ES2891574T3 - Células madre mesenquimales para su uso en el mejoramiento de la función pulmonar - Google Patents
Células madre mesenquimales para su uso en el mejoramiento de la función pulmonar Download PDFInfo
- Publication number
- ES2891574T3 ES2891574T3 ES19204349T ES19204349T ES2891574T3 ES 2891574 T3 ES2891574 T3 ES 2891574T3 ES 19204349 T ES19204349 T ES 19204349T ES 19204349 T ES19204349 T ES 19204349T ES 2891574 T3 ES2891574 T3 ES 2891574T3
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- cells
- mesenchymal stem
- stem cells
- mscs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cardiology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/726,676 US20080095749A1 (en) | 2004-03-22 | 2007-03-22 | Mesenchymal stem cells and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2891574T3 true ES2891574T3 (es) | 2022-01-28 |
Family
ID=39735516
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES19204349T Active ES2891574T3 (es) | 2007-03-22 | 2008-03-21 | Células madre mesenquimales para su uso en el mejoramiento de la función pulmonar |
| ES21195085T Active ES2988291T3 (es) | 2007-03-22 | 2008-03-21 | Células madre mesenquimales para uso en el tratamiento de la fibrosis pulmonar idiopática |
| ES16171424T Active ES2765650T3 (es) | 2007-03-22 | 2008-03-21 | Células madre mesenquimales para su uso en el mejoramiento de la función pulmonar |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES21195085T Active ES2988291T3 (es) | 2007-03-22 | 2008-03-21 | Células madre mesenquimales para uso en el tratamiento de la fibrosis pulmonar idiopática |
| ES16171424T Active ES2765650T3 (es) | 2007-03-22 | 2008-03-21 | Células madre mesenquimales para su uso en el mejoramiento de la función pulmonar |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20080095749A1 (enExample) |
| EP (6) | EP3095450B1 (enExample) |
| JP (2) | JP2010522212A (enExample) |
| KR (7) | KR20090122415A (enExample) |
| CN (1) | CN101626772A (enExample) |
| BR (1) | BRPI0802241A2 (enExample) |
| CA (2) | CA3134185A1 (enExample) |
| DK (1) | DK2123747T3 (enExample) |
| ES (3) | ES2891574T3 (enExample) |
| WO (1) | WO2008116157A2 (enExample) |
Families Citing this family (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2564679C (en) | 2004-03-22 | 2015-06-23 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
| WO2005097147A1 (en) * | 2004-03-30 | 2005-10-20 | Boston Scientific Limited (Incorporated In Ireland) | Restenosis therapy using mesenchymal stem cells |
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| SG10202001007TA (en) | 2005-09-23 | 2020-03-30 | Tigenix Sau | Cell populations having immunoregulatory activity, method for isolation and uses |
| EP1957633B1 (en) * | 2005-10-13 | 2013-12-18 | Anthrogenesis Corporation | Immunomodulation using placental stem cells |
| KR20180105266A (ko) | 2005-12-29 | 2018-09-27 | 안트로제네시스 코포레이션 | 태반 줄기 세포 집단 |
| CN101370930A (zh) | 2006-01-13 | 2009-02-18 | 奥西里斯治疗公司 | 表达TNF-α受体的间充质干细胞 |
| CN103356710A (zh) | 2007-02-12 | 2013-10-23 | 人类起源公司 | 利用胎盘干细胞治疗炎性疾病 |
| JP5541845B2 (ja) * | 2008-03-28 | 2014-07-09 | Jcrファーマ株式会社 | アトピー性皮膚炎治療剤 |
