ES8606879A1 - Un procedimiento para la preparacion de derivados esteroida-les - Google Patents
Un procedimiento para la preparacion de derivados esteroida-lesInfo
- Publication number
- ES8606879A1 ES8606879A1 ES543646A ES543646A ES8606879A1 ES 8606879 A1 ES8606879 A1 ES 8606879A1 ES 543646 A ES543646 A ES 543646A ES 543646 A ES543646 A ES 543646A ES 8606879 A1 ES8606879 A1 ES 8606879A1
- Authority
- ES
- Spain
- Prior art keywords
- steroids
- alkyl
- alkylidene
- unsaturated
- double bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS ESTEROIDALES Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1, R2, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 2-4. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA NR2R3R4, EN LAS QUE X E Y PUEDEN SER VARIOS RADICALES, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, A LA TEMPERATURA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA INHIBICION DE LA RESORCION INTESTINAL DE COLESTEROL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH464483 | 1983-08-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8606879A1 true ES8606879A1 (es) | 1986-05-01 |
ES543646A0 ES543646A0 (es) | 1986-05-01 |
Family
ID=4279973
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES535391A Granted ES535391A0 (es) | 1983-08-25 | 1984-08-24 | Procedimiento para la preparacion de derivados esteroidales |
ES543646A Expired ES8606879A1 (es) | 1983-08-25 | 1985-05-30 | Un procedimiento para la preparacion de derivados esteroida-les |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES535391A Granted ES535391A0 (es) | 1983-08-25 | 1984-08-24 | Procedimiento para la preparacion de derivados esteroidales |
Country Status (21)
Country | Link |
---|---|
US (1) | US4680290A (es) |
EP (1) | EP0135762B1 (es) |
JP (1) | JPS6061595A (es) |
KR (1) | KR850001767A (es) |
AR (1) | AR240834A1 (es) |
AT (1) | ATE37883T1 (es) |
AU (1) | AU574706B2 (es) |
CA (1) | CA1252778A (es) |
DE (1) | DE3474552D1 (es) |
DK (1) | DK347584A (es) |
ES (2) | ES535391A0 (es) |
FI (1) | FI842830A (es) |
GR (1) | GR80196B (es) |
HU (1) | HU189929B (es) |
IL (1) | IL72725A (es) |
MC (1) | MC1618A1 (es) |
NO (1) | NO161679C (es) |
NZ (1) | NZ209275A (es) |
PH (1) | PH19849A (es) |
PT (1) | PT79130B (es) |
ZA (1) | ZA846430B (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1241947A (en) * | 1985-05-31 | 1988-09-13 | Pierre R. Proulx | Conjugated polyene sterol derivatives as membrane probes |
US4946834A (en) * | 1988-12-23 | 1990-08-07 | Smithkline Beecham Corporation | Phosphonic acid substituted steroids as steroid 5α-reductase inhibitors |
US5026882A (en) * | 1988-12-23 | 1991-06-25 | Smithkline Beecham Corporation | Phosphinic acid substituted steroids as inhibitors of steroid 5α-reductase |
US5215972A (en) * | 1989-11-22 | 1993-06-01 | Hoffmann-La Roche Inc. | Steroids |
CA2028759A1 (en) * | 1989-11-22 | 1991-05-23 | Jean-Marie Cassal | Steroids |
US5244887A (en) * | 1992-02-14 | 1993-09-14 | Straub Carl D | Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof |
CA2204902A1 (en) * | 1994-11-30 | 1996-06-06 | Fred I. Chasalow | Phosphocholine drug derivatives |
US6251939B1 (en) * | 1995-06-07 | 2001-06-26 | Promega Biosciences, Inc. | Carbamate-based cationic lipids |
AU705549B2 (en) * | 1995-06-07 | 1999-05-27 | Promega Biosciences, Inc. | Phosphonic acid-based cationic lipids |
JP2002514183A (ja) * | 1996-09-17 | 2002-05-14 | スーパージェン・インコーポレーテッド | リン脂質薬剤誘導体 |
US5830432A (en) * | 1997-03-31 | 1998-11-03 | Amur Pharmacuticals, Inc. | Phospholipid drug derivatives |
EP1079859B1 (en) | 1998-05-22 | 2010-07-14 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
