ES8300779A1 - Procedimiento para preparar compuestos ciclohexamicos o cicloheptanicos sustituidos con n-(carboxilo esterificado o sul fonilo esterificado)-aminoalcoholico o-aminoalcohilideno. - Google Patents

Procedimiento para preparar compuestos ciclohexamicos o cicloheptanicos sustituidos con n-(carboxilo esterificado o sul fonilo esterificado)-aminoalcoholico o-aminoalcohilideno.

Info

Publication number
ES8300779A1
ES8300779A1 ES503085A ES503085A ES8300779A1 ES 8300779 A1 ES8300779 A1 ES 8300779A1 ES 503085 A ES503085 A ES 503085A ES 503085 A ES503085 A ES 503085A ES 8300779 A1 ES8300779 A1 ES 8300779A1
Authority
ES
Spain
Prior art keywords
group
formula
antihistamines
novel
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES503085A
Other languages
English (en)
Other versions
ES503085A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22578489&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8300779(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES503085A0 publication Critical patent/ES503085A0/es
Publication of ES8300779A1 publication Critical patent/ES8300779A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS CICLOHEXANICOS O CICLOHEPTANICOS DE FORMULA (I), EN LA QUE A ES UN GRUPO DE ATOMOS NECESARIOS PARA COMPLETAR UN HETEROCICLO AROMATICO O BENCENO FUSIONADOS; B ES UN GRUPO DE ATOMOS NECESARIO PARA COMPLETAR UN ANILLO DE PIRIDINA O BENCENO FUSIONADOS; Z ES UN ENLACE SENCILLO O UN GRUPO METILENO, ETILENO O VINILENO; R -R E Y PUEDEN SER VARIOS RADICALES; Y P VALE 1 O 2. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA TY'', EN LA QUE Y'' ES UN GRUPO REEMPLAZABLE; T ES UN GRUPO CAPAZ DE SER ELIMINADO CON Y'', Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, A LA TEMPERATURA DE REFLUJO. >ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIHISTAMINICA.
ES503085A 1980-06-19 1981-06-16 Procedimiento para preparar compuestos ciclohexamicos o cicloheptanicos sustituidos con n-(carboxilo esterificado o sul fonilo esterificado)-aminoalcoholico o-aminoalcohilideno. Expired ES8300779A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06160795 US4282233B1 (en) 1980-06-19 1980-06-19 Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines

Publications (2)

Publication Number Publication Date
ES503085A0 ES503085A0 (es) 1982-11-01
ES8300779A1 true ES8300779A1 (es) 1982-11-01

Family

ID=22578489

Family Applications (1)

Application Number Title Priority Date Filing Date
ES503085A Expired ES8300779A1 (es) 1980-06-19 1981-06-16 Procedimiento para preparar compuestos ciclohexamicos o cicloheptanicos sustituidos con n-(carboxilo esterificado o sul fonilo esterificado)-aminoalcoholico o-aminoalcohilideno.

Country Status (25)

Country Link
US (1) US4282233B1 (es)
EP (1) EP0042544B1 (es)
JP (1) JPS5735586A (es)
KR (1) KR850000744B1 (es)
AT (1) ATE9695T1 (es)
AU (1) AU543054B2 (es)
CA (1) CA1160230A (es)
CY (1) CY1405A (es)
DE (1) DE3166441D1 (es)
DK (1) DK169817B1 (es)
ES (1) ES8300779A1 (es)
FI (1) FI70213C (es)
HK (1) HK94387A (es)
HU (1) HU186774B (es)
IE (1) IE51303B1 (es)
IL (1) IL63122A (es)
KE (1) KE3758A (es)
LU (1) LU88359I2 (es)
MY (1) MY8700761A (es)
NL (1) NL930094I2 (es)
NZ (1) NZ197435A (es)
PH (1) PH19252A (es)
PT (1) PT73200B (es)
SG (1) SG70587G (es)
ZA (1) ZA814062B (es)

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DK263481A (da) 1981-12-20
HK94387A (en) 1987-12-18
AU543054B2 (en) 1985-03-28
DE3166441D1 (en) 1984-11-08
EP0042544A3 (en) 1982-04-07
CY1405A (en) 1988-04-22
FI70213B (fi) 1986-02-28
EP0042544B1 (en) 1984-10-03
FI70213C (fi) 1986-09-15
JPS5735586A (en) 1982-02-26
KR850000744B1 (ko) 1985-05-24
NZ197435A (en) 1984-03-30
PT73200A (en) 1981-07-01
FI811878L (fi) 1981-12-20
US4282233A (en) 1981-08-04
PT73200B (en) 1983-04-26
MY8700761A (en) 1987-12-31
SG70587G (en) 1988-02-19
IL63122A (en) 1985-06-30
NL930094I1 (nl) 1993-10-01
US4282233B1 (en) 2000-09-05
KE3758A (en) 1987-10-02
IE811328L (en) 1981-12-19
DK169817B1 (da) 1995-03-06
IE51303B1 (en) 1986-11-26
PH19252A (en) 1986-02-17
AU7186281A (en) 1981-12-24
ES503085A0 (es) 1982-11-01
LU88359I2 (fr) 1994-05-04
ATE9695T1 (de) 1984-10-15
HU186774B (en) 1985-09-30
CA1160230A (en) 1984-01-10
NL930094I2 (nl) 1994-12-01
KR830006218A (ko) 1983-09-20
ZA814062B (en) 1982-07-28
JPS6355513B2 (es) 1988-11-02
EP0042544A2 (en) 1981-12-30

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