ES548270A0 - Un metodo de inmunoensayo - Google Patents
Un metodo de inmunoensayoInfo
- Publication number
- ES548270A0 ES548270A0 ES548270A ES548270A ES548270A0 ES 548270 A0 ES548270 A0 ES 548270A0 ES 548270 A ES548270 A ES 548270A ES 548270 A ES548270 A ES 548270A ES 548270 A0 ES548270 A0 ES 548270A0
- Authority
- ES
- Spain
- Prior art keywords
- binding
- antibody reagent
- protein
- denaturation
- specific
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66581184A | 1984-10-29 | 1984-10-29 | |
US06/763,193 US4647654A (en) | 1984-10-29 | 1985-08-08 | Peptides useful in preparing hemoglobin A1c immunogens |
US06/779,731 US4727036A (en) | 1985-08-08 | 1985-09-27 | Antibodies for use in determining hemoglobin A1c |
US06/779,730 US4658022A (en) | 1985-08-08 | 1985-09-27 | Binding of antibody reagents to denatured protein analytes |
Publications (2)
Publication Number | Publication Date |
---|---|
ES548270A0 true ES548270A0 (es) | 1987-05-01 |
ES8705633A1 ES8705633A1 (es) | 1987-05-01 |
Family
ID=27505324
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548270A Expired ES8705633A1 (es) | 1984-10-29 | 1985-10-28 | Un metodo de inmunoensayo |
ES556865A Expired ES8800435A1 (es) | 1984-10-29 | 1986-07-01 | Un metodo de inmunoensayo. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES556865A Expired ES8800435A1 (es) | 1984-10-29 | 1986-07-01 | Un metodo de inmunoensayo. |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP0185870B2 (es) |
JP (2) | JPH0723891B2 (es) |
AT (2) | ATE80951T1 (es) |
AU (1) | AU594651B2 (es) |
CA (1) | CA1339952C (es) |
DE (2) | DE3587687T2 (es) |
DK (2) | DK167825B1 (es) |
ES (2) | ES8705633A1 (es) |
FI (1) | FI84107C (es) |
IE (1) | IE63731B1 (es) |
IL (1) | IL76827A (es) |
NZ (1) | NZ213959A (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5206144A (en) * | 1985-03-29 | 1993-04-27 | Novo Industri A/S | Determination of glycated (glycosylated) hemoglobin in blood |
DK145385D0 (da) * | 1985-03-29 | 1985-04-01 | Novo Industri As | Monoklonalt antistof til immunkemisk analyse |
US4797473A (en) * | 1986-06-25 | 1989-01-10 | Regents Of The University Of Minnesota | Monoclonal antibodies to unreduced, nonenzymatically-glycated proteins |
US5173422A (en) * | 1986-08-22 | 1992-12-22 | Miles Inc. | Monoclonal antibodies specific for human glycoalbumin |
US4822747A (en) * | 1986-12-09 | 1989-04-18 | Miles Inc. | Polyacrylamide gel particles having hapten moieties bound thereto as immunoassay reagent |
JPS63273472A (ja) * | 1987-04-30 | 1988-11-10 | Asahi Breweries Ltd | 新規抗体とそれを用いたヒトヘモグロビンの検出 |
US4970171A (en) * | 1987-11-09 | 1990-11-13 | Miles Inc. | Denaturant reagents for convenient determination of hemoglobin derivatives in blood |
US4847209A (en) * | 1987-11-09 | 1989-07-11 | Miles Inc. | Latex agglutination immunoassay in the presence of hemoglobin |
DE3806198A1 (de) * | 1988-02-04 | 1989-08-17 | Boehringer Mannheim Gmbh | Immunogen und seine verwendung zur gewinnung von antikoerpern gegen hba(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)c(pfeil abwaerts) |
IL94724A (en) * | 1989-07-13 | 1994-02-27 | Miles Inc | Decomposition of red blood cells and denaturation of hemoglobin by the use of lithium salts |
US5484735A (en) * | 1989-08-23 | 1996-01-16 | Northwestern University | Immunoassay of glycosylated proteins employing antibody directed to reductively glycosylated N-terminal amino acids |
DE4206932A1 (de) * | 1992-03-05 | 1993-09-09 | Boehringer Mannheim Gmbh | Immunologische methode zur bestimmung eines haemoglobinderivates |
JP2596322B2 (ja) * | 1992-06-10 | 1997-04-02 | 富士レビオ株式会社 | 総ヘモグロビンに対する糖化ヘモグロビンの割合の測定方法 |
AU661207B2 (en) * | 1992-11-17 | 1995-07-13 | Boehringer Mannheim Gmbh | Simultaneous determination of HbA1c and haemoglobin variants with a glycation analogus to HbA1c |
EP0711415B1 (de) * | 1993-07-28 | 1998-07-22 | Boehringer Mannheim Gmbh | Immunoassay zum nachweis von kollagen typ i oder kollagenfragmenten davon |
JP3269765B2 (ja) | 1995-12-14 | 2002-04-02 | 富士写真フイルム株式会社 | ヘモグロビン誘導体の免疫学的測定方法及びその方法に用いる処理試薬 |
US6573055B2 (en) | 1997-04-21 | 2003-06-03 | Glycozyme, Inc. | Determination of recombinant glycosylated proteins and peptides in biological fluids |
JPH10332693A (ja) * | 1997-05-29 | 1998-12-18 | Tokuyama Corp | 被検体の前処理方法 |
