|
US2519863A
(en)
|
1949-05-14 |
1950-08-22 |
Eastman Kodak Co |
Conversion of beta-, gamma-, and delta-tocopherol to alpha-tocopherol by aminoalkylation and reduction
|
|
EP0159018A3
(en)
*
|
1984-04-17 |
1986-10-01 |
HENKEL CORPORATION (a Delaware corp.) |
Production of d-alpha-tocopherol from natural plant sources
|
|
US4977282A
(en)
|
1984-04-17 |
1990-12-11 |
Henkel Corporation |
Production of d-alpha-tocopherol from natural plant sources
|
|
US4603142A
(en)
|
1984-06-01 |
1986-07-29 |
Wisconsin Alumni Research Foundation |
Cholesterol lowering method of use
|
|
JPS636186A
(ja)
|
1986-06-23 |
1988-01-12 |
タツタ電線株式会社 |
点滴監視装置
|
|
JPH0788376B2
(ja)
|
1986-09-02 |
1995-09-27 |
エーザイ株式会社 |
光学活性α−トコトリエノ−ルの製造方法
|
|
JP2685785B2
(ja)
|
1988-03-11 |
1997-12-03 |
エーザイ株式会社 |
光学活性α−トコトリエノールの製造方法
|
|
JPH029875A
(ja)
|
1988-03-16 |
1990-01-12 |
Bio Ind Kyokai |
トコフェロール及びトコトリエノールの製造方法
|
|
US5157132A
(en)
|
1990-05-18 |
1992-10-20 |
Carotech Associates |
Integrated process for recovery of carotenoids and tocotrienols from oil
|
|
US5591772A
(en)
|
1991-11-22 |
1997-01-07 |
Lipogenics, Inc. |
Tocotrienols and tocotrienol-like compounds and methods for their use
|
|
DE59605564D1
(de)
*
|
1995-03-28 |
2000-08-17 |
Hoffmann La Roche |
Aminomethylierung von Tocopherolen
|
|
US5660691A
(en)
|
1995-11-13 |
1997-08-26 |
Eastman Chemical Company |
Process for the production of tocotrienol/tocopherol blend concentrates
|
|
US6232060B1
(en)
|
1996-01-19 |
2001-05-15 |
Galileo Laboratories, Inc. |
Assay system for anti-stress agents
|
|
US5801159A
(en)
|
1996-02-23 |
1998-09-01 |
Galileo Laboratories, Inc. |
Method and composition for inhibiting cellular irreversible changes due to stress
|
|
US5932748A
(en)
|
1997-06-06 |
1999-08-03 |
Roche Vitamins Inc. |
Process for permethylating non-α-tocopherols to produce α-tocopherol
|
|
WO1999021819A1
(en)
*
|
1997-10-29 |
1999-05-06 |
Flexsys America L.P. |
Preparation of quinonediimines from phenylenediamines using hydrogen peroxide and a catalyst
|
|
US6159347A
(en)
|
1998-01-29 |
2000-12-12 |
Eastman Chemical Company |
Methods for separating a tocol from a tocol-containing mixture
|
|
JP3258003B2
(ja)
|
1998-11-06 |
2002-02-18 |
富士化学工業株式会社 |
トコトリエノール類含有粉末、その製造方法およびそれを圧縮成型してなる錠剤
|
|
US6395915B1
(en)
|
1999-09-10 |
2002-05-28 |
Technikrom, Inc. |
Method for producing purified tocotrienols and tocopherols using liquid chromatography
|
|
MY127451A
(en)
|
1999-11-04 |
2006-12-29 |
Malaysian Palm Oil Board |
A method of chromatographic isolation for vitamin e isomers
|
|
DE10034233A1
(de)
*
|
2000-07-14 |
2002-01-24 |
Basf Ag |
Tocotrienolchinon-Cyclisierungsprodukte
|
|
US7034054B2
(en)
|
2000-12-15 |
2006-04-25 |
Galileo Pharmaceuticals, Inc. |
Methods for the prevention and treatment of cerebral ischemia using non-alpha tocopherols
|
|
US6838104B2
(en)
|
2000-12-20 |
2005-01-04 |