| WO2009134429A2 (en) * | 2008-05-02 | 2009-11-05 | Massachusetts Institute Of Technology | Methods and compositions for modulating immunological tolerance |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| NZ591292A (en) | 2008-08-20 | 2012-10-26 | Anthrogenesis Corp | Improved cell composition and methods of making the same |
| SI2331109T1 (sl) | 2008-08-22 | 2013-10-30 | Anthrogenesis Corporation | Postopki in sestavki za zdravljenje okvar kosti s populacijami placentarnih celic |
| US20110177015A1 (en) * | 2008-10-05 | 2011-07-21 | Hymie Friedlander | Skin and hair care using extract from conditioned medium cultured by mesenchymal stem cells and other regenerative cells |
| WO2010059828A1 (en) | 2008-11-19 | 2010-05-27 | Anthrogenesis Corporation | Amnion derived adherent cells |
| SG10201404280XA (en) * | 2009-07-21 | 2014-10-30 | Abt Holding Co | Use of stem cells to reduce leukocyte extravasation |
| WO2011070974A1 (ja) * | 2009-12-07 | 2011-06-16 | 国立大学法人名古屋大学 | 脂肪組織由来間葉系幹細胞を含有する、前立腺癌治療用細胞製剤 |
| WO2011072399A1 (en) * | 2009-12-18 | 2011-06-23 | The Governing Council Of The University Of Toronto | Injectable polymer composition for use as a cell delivery vehicle |
| KR20130092394A (ko) | 2010-04-08 | 2013-08-20 | 안트로제네시스 코포레이션 | 태반 줄기 세포를 사용한 사르코이드증의 치료 |
| KR101677293B1 (ko) * | 2010-04-16 | 2016-11-17 | 서울대학교병원 | 줄기세포의 활성을 증가시키는 방법 및 상기 방법에 의해 제조된 고활성 줄기 세포 |
| DK2568991T6 (en) | 2010-05-12 | 2019-03-18 | Abt Holding Co | MODULATION OF SPLENOCYTES IN CELL THERAPY |
| WO2012048093A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Enhanced msc preparations |
| CN101991880A (zh) * | 2010-11-08 | 2011-03-30 | 中国人民解放军军事医学科学院基础医学研究所 | 由复合msc的plga/tcp和msc组成的制剂及其应用 |
| CN101991878A (zh) * | 2010-11-08 | 2011-03-30 | 中国人民解放军军事医学科学院基础医学研究所 | 由复合msc的plga和msc组成的制剂及其应用 |
| US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
| KR102063069B1 (ko) * | 2011-03-11 | 2020-01-08 | 칠드런'즈 메디컬 센터 코포레이션 | 중간엽 줄기 세포 엑소솜에 관련된 방법 및 조성물 |
| DK2714059T3 (en) | 2011-06-01 | 2019-01-21 | Celularity Inc | TREATMENT OF PAIN WHEN USING PLACENT STAM CELLS |
| PL2785359T3 (pl) | 2011-11-30 | 2018-12-31 | Astellas Institute For Regenerative Medicine | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| CN103191154B (zh) * | 2012-01-06 | 2015-09-09 | 上海交通大学医学院 | 充质干细胞及其提取方法在制备银屑病的药物中的应用 |
| US20150110751A1 (en) * | 2012-05-16 | 2015-04-23 | Kennedy Krieger Institute, Inc. | Stem cells as an individualized maternal therapy for prevention of prematurity |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| CA2893951C (en) * | 2012-12-12 | 2022-05-03 | Mesoblast, Inc. | Methods of treating or preventing respiratory conditions |
| SG11201504340YA (en) * | 2012-12-12 | 2015-07-30 | Mesoblast Inc | Treatment of diseases of endothelial dysfunction and inflammation |
| EP3446708A1 (en) * | 2012-12-24 | 2019-02-27 | Cell Ideas Pty Ltd. | Vaccines for the treatment of cancer and compositions for enhancing vaccine efficacy |
| JP6571537B2 (ja) * | 2013-03-13 | 2019-09-04 | ザ ユニバーシティー オブ クイーンズランド | 療法および予防のための細胞を単離する方法 |
| KR102161726B1 (ko) | 2013-04-12 | 2020-10-06 | 사베리오 라프란체스카 | 이식용 장기의 개선 |
| US20160120910A1 (en) * | 2013-06-25 | 2016-05-05 | Tigenix S.A.U. | Cell populations having immunoregulatory activity, methods for the preparation and uses thereof |
| KR20160073382A (ko) * | 2013-10-04 | 2016-06-24 | 셀 아이디어스 피티와이 엘티디 | 세포 치료를 위한 바이오마커들 |
