ES8707249A1 - Un procedimiento para preparar derivados de fosfina y oro - Google Patents

Un procedimiento para preparar derivados de fosfina y oro

Info

Publication number
ES8707249A1
ES8707249A1 ES555089A ES555089A ES8707249A1 ES 8707249 A1 ES8707249 A1 ES 8707249A1 ES 555089 A ES555089 A ES 555089A ES 555089 A ES555089 A ES 555089A ES 8707249 A1 ES8707249 A1 ES 8707249A1
Authority
ES
Spain
Prior art keywords
phenyl
same
gold compounds
phosphine gold
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555089A
Other languages
English (en)
Other versions
ES555089A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/812,230 external-priority patent/US4675427A/en
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES8707249A1 publication Critical patent/ES8707249A1/es
Publication of ES555089A0 publication Critical patent/ES555089A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/50—Organo-phosphines
    • C07F9/5045—Complexes or chelates of phosphines with metallic compounds or metals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE FOSFINA Y ORO. COMPRENDE: A) HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON TETRAHIDRATO DE ACIDO CLOROAURICO, PARA PREPARAR UN COMPUESTO DE FORMULA (III); B) TRATAR AL COMPUESTO DE FORMULA (III) CON UN COMPUESTO DE FORMULA (IV), EN ACETONA, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R, FENILO; RK, FENILO; A, CADENA ALCANILOILO LINEAL O RAMIFICADO DE C 1 A 5; X, CL O BR; Y N, 1. SE UTILIZAN COMO INHIBIDORES DEL CRECIMIENTO TUMORAL.
ES555089A 1985-05-20 1986-05-19 Un procedimiento para preparar derivados de fosfina y oro Expired ES8707249A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73600185A 1985-05-20 1985-05-20
US73600385A 1985-05-20 1985-05-20
US06/812,230 US4675427A (en) 1985-05-20 1985-12-23 Tetraphosphine-coordinated gold(I) complexes

Publications (2)

Publication Number Publication Date
ES8707249A1 true ES8707249A1 (es) 1987-07-16
ES555089A0 ES555089A0 (es) 1987-07-16

Family

ID=27419206

Family Applications (1)

Application Number Title Priority Date Filing Date
ES555089A Expired ES8707249A1 (es) 1985-05-20 1986-05-19 Un procedimiento para preparar derivados de fosfina y oro

Country Status (5)

Country Link
EP (1) EP0202854A3 (es)
DK (1) DK230286A (es)
ES (1) ES8707249A1 (es)
FI (1) FI862087A (es)
NO (1) NO861961L (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8704181A1 (es) * 1985-01-22 1987-03-16 Smithkline Beckman Corp Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1238854A (en) * 1984-02-01 1988-07-05 David T. Hill ANTITUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING ¬.alpha.,W- BIS(DISUBSTITUTEDPHOSPHINO)HYDROCARBON| DIGOLD (I) DIGOLD (III), DISILVER (I) AND DICOPPER (I) DERIVATIVES
CA1244764A (en) * 1984-06-04 1988-11-15 Randall K. Johnson Tumor cell growth-inhibiting pharmaceutical compositions containing phosphino-hydrocarbon-gold, silver or copper complexes

Also Published As

Publication number Publication date
DK230286A (da) 1986-11-21
DK230286D0 (da) 1986-05-16
FI862087A (fi) 1986-11-21
EP0202854A2 (en) 1986-11-26
FI862087A0 (fi) 1986-05-19
EP0202854A3 (en) 1988-01-13
NO861961L (no) 1986-11-21
ES555089A0 (es) 1987-07-16

Similar Documents

Publication Publication Date Title
ES8701707A1 (es) Procedimiento para preparar derivados del acido acrilico conactividad fungicida
IL81002A (en) 3,4-diphenyl-pyrazoline-1-carboxamide derivatives,processes for the preparation thereof and insecticidal and acaricidal compositions containing the same
IL73093A0 (en) 1-methylamino-cyclopropane-1-carboxylic acid derivatives,their preparation and their use as plant growth regulators
HUT39328A (en) Fungicides and compositions regulating the growth of plants containing as reagent derivatives of azolil-methil-cycloprophil carbamide and process for production of reagent
ES8801217A1 (es) Un procedimiento para la preparacion de un derivado de acido 5-imidazolcarboxilico
AU559148B2 (en) Foliage fertilizers
MD960212A (en) Acylfulvene analogs as antitumor remedy
ES476626A2 (es) Procedimiento para la preparacion de compuestos imidazoliniocuaternarios
DE3362504D1 (en) 1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use
ES8609271A1 (es) Procedimiento para preparar derivados de carbamoilimidazol fungicidas
GR3015561T3 (en) Herbicidal agent.
ES8707249A1 (es) Un procedimiento para preparar derivados de fosfina y oro
ES8801295A1 (es) Un procedimiento para preparar derivados de fosfina
ZA891434B (en) Azolylmethyloxiranes and fungicides containing these compounds
ES8500917A1 (es) Procedimiento para la obtencion de azolilmetilcicloalcanos
ES8704918A1 (es) Un procedimiento para la preparacion de nuevos derivados de esteres fosforicos.
GB8511891D0 (en) Alkenoic acids
GR1002355B (el) Μιγμα για την ρυθμιση της αναπτυξης των φυτων.
ES8302634A1 (es) Procedimiento de preparacion de derivados del acido metilen-2-succinamico
ATE18993T1 (de) Dibenzocycloheptenyliden-verbindungen zur verwendung bei der modulation der immunreaktion.
DE3561948D1 (en) Oximinophosphoric acid derivatives, process for their preparation and their use as pesticides
ES8704181A1 (es) Un procedimiento para preparar un compuesto de bis (difenilfosfino) alquil -bis-oro-i
DE3663664D1 (en) Compounds having antiplatelet aggregation activity, a process for the preparation thereof and pharmaceutical compositions containing them
ES8300709A1 (es) Un metodo para la preparacion de derivados de pirazolidinona
MD424G2 (ro) Derivaţi ai amidei