Archer Daniels Midland Company |
Process for the production of tocotrienols
|
|
US6608196B2
(en)
|
2001-05-03 |
2003-08-19 |
Galileo Pharmaceuticals, Inc. |
Process for solid supported synthesis of pyruvate-derived compounds
|
|
JP4842455B2
(ja)
|
2001-06-13 |
2011-12-21 |
コマツNtc株式会社 |
半導体単結晶引上げ装置及びそのライン構成
|
|
JP2003171376A
(ja)
|
2001-09-27 |
2003-06-20 |
Lion Corp |
トコフェロール類及びトコトリエノール類濃縮物、その製造方法
|
|
US6667330B2
(en)
|
2002-01-31 |
2003-12-23 |
Galileo Pharmaceuticals, Inc. |
Furanone derivatives
|
|
US6653346B1
(en)
|
2002-02-07 |
2003-11-25 |
Galileo Pharmaceuticals, Inc. |
Cytoprotective benzofuran derivatives
|
|
US6590113B1
(en)
|
2002-03-26 |
2003-07-08 |
Ronald T. Sleeter |
Process for treating oils containing antioxidant compounds
|
|
EP1558922B1
(en)
|
2002-10-30 |
2013-02-27 |
Ampere Life Sciences, Inc. |
Identifying therapeutic compounds based on their physical-chemical properties
|
|
MY130618A
(en)
*
|
2002-11-27 |
2007-07-31 |
Malaysian Palm Oil Board |
A method of extracting and isolating minor components from vegetable oil
|
|
US20050065099A1
(en)
|
2003-09-19 |
2005-03-24 |
Gail Walkinshaw |
Treatment of mitochondrial diseases
|
|
WO2005035491A2
(en)
|
2003-10-10 |
2005-04-21 |
Yasoo Health, Inc. |
PROCESS FOR SYNTHESIZING d-TOCOTRIENOLS FROM 2- VINYLCHROMANE COMPOUND
|
|
MY173044A
(en)
|
2003-11-19 |
2019-12-20 |
Carotech Bhd |
Recovery of phytonutriens from oils
|
|
US7393662B2
(en)
|
2004-09-03 |
2008-07-01 |
Centocor, Inc. |
Human EPO mimetic hinge core mimetibodies, compositions, methods and uses
|
|
WO2006130775A2
(en)
*
|
2005-06-01 |
2006-12-07 |
Edison Pharmaceuticals, Inc. |
Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomakers
|
|
DK1933821T3
(da)
|
2005-09-15 |
2020-10-26 |
Ptc Therapeutics Inc |
Halevarianter af redox-aktive terapeutika til behandling af mitokondriesygdomme og andre tilstande og modulation af energibiomarkører
|
|
EA019675B1
(ru)
|
2006-02-22 |
2014-05-30 |
Эдисон Фармасьютикалз, Инк. |
Редокс-активные терапевтические средства для лечения митохондриальных заболеваний и модуляции биомаркера коэнзима q
|
|
WO2007105297A1
(ja)
*
|
2006-03-13 |
2007-09-20 |
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo |
メチン系色素とその用途
|
|
AU2008205263A1
(en)
|
2007-01-10 |
2008-07-17 |
Edison Pharmaceuticals, Inc. |
Treatment of respiratory chain disorders using compounds having erythropoietin or thrombopoietin activity
|
|
MY162051A
(en)
|
2007-05-24 |
2017-05-31 |
Loders Croklaan Bv |
Process for producing compositions comprising tocopherols and tocotrienols
|
|
SI2220030T1
(sl)
|
2007-11-06 |
2016-04-29 |
Edison Pharmaceuticals, Inc. |
Derivati 4-(p-kuinonil)-2-hidroksibutanamida za zdravljenje mitohondrijskih bolezni
|
|
MX2010007443A
(es)
|
2008-01-07 |
2010-08-16 |
Centocor Ortho Biotech Inc |
Metodo para tratar anemias de respuesta baja a eritropoyetina.
