JPS57128625A - Carcinostatic - Google Patents

Carcinostatic

Info

Publication number
JPS57128625A
JPS57128625A JP1261281A JP1261281A JPS57128625A JP S57128625 A JPS57128625 A JP S57128625A JP 1261281 A JP1261281 A JP 1261281A JP 1261281 A JP1261281 A JP 1261281A JP S57128625 A JPS57128625 A JP S57128625A
Authority
JP
Japan
Prior art keywords
carcinostatic
active ingredient
injection
case
compound shown
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1261281A
Other languages
Japanese (ja)
Inventor
Setsuo Takeuchi
Mutsuyuki Kochi
Akira Kawarada
Shinichiro Esumi
Kazuya Sasaki
Shozo Kawabata
Tsuneo Saida
Masao Sakasai
Yukio Inoue
Tadasu Yamamoto
Ban Sanai
Takaharu Sekine
Koji Amamiya
Katsumasa Saga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
RIKEN Institute of Physical and Chemical Research
Original Assignee
Kaken Pharmaceutical Co Ltd
Kaken Chemical Co Ltd
RIKEN Institute of Physical and Chemical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd, Kaken Chemical Co Ltd, RIKEN Institute of Physical and Chemical Research filed Critical Kaken Pharmaceutical Co Ltd
Priority to JP1261281A priority Critical patent/JPS57128625A/en
Publication of JPS57128625A publication Critical patent/JPS57128625A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: A carcinostatic having low toxicity and specifically carcinostatic activity, comprising a specific 4-thiazolidinecarboxylic acid compound as active ingredient.
CONSTITUTION: The titled carcinostatic comprising a compound shown by the formula (R is substituted naphtyl, phenyl, substituted phenyl, etc.; n is 1 or 2), or its salt as an active ingredient. Pharmaceutically manufactured into a capsule, tablet, injection, drops, etc., which is medicated orally or parenterally. The compound shown bythe formula exhibits high activity on SV40 induced cancer, which may be regarded as initially induced artificial cancer. A dose per adult a day is about 0.5W5,000mg/kg in case of oral medication, and in case of injection medication, its upper limit is about 100mg/kg.
COPYRIGHT: (C)1982,JPO&Japio
JP1261281A 1981-01-30 1981-01-30 Carcinostatic Pending JPS57128625A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1261281A JPS57128625A (en) 1981-01-30 1981-01-30 Carcinostatic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1261281A JPS57128625A (en) 1981-01-30 1981-01-30 Carcinostatic

Publications (1)

Publication Number Publication Date
JPS57128625A true JPS57128625A (en) 1982-08-10

Family

ID=11810185

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1261281A Pending JPS57128625A (en) 1981-01-30 1981-01-30 Carcinostatic

Country Status (1)

Country Link
JP (1) JPS57128625A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169858A (en) * 1984-12-18 1992-12-08 David Rubin Anti-tumor compositions containing the reactive product of benzaldehyde or salicylaldehyde with penicillamine and method of use thereof
US20170226070A1 (en) * 2013-03-15 2017-08-10 Cancer Research Technology, Llc Methods and compositions for gamma-glutamyl cycle modulation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2208533A1 (en) * 1972-02-23 1973-09-27 Kolmar Laboratories Long chain alkyl thioethers - surfactants, bacteriostats fungistats and anticancer agents
JPS55115822A (en) * 1978-12-21 1980-09-06 Gosalvez Mario Tumor treating agent and its manufacture
JPS55167220A (en) * 1979-06-14 1980-12-26 Senjiyu Seiyaku Kk Antitumor drug
JPS56133216A (en) * 1980-03-24 1981-10-19 Senjiyu Seiyaku Kk Antitumor agent

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2208533A1 (en) * 1972-02-23 1973-09-27 Kolmar Laboratories Long chain alkyl thioethers - surfactants, bacteriostats fungistats and anticancer agents
JPS55115822A (en) * 1978-12-21 1980-09-06 Gosalvez Mario Tumor treating agent and its manufacture
JPS55167220A (en) * 1979-06-14 1980-12-26 Senjiyu Seiyaku Kk Antitumor drug
JPS56133216A (en) * 1980-03-24 1981-10-19 Senjiyu Seiyaku Kk Antitumor agent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169858A (en) * 1984-12-18 1992-12-08 David Rubin Anti-tumor compositions containing the reactive product of benzaldehyde or salicylaldehyde with penicillamine and method of use thereof
US20170226070A1 (en) * 2013-03-15 2017-08-10 Cancer Research Technology, Llc Methods and compositions for gamma-glutamyl cycle modulation
US10323009B2 (en) * 2013-03-15 2019-06-18 Cancer Research Techology, Llp Methods and compositions for gamma-glutamyl cycle modulation

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