| JP6210049B2 (ja) | 2014-11-04 | 2017-10-11 | トヨタ自動車株式会社 | 車両 |
| PL3242933T3 (pl) * | 2015-01-08 | 2019-08-30 | Apceth Gmbh & Co. Kg | Zmodyfikowane genetycznie mezenchymalne komórki macierzyste wykazujące ekspresję alfa-1 antytrypsyny (aat) |
| WO2016146819A1 (en) * | 2015-03-18 | 2016-09-22 | Apceth Gmbh & Co. Kg | Hypoxia-induced expression of therapeutic proteins in mesenchymal stem cells |
| JP6811724B2 (ja) * | 2015-04-24 | 2021-01-13 | ティジェニクス エス.エー.ユー. | 細胞療法に対する臨床応答を決定するためのバイオマーカー |
| HK1258470A1 (zh) | 2015-10-07 | 2019-11-15 | 善威生物私人有限公司 | 血液制备和图谱分析 |
| AU2016374643B2 (en) * | 2015-12-22 | 2023-12-14 | Sangui Bio Pty. Ltd | Therapeutic methods using erythrocytes |
| GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| CN105769911A (zh) * | 2016-03-23 | 2016-07-20 | 中国人民解放军第二军医大学 | 间充质干细胞诱导斑秃处毛发再生的方法及应用 |
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| KR101970642B1 (ko) * | 2016-04-06 | 2019-05-17 | 주식회사 제이제이메이딘 | 줄기세포 배양용 배지조성물 및 그를 이용한 줄기세포 배양방법 |
| CN109104869B (zh) * | 2016-04-27 | 2022-07-01 | 日本乐敦制药株式会社 | 表达细胞表面标记物的间充质干细胞、包含该间充质干细胞的药物组合物及其制备方法 |
| KR101830290B1 (ko) | 2016-08-05 | 2018-02-21 | 한양대학교 에리카산학협력단 | 지방 유래 줄기세포로부터 추출된 엑소좀을 유효성분으로 포함하는 폐 섬유증 예방 또는 치료용 조성물 |
| EP3543331A4 (en) | 2016-11-15 | 2020-07-01 | Kaneka Corporation | CELL POPULATION CONTAINING MESENCHYMAL STEM CELLS DERIVED FROM F RATE APPENDICES, METHOD FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION |
| CN106492194A (zh) * | 2016-11-30 | 2017-03-15 | 广州赛莱拉干细胞科技股份有限公司 | 一种干细胞外泌体制剂及其制备方法和应用 |
| JP2020502545A (ja) | 2016-12-20 | 2020-01-23 | サングイ バイオ ピーティーワイ. エルティーディー | プロテアーゼインヒビターを用いる血液プロファイリング |
| JP7082372B2 (ja) * | 2017-02-15 | 2022-06-08 | ロート製薬株式会社 | 肺線維症治療剤、ptprr発現促進剤及び肺線維症治療用キット |
| CN118662615A (zh) | 2017-03-15 | 2024-09-20 | 浩康生物系统公司 | 用于造血干细胞移植的组合物和方法 |
| WO2019102268A1 (en) | 2017-11-22 | 2019-05-31 | Mesoblast International Sarl | Cellular compositions and methods of treatment i |
| JP7454379B2 (ja) | 2017-12-28 | 2024-03-22 | 株式会社カネカ | 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物 |
| CN108451981B (zh) * | 2018-04-21 | 2019-07-23 | 江西汉氏联合干细胞科技有限公司 | 使用皮肤间充质干细胞治疗系统性硬化症 |
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| CN110772537A (zh) * | 2019-11-07 | 2020-02-11 | 深圳科康干细胞技术有限公司 | 脐带血间充质干细胞组合物在治疗慢性阻塞性肺疾病中的应用 |
| WO2021176001A1 (en) * | 2020-03-05 | 2021-09-10 | Mesoblast International Sàrl | Method for treating inflammatory lung diseases using mesenchymal lineage precursor or stem cells |
| JP2023520233A (ja) * | 2020-04-03 | 2023-05-16 | メゾブラスト・インターナショナル・エスアーエールエル | 間葉系統前駆細胞又は幹細胞を使用する過炎症の治療方法 |
| US20210315937A1 (en) * | 2020-04-08 | 2021-10-14 | University Of South Florida | Methods of treating inflammation |
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| EP3909594A1 (en) * | 2020-05-14 | 2021-11-17 | Bernat Soria Escoms | Mesenchymal stromal cells for the treatment of covid-19 and other inflammatory, autoimmune and degenerative diseases |
| CN111568930A (zh) * | 2020-05-23 | 2020-08-25 | 湖南源品细胞生物科技有限公司 | 一种msc用于调节nk细胞数量的应用 |
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| CN112076217A (zh) * | 2020-10-26 | 2020-12-15 | 重庆医科大学附属第一医院 | 一种间充质干细胞来源的抗炎症氧化脂质组合物的制备方法 |
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