|
|
WO2009089224A1
(en)
|
2008-01-08 |
2009-07-16 |
Edison Pharmaceuticals, Inc. |
(HET) ARYL-p-QUINONE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES
|
|
US8716527B2
(en)
|
2008-03-05 |
2014-05-06 |
Edison Pharmaceuticals, Inc. |
2-substituted-p-quinone derivatives for treatment of oxidative stress diseases
|
|
US20110046156A1
(en)
*
|
2008-03-05 |
2011-02-24 |
Miller Guy M |
Treatment of hearing and balance impairments with redox-active therapeutics
|
|
CA2723621A1
(en)
|
2008-05-15 |
2009-11-19 |
Edison Pharmaceuticals, Inc |
Treatment of hearing and balance impairments using compounds having erythropoietin activity
|
|
CA2724841A1
(en)
|
2008-05-22 |
2009-11-26 |
Edison Pharmaceuticals, Inc. |
Treatment of mitochondrial diseases with an erythropoietin mimetic
|
|
US8716486B2
(en)
|
2008-06-25 |
2014-05-06 |
Edison Pharmaceuticals, Inc. |
2-heterocyclylaminoalkyl-(p-quinone) derivatives for treatment of oxidative stress diseases
|
|
WO2010005989A1
(en)
|
2008-07-09 |
2010-01-14 |
Edison Pharmaceuticals, Inc. |
Dermatological compositions with anti-aging and skin even-toning properties
|
|
WO2010014758A1
(en)
|
2008-07-30 |
2010-02-04 |
Edison Pharmaceuticals, Inc. |
Use of hydrogenated pyrido[4,3-b] indoles for the treatment of oxidative stress
|
|
US20100029784A1
(en)
|
2008-07-30 |
2010-02-04 |
Hinman Andrew W |
Naphthoquinone compositions with anti-aging, anti-inflammatory and skin even-toning properties
|
|
BRPI0918139B1
(pt)
*
|
2008-09-10 |
2024-04-30 |
Ptc Therapeutics, Inc |
Composição, alimento medicinal ou funcional, suplemento alimentar ou dietético para tratamento de distúrbios de desenvolvimento pervasivos com terapêuticos redox-ativos
|
|
CA2740773A1
(en)
|
2008-10-14 |
2010-04-22 |
Edison Pharmaceuticals, Inc. |
Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells
|
|
CA2974482C
(en)
|
2008-10-28 |
2019-10-29 |
Bioelectron Technology Corporation |
High purity alpha tocotrienol quinone and processes for preparing same
|
|
BRPI1015006A2
(pt)
|
2009-04-28 |
2019-09-24 |
Ampere Life Sciences Inc |
uso tópico, periocular, ou intraocular de tocotrienóis para o tratamento de doenças oftálmicas
|
|
EP2424495B1
(en)
|
2009-04-28 |
2018-01-17 |
Bioelectron Technology Corporation |
Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones
|
|
EA201101576A1
(ru)
|
2009-04-28 |
2012-04-30 |
Эдисон Фармасьютикалз, Инк. |
Лекарственная форма токотриенол хинонов для лечения офтальмических (глазных) заболеваний
|
|
EP2445519A4
(en)
|
2009-06-25 |
2012-12-26 |
Ampere Life Sciences Inc |
TREATMENT OF PERVASIVE DEVELOPMENT DISORDERS USING TOCOTRIENOLS OR TOCOTRIENOLS ENRICHED EXTRACTS
|
|
PL2470168T3
(pl)
|
2009-08-26 |
2018-06-29 |
Bioelectron Technology Corporation |
Sposoby zapobiegania i leczenia niedokrwienia mózgu
|
|
EP2519232A1
(en)
|
2009-12-31 |
2012-11-07 |
Edison Pharmaceuticals, Inc. |
Treatment of leigh syndrome and leigh-like syndrome with tocotrienol quinones
|
|
SG184787A1
(en)
|
2010-03-09 |
2012-11-29 |
Edison Pharmaceuticals Inc |
Synthesis of alpha-tocopherolquinone derivatives, and methods of using the same
|
|
WO2011113018A1
(en)
|
2010-03-12 |
2011-09-15 |
Ampere Life Sciences, Inc. |
Measurement and control of biological time
|
|
US20130116336A1
(en)
|
2010-04-06 |
2013-05-09 |
William D. Shrader |
Treatment of ataxia telangiectasia
|
|
MY183449A
(en)
|
2010-04-27 |
2021-02-18 |
Bioelectron Tech Corp |
Formulations of quinones for the treatment of ophthalmic diseases
|
|
US20120101169A1
(en)
|
2010-07-14 |
2012-04-26 |
Penwest Pharmaceuticals Co. |
Methods of providing anticoagulation effects in subjects
|
|
EP2600857A4
(en)
|
2010-08-06 |
2014-06-11 |
Edison Pharmaceuticals Inc |
TREATMENT OF OCHONDRIAL DISEASES WITH NAPHTHOCHINONES
|
|
WO2012068552A1
(en)
|
2010-11-19 |
2012-05-24 |
Edison Pharmaceuticals, Inc. |
Methods for improving blood glucose control
|
|
WO2012154613A1
(en)
|
2011-05-06 |
2012-11-15 |
Edison Pharmaceuticals, Inc. |
Improved process for the preparation of d-alpha-tocotrienol from natural extracts
|
|
WO2012170773A1
(en)
|
2011-06-08 |
2012-12-13 |
Edison Pharmaceuticals, Inc. |
Adjunctive therapy for the treatment of mitochondrial disorders with quinones and naphthoquinones
|
|
EP2720689A4
(en)
|
2011-06-14 |
2014-11-26 |
Edison Pharmaceuticals Inc |
CATECHOL DERIVATIVES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH OXIDATIVE STRESS
|
|
WO2013006736A1
(en)
|
2011-07-06 |
2013-01-10 |
Edison Pharmaceuticals, Inc |
Treatment of leigh syndrome and leigh-like syndrome, including complications of sucla2 mutations, with tocotrienol quinones
|
|
JP6728520B2
(ja)
|
2011-07-06 |
2020-07-22 |
ピーティーシー セラピューティクス, インコーポレイテッド |
メチルマロン酸尿症、イソ吉草酸尿症、および他の有機酸尿症のトコトリエノールキノンによる処置
|
|
JP2014520894A
(ja)
|
2011-07-19 |
2014-08-25 |
エジソン ファーマシューティカルズ, インコーポレイテッド |
非アルファトコトリエノールの存在下でのアルファトコトリエノールの選択的酸化のための方法
|
|
CA2883879A1
(en)
|
2012-09-07 |
2014-03-13 |
Edison Pharmaceuticals, Inc. |
Quinone derivatives for use in the modulation of redox status of individuals
|
|
US8937191B2
(en)
|
2012-12-20 |
2015-01-20 |
Orochem Technologies, Inc. |
Recovery of highly pure alpha-tocotrienol from crude palm oil extract
|
|
CA3167320A1
(en)
|
2013-03-08 |
2014-09-12 |
Unilever Global Ip Limited |
Resorcinol compounds for dermatological use
|
|
US20140275045A1
(en)
|
2013-03-15 |
2014-09-18 |
Edison Pharmaceuticals, Inc. |
Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
|
|
US9868711B2
(en)
|
2013-03-15 |
2018-01-16 |
Bioelectron Technology Corporation |
Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
|
|
US10189830B2
(en)
|
2013-03-15 |
2019-01-29 |
Bioelectron Technology Corporation |
Alkyl-heteroaryl substituted quinone derivatives for treatment of oxidative stress disorders
|
|
US9296712B2
(en)
|
2013-03-15 |
2016-03-29 |
Edison Pharmaceuticals, Inc. |
Resorufin derivatives for treatment of oxidative stress disorders
|
|
US9670170B2
(en)
|
2013-03-15 |
2017-06-06 |
Bioelectron Technology Corporation |
Resorufin derivatives for treatment of oxidative stress disorders
|
|
WO2014194292A1
(en)
|
2013-05-31 |
2014-12-04 |
Edison Pharmaceuticals, Inc. |
Carboxylic acid derivatives for treatment of oxidative stress disorders
|
|
JP2018500317A
(ja)
|
2014-12-16 |
2018-01-11 |
バイオエレクトロン テクノロジー コーポレイション |
トロロックスのキラル分割のための方法
|
|
EP3233786B1
(en)
|
2014-12-16 |
2022-03-16 |
PTC Therapeutics, Inc. |
Polymorphic and amorphous forms of (r)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dienyl)butanamide
|
|
JP2018502127A
(ja)
|
2015-01-12 |
2018-01-25 |
バイオエレクトロン テクノロジー コーポレイション |
放射線被曝に対する防護のためのキノン
|
|
EP3390377A1
(en)
|
2015-12-16 |
2018-10-24 |
BioElectron Technology Corporation |
Improved methods for enriching alpha-tocotrienol from mixed tocol compositions
|
|
WO2017106803A1
(en)
|
2015-12-17 |
2017-06-22 |
Bioelectron Technology Corporation |
Flouroalkyl, flouroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
|
|
WO2017123822A1
(en)
|
2016-01-12 |
2017-07-20 |
Bioelectron Technology Corporation |
Tocopherol and tocotrienol quinone derivatives for increasing thiosulfate levels or decreasing hydrogen sulfide levels
|
|
WO2017123823A1
(en)
|
2016-01-12 |
2017-07-20 |
Bioelectron Technology Corporation |
Alkyl-, acyl-, urea-, and aza-uracil sulfide:quinone oxidoreductase inhibitors
|
|
US20190241497A1
(en)
|
2016-10-28 |
2019-08-08 |
Andrew W. Hinman |
Methods for analyzing p-hydroquinone levels and ratios
|
|
WO2018093957A1
(en)
|
2016-11-15 |
2018-05-24 |
Bioelectron Technology Corporation |
2-substituted amino-naphth[1,2-d]imidazol-5-one compounds or pharmaceutically acceptable salts thereof cross reference to related applications
|
|
WO2018129411A1
(en)
|
2017-01-06 |
2018-07-12 |
Bioelectron Technology Corporation |
Aryl- and heteroaryl-resorufin derivatives for treatment of oxidative stress disorders and liver and kidney disorders
|
|
WO2018191732A1
(en)
|
2017-04-14 |
2018-10-18 |
Bioelectron Technology Corporation |
Methods and compositions for treatment of inflammation and oxidative stress
|