparation of delta-substituted negamycine derivatives
JPS5279090A (en) Preparation of powdered soy sauce
JPS5225782A (en) Preparation of cytidine derivatives
JPS5283385A (en) Synthesis of n1-(2,-furanidyl)-5-flurouracil
JPS5231079A (en) Preparation of uracil derivatives
JPS5283421A (en) Preparation of phenoxypropylamine derivatives
JPS5265281A (en) Preparation of n4-dimethylamino methylene-arabinofuranosil cytosine
JPS5251362A (en) Preparation of optically active pyrrolidine derivatives
JPS5278886A (en) Synthesis of 5-fluorouracil derivatives
JPS525782A (en) Preparation of 1-phthalazinone
JPS53144585A (en) Novel uracil derivative and process for its preparation
JPS5251374A (en) Preparation of pyrimidine nucleosides
JPS5214752A (en) Preparation of 2-hydroxy-4-alkadienyloxy -benzophenones
JPS5273847A (en) Preparation of 4-homoisotwistane-3-carboxylic acid