EP1015028A2 (en) * | 1997-09-19 | 2000-07-05 | Serex, Inc. | Methods to improve immunogenicity of antigens and specificity of antibodies |
AU9549798A (en) * | 1997-10-21 | 1999-05-10 | Cranfield University | Affinity ligands, their production and use |
JPH11258238A (ja) * | 1998-03-10 | 1999-09-24 | Tokuyama Corp | 免疫学的凝集測定用試薬キット |
CA2339360C (en) * | 1998-08-07 | 2008-07-29 | Sekisui Chemical Co., Ltd. | Method for determination of hemoglobins |
JP2002005936A (ja) * | 2000-06-26 | 2002-01-09 | Shino Test Corp | 酵素免疫測定法による測定試薬及び測定方法 |
WO2002006310A1 (fr) * | 2000-07-14 | 2002-01-24 | Matsushita Electric Industrial Co., Ltd. | Fructose peptidique et complexe de ce dernier associe a une proteine de liaison |
JP4318458B2 (ja) * | 2001-04-26 | 2009-08-26 | ダコ デンマーク アクティーゼルスカブ | pan特異的モノクローナル抗体 |
EP1816460B1 (en) | 2006-02-03 | 2009-07-22 | MTM Laboratories AG | Method of performing a denaturing immunassay |
JP5156738B2 (ja) * | 2006-06-06 | 2013-03-06 | エフ.ホフマン−ラ ロシュ アーゲー | 全血試料の特異的溶血 |
JP5183635B2 (ja) * | 2006-10-18 | 2013-04-17 | ビオメリュー | Pvl産生黄色ブドウ球菌のインビトロにおける診断方法 |
CA2682005C (en) * | 2007-06-06 | 2011-10-25 | F. Hoffmann-La Roche Ag | Detection of an analyte in a sample of hemolyzed whole blood |
CN102246036B (zh) | 2008-12-11 | 2016-01-20 | 积水医疗株式会社 | 含有糖化血红蛋白的试样的前处理方法 |
EP2357199A4 (en) | 2008-12-11 | 2013-02-20 | Sekisui Medical Co Ltd | ANTIBODIES TO N-TERMINUS OF THE β-CHAIN OF HEMOGLOBIN |
WO2017096373A1 (en) * | 2015-12-04 | 2017-06-08 | Polymer Technology Systems, Inc. | Systems and methods for interference correction from hemoglobin variants |
JP6811581B2 (ja) * | 2016-10-25 | 2021-01-13 | 福井県 | 人血検査方法及び人血検査用キット |
SG11202103027UA (en) | 2018-09-28 | 2021-04-29 | Sekisui Medical Co Ltd | Glycated hemoglobin (%) assay method |
US20200284807A1 (en) * | 2019-03-05 | 2020-09-10 | Victor Manneh | Saturation binding ratiometric assay |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4247533A (en) * | 1978-05-01 | 1981-01-27 | The Rockefeller University | Hemoglobin A1c radioimmunoassay |
GB1580318A (en) * | 1978-05-06 | 1980-12-03 | Univ Rockefeller | Antibodies active against human hemoglobin a1c |
JPS5610254A (en) * | 1979-07-07 | 1981-02-02 | Wako Pure Chem Ind Ltd | New rheumatism factor measuring reagent |
US4478744A (en) * | 1982-01-25 | 1984-10-23 | Sherwood Medical Company | Method of obtaining antibodies |
JPS58205854A (ja) * | 1982-05-25 | 1983-11-30 | Mihama Hisaharu | 潜血反応検査用の固定化抗体 |
US4629692A (en) * | 1982-12-06 | 1986-12-16 | Miles Laboratories, Inc. | Immunoassay for nonenzymatically glucosylated proteins and protein fragments an index of glycemia |
DE3439610A1 (de) * | 1984-10-30 | 1986-04-30 | Boehringer Mannheim Gmbh, 6800 Mannheim | Immunogene, verfahren zu deren herstellung sowie damit gewonnene antikoerper gegen glykosiliertes haemoglobin |
DK145385D0 (da) * | 1985-03-29 | 1985-04-01 | Novo Industri As | Monoklonalt antistof til immunkemisk analyse |
-
1985
- 1985-10-08 CA CA000492444A patent/CA1339952C/en not_active Expired - Lifetime
- 1985-10-17 DE DE89100369T patent/DE3587687T2/de not_active Expired - Lifetime
- 1985-10-17 EP EP85113157A patent/EP0185870B2/en not_active Expired - Lifetime
- 1985-10-17 AT AT85113157T patent/ATE80951T1/de not_active IP Right Cessation
- 1985-10-17 DE DE3586679T patent/DE3586679T3/de not_active Expired - Lifetime
- 1985-10-17 EP EP89100369A patent/EP0316306B1/en not_active Expired - Lifetime
- 1985-10-25 FI FI854187A patent/FI84107C/fi not_active IP Right Cessation
- 1985-10-25 IE IE265585A patent/IE63731B1/en not_active IP Right Cessation
- 1985-10-25 NZ NZ213959A patent/NZ213959A/xx unknown
- 1985-10-25 IL IL76827A patent/IL76827A/xx not_active IP Right Cessation
- 1985-10-28 ES ES548270A patent/ES8705633A1/es not_active Expired
- 1985-10-28 DK DK494085A patent/DK167825B1/da not_active IP Right Cessation
- 1985-10-29 JP JP60240703A patent/JPH0723891B2/ja not_active Expired - Lifetime
- 1985-10-31 AU AU49260/85A patent/AU594651B2/en not_active Expired
-
1986
- 1986-07-01 ES ES556865A patent/ES8800435A1/es not_active Expired
-
1989
- 1989-01-11 AT AT89100369T patent/ATE98776T1/de not_active IP Right Cessation
-
1991
- 1991-07-04 DK DK199101307A patent/DK165327C/da not_active IP Right Cessation
-
1994
- 1994-01-19 JP JP6018988A patent/JP2858534B2/ja not_active Expired - Lifetime
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20070120 |