CA2395447A1 (en) | 2000-01-28 | 2001-08-02 | Robert Joseph Sarama | Palatable arginine compounds and uses thereof for cardiovascular health |
US20030045473A1 (en) * | 2002-07-19 | 2003-03-06 | Sarama Robert Joseph | Compositions, kits, and methods for cardiovascular health |
SI1889198T1 (sl) | 2005-04-28 | 2015-02-27 | Proteus Digital Health, Inc. | Farma-informacijski sistem |
JP2009508494A (ja) | 2005-09-16 | 2009-03-05 | ラプトール ファーマシューティカル インコーポレイテッド | Crを含むタンパク質に対して特異的な受容体−結合タンパク質(rap)変異体を含む組成物およびその使用 |
JP2010511648A (ja) * | 2006-12-08 | 2010-04-15 | ジャド テクノロジーズ ゲーエムベーハー | 感染性疾患の治療及び予防のためのコレステリルアミン |
DK2398500T3 (da) | 2009-02-20 | 2019-05-13 | 2 Bbb Medicines B V | Glutathion-baseret lægemiddelafgivelsessystem |
ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
WO2023122075A1 (en) * | 2021-12-20 | 2023-06-29 | Ohio State Innovation Foundation | Compositions comprising sterol-amino-phosphate compounds and methods of making and use thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3248408A (en) * | 1963-07-22 | 1966-04-26 | Merck & Co Inc | Purification of steroid phosphates |
-
1984
- 1984-07-12 CA CA000458711A patent/CA1252778A/en not_active Expired
- 1984-07-13 DK DK347584A patent/DK347584A/da not_active Application Discontinuation
- 1984-07-13 FI FI842830A patent/FI842830A/fi not_active Application Discontinuation
- 1984-07-30 JP JP59157785A patent/JPS6061595A/ja active Pending
- 1984-08-09 AT AT84109517T patent/ATE37883T1/de not_active IP Right Cessation
- 1984-08-09 EP EP84109517A patent/EP0135762B1/de not_active Expired
- 1984-08-09 DE DE8484109517T patent/DE3474552D1/de not_active Expired
- 1984-08-10 US US06/639,543 patent/US4680290A/en not_active Expired - Fee Related
- 1984-08-17 ZA ZA846430A patent/ZA846430B/xx unknown
- 1984-08-17 NZ NZ209275A patent/NZ209275A/en unknown
- 1984-08-20 IL IL72725A patent/IL72725A/xx unknown
- 1984-08-21 AU AU32225/84A patent/AU574706B2/en not_active Ceased
- 1984-08-22 HU HU843153A patent/HU189929B/hu not_active IP Right Cessation
- 1984-08-22 AR AR297667A patent/AR240834A1/es active
- 1984-08-23 MC MC841722A patent/MC1618A1/xx unknown
- 1984-08-23 GR GR80196A patent/GR80196B/el unknown
- 1984-08-23 KR KR1019840005104A patent/KR850001767A/ko not_active Application Discontinuation
- 1984-08-24 PT PT79130A patent/PT79130B/pt unknown
- 1984-08-24 PH PH31145A patent/PH19849A/en unknown
- 1984-08-24 NO NO843406A patent/NO161679C/no unknown
- 1984-08-24 ES ES535391A patent/ES535391A0/es active Granted
-
1985
- 1985-05-30 ES ES543646A patent/ES8606879A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0135762A2 (de) | 1985-04-03 |
FI842830A0 (fi) | 1984-07-13 |
AR240834A1 (es) | 1991-02-28 |
AR240834A2 (es) | 1991-02-28 |
DE3474552D1 (en) | 1988-11-17 |
IL72725A (en) | 1988-07-31 |
ES8602844A1 (es) | 1985-12-01 |
HU189929B (en) | 1986-08-28 |
EP0135762B1 (de) | 1988-10-12 |
FI842830A (fi) | 1985-02-26 |
PT79130A (en) | 1984-09-01 |
AU574706B2 (en) | 1988-07-14 |
NZ209275A (en) | 1987-06-30 |
NO843406L (no) | 1985-02-26 |
CA1252778A (en) | 1989-04-18 |
US4680290A (en) | 1987-07-14 |
EP0135762A3 (en) | 1986-01-22 |
ATE37883T1 (de) | 1988-10-15 |
IL72725A0 (en) | 1984-11-30 |
GR80196B (en) | 1985-01-02 |
AU3222584A (en) | 1985-02-28 |
KR850001767A (ko) | 1985-04-01 |
PH19849A (en) | 1986-07-22 |
ES543646A0 (es) | 1986-05-01 |
DK347584A (da) | 1985-02-26 |
NO161679C (no) | 1989-09-13 |
ES535391A0 (es) | 1985-12-01 |
JPS6061595A (ja) | 1985-04-09 |
ZA846430B (en) | 1985-04-24 |
HUT34997A (en) | 1985-05-28 |
MC1618A1 (fr) | 1985-07-18 |
NO161679B (no) | 1989-06-05 |
PT79130B (en) | 1986-11-14 |
DK347584D0 (da) | 1984-07-13 |
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