ES486991A1 - Un procedimiento para la preparacion de un derivado de car- boestirilo - Google Patents

Un procedimiento para la preparacion de un derivado de car- boestirilo

Info

Publication number
ES486991A1
ES486991A1 ES486991A ES486991A ES486991A1 ES 486991 A1 ES486991 A1 ES 486991A1 ES 486991 A ES486991 A ES 486991A ES 486991 A ES486991 A ES 486991A ES 486991 A1 ES486991 A1 ES 486991A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
hydrogen atom
alkyl
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES486991A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of ES486991A1 publication Critical patent/ES486991A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

En lo que se refiere a las actividades de control nervioso central, los compuestos de la presente invención se caracterizan porque presentan fuertes actividades de control sobre la actitud de lucha de ratones que han permanecido aislados durante largos periodos de tiempo. Así. En comparación con el Diazepam, que es un compuesto con una reconocida elevada actividad de este tipo, los compuestos de la presente invención tiene un importante efecto de control sobre la actitud de lucha de ratones. Por tanto, los compuestos presentes son bastantes útiles particularmente como sedantes, fármacos anti-ansiedad, y fármacos anti-psicosis maniaco depresiva. Además los compuestos de la presente invención aumentan fuertemente la anestesia y el sueño cuando se utilizan en combinación con anestésicos e hipnóticos.
ES486991A 1978-03-30 1979-12-17 Un procedimiento para la preparacion de un derivado de car- boestirilo Expired ES486991A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3778378A JPS54130587A (en) 1978-03-30 1978-03-30 Carbostyryl derivative

Publications (1)

Publication Number Publication Date
ES486991A1 true ES486991A1 (es) 1980-10-01

Family

ID=12507080

Family Applications (4)

Application Number Title Priority Date Filing Date
ES479134A Expired ES479134A1 (es) 1978-03-30 1979-03-30 Un procedimiento para la preparacion de un derivado de car- boestirilo.
ES486992A Expired ES486992A1 (es) 1978-03-30 1979-12-17 Un procedimiento para la preparacion de un derivado de car- boestirilo
ES486991A Expired ES486991A1 (es) 1978-03-30 1979-12-17 Un procedimiento para la preparacion de un derivado de car- boestirilo
ES486990A Expired ES486990A1 (es) 1978-03-30 1979-12-17 Un procedimiento para la preparacion de un derivado de car- boestirilo

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES479134A Expired ES479134A1 (es) 1978-03-30 1979-03-30 Un procedimiento para la preparacion de un derivado de car- boestirilo.
ES486992A Expired ES486992A1 (es) 1978-03-30 1979-12-17 Un procedimiento para la preparacion de un derivado de car- boestirilo

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES486990A Expired ES486990A1 (es) 1978-03-30 1979-12-17 Un procedimiento para la preparacion de un derivado de car- boestirilo

Country Status (21)

Country Link
US (2) US4734416A (es)
JP (1) JPS54130587A (es)
AT (1) AT376432B (es)
AU (1) AU515531B2 (es)
BE (1) BE875174A (es)
CA (1) CA1117110A (es)
CH (2) CH641455A5 (es)
DE (2) DE2953723C2 (es)
DK (1) DK158225C (es)
ES (4) ES479134A1 (es)
FI (1) FI70704C (es)
FR (1) FR2421174A1 (es)
GB (1) GB2017701B (es)
IT (1) IT1119284B (es)
MX (1) MX5862E (es)
NL (1) NL183189C (es)
NO (1) NO151321C (es)
PT (1) PT69422A (es)
SE (1) SE434945B (es)
SU (2) SU1140687A3 (es)
ZA (1) ZA791516B (es)

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US4824840A (en) 1989-04-25
DE2912105C2 (de) 1985-08-29
FI70704B (fi) 1986-06-26
SU1232144A3 (ru) 1986-05-15
CH641350A5 (de) 1984-02-29
SE7902794L (sv) 1979-10-01
NL183189C (nl) 1988-08-16
NL7902514A (nl) 1979-10-02
IT7967674A0 (it) 1979-03-30
MX5862E (es) 1984-08-13
NO151321B (no) 1984-12-10
AU515531B2 (en) 1981-04-09
DE2912105A1 (de) 1979-10-11
US4734416A (en) 1988-03-29
ES486990A1 (es) 1980-10-01
FI70704C (fi) 1986-10-06
FI791034A (fi) 1979-10-01
ES486992A1 (es) 1980-10-01
DK128679A (da) 1979-10-26
ZA791516B (en) 1980-04-30
CA1117110A (en) 1982-01-26
AU4548079A (en) 1979-10-04
BE875174A (fr) 1979-10-01
DK158225B (da) 1990-04-16
SE434945B (sv) 1984-08-27
IT1119284B (it) 1986-03-10
ATA235179A (de) 1984-04-15
ES479134A1 (es) 1980-06-16
GB2017701B (en) 1983-03-16
FR2421174A1 (fr) 1979-10-26
DK158225C (da) 1990-09-17
JPS6223750B2 (es) 1987-05-25
JPS54130587A (en) 1979-10-09
SU1140687A3 (ru) 1985-02-15
FR2421174B1 (es) 1982-11-19
DE2953723C2 (de) 1989-01-12
CH641455A5 (de) 1984-02-29
NO151321C (no) 1985-03-20
AT376432B (de) 1984-11-26
GB2017701A (en) 1979-10-10
NO791049L (no) 1979-10-02
PT69422A (en) 1979-04-01

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