DK0735033T3 - Aminomethylering af tocopheroler - Google Patents

Aminomethylering af tocopheroler

Info

Publication number
DK0735033T3
DK0735033T3 DK96104467T DK96104467T DK0735033T3 DK 0735033 T3 DK0735033 T3 DK 0735033T3 DK 96104467 T DK96104467 T DK 96104467T DK 96104467 T DK96104467 T DK 96104467T DK 0735033 T3 DK0735033 T3 DK 0735033T3
Authority
DK
Denmark
Prior art keywords
formaldehyde
mannich
prepd
mixt
tocopherol
Prior art date
Application number
DK96104467T
Other languages
English (en)
Inventor
Robert Karl Mueller
Heinz Schneider
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0735033T3 publication Critical patent/DK0735033T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK96104467T 1995-03-28 1996-03-21 Aminomethylering af tocopheroler DK0735033T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH87895 1995-03-28

Publications (1)

Publication Number Publication Date
DK0735033T3 true DK0735033T3 (da) 2000-10-23

Family

ID=4197282

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96104467T DK0735033T3 (da) 1995-03-28 1996-03-21 Aminomethylering af tocