ES8801636A1 - Un procedimiento para preparar nuevos derivados de imidazol - Google Patents

Un procedimiento para preparar nuevos derivados de imidazol

Info

Publication number
ES8801636A1
ES8801636A1 ES557436A ES557436A ES8801636A1 ES 8801636 A1 ES8801636 A1 ES 8801636A1 ES 557436 A ES557436 A ES 557436A ES 557436 A ES557436 A ES 557436A ES 8801636 A1 ES8801636 A1 ES 8801636A1
Authority
ES
Spain
Prior art keywords
preparation
therapeutic use
imidazole derivatives
thromboxane
prophylaxis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557436A
Other languages
English (en)
Other versions
ES557436A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES557436A0 publication Critical patent/ES557436A0/es
Publication of ES8801636A1 publication Critical patent/ES8801636A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE IMIDAZOL, DE FORMULA GENERAL (I), SUS ESTERES, SUS AMIDAS Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. COMPRENDE LAS ETAPAS DE HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II) CON UN COMPUESTO DE FORMULA GENERAL (III), EN UN DISOLVENTE QUE NO AFECTA ADVERSAMENTE A LA REACCION A UNA TEMPERATURA COMPRENDIDA ENTRE C10 Y 100 GRADOS; DE OXIDAR EL COMPUESTO OBTENIDO CON UN AGENTE OXIDANTE CAPAZ DE TRANSFORMAR LA FUNCION -SEN LA FUNCION -SOO -SO2DEL TIPO DE UN PERACIDO ORGANICO Y EN UN DISOLVENTE QUE NO AFECTE ADVERSAMENTE A LA REACCION; Y DE TRANSFORMAR EL GRUPO R3FCARBOXILO EN UN GRUPO ESTER, AMIDA O EN UNA SAL. DE APLICACION EN EL TRATAMIENTO O PROFILAXIS DE LOS ESTADOS TROMBOTICOS.
ES557436A 1985-01-16 1987-03-05 Un procedimiento para preparar nuevos derivados de imidazol Expired ES8801636A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP405585 1985-01-16

Publications (2)

Publication Number Publication Date
ES557436A0 ES557436A0 (es) 1988-02-16
ES8801636A1 true ES8801636A1 (es) 1988-02-16

Family

ID=11574190

Family Applications (2)

Application Number Title Priority Date Filing Date
ES550972A Expired ES8706125A1 (es) 1985-01-16 1986-01-16 Un procedimiento para preparar nuevos derivados de imidiazol.
ES557436A Expired ES8801636A1 (es) 1985-01-16 1987-03-05 Un procedimiento para preparar nuevos derivados de imidazol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES550972A Expired ES8706125A1 (es) 1985-01-16 1986-01-16 Un procedimiento para preparar nuevos derivados de imidiazol.

Country Status (13)

Country Link
US (1) US4894385A (es)
EP (1) EP0188383B1 (es)
JP (1) JPH0625141B2 (es)
KR (1) KR930004674B1 (es)
AT (1) ATE104967T1 (es)
AU (1) AU582206B2 (es)
CA (1) CA1296009C (es)
DE (1) DE3689807T2 (es)
DK (1) DK20886A (es)
ES (2) ES8706125A1 (es)
FI (1) FI90866C (es)
NO (1) NO166445C (es)
ZA (1) ZA86286B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925953A (en) * 1987-12-09 1990-05-15 Ss Pharmaceutical Co., Ltd. Imidazole derivative
US5308860A (en) * 1993-01-15 1994-05-03 Rohm And Haas Company Cyanosulfonylethyltriazoles
JP2002167378A (ja) 2000-09-22 2002-06-11 Ss Pharmaceut Co Ltd イミダゾール誘導体又はその塩
JP2006347882A (ja) * 2003-09-02 2006-12-28 Ss Pharmaceut Co Ltd ベンジルアルコール誘導体又はその塩

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860862D1 (en) * 1977-10-13 1981-10-29 Siegfried Ag Imidazolylethylene-oxyalkyloxy derivatives and their thio analogues, methods for their preparation and pharmaceutical compositions containing them
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
DK471479A (da) * 1978-12-13 1980-06-14 Pfizer Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
JPS56120670A (en) * 1980-02-27 1981-09-22 Teijin Ltd 1-substituted imidazole derivative and its preparation
GB8400254D0 (en) * 1984-01-06 1984-02-08 Searle & Co Substituted alklidene imidazoles

Also Published As

Publication number Publication date
ATE104967T1 (de) 1994-05-15
EP0188383A2 (en) 1986-07-23
ZA86286B (en) 1986-09-24
FI90866C (fi) 1994-04-11
FI860210A0 (fi) 1986-01-16
NO166445B (no) 1991-04-15
NO166445C (no) 1991-08-07
ES550972A0 (es) 1987-06-01
JPH0625141B2 (ja) 1994-04-06
US4894385A (en) 1990-01-16
KR930004674B1 (ko) 1993-06-03
ES8706125A1 (es) 1987-06-01
CA1296009C (en) 1992-02-18
ES557436A0 (es) 1988-02-16
DE3689807D1 (de) 1994-06-01
FI90866B (fi) 1993-12-31
KR860005793A (ko) 1986-08-13
EP0188383A3 (en) 1988-06-22
JPS61267557A (ja) 1986-11-27
NO860114L (no) 1986-07-17
EP0188383B1 (en) 1994-04-27
AU582206B2 (en) 1989-03-16
DK20886D0 (da) 1986-01-16
FI860210A (fi) 1986-07-17
DK20886A (da) 1986-07-17
DE3689807T2 (de) 1994-08-25
AU5242586A (en) 1986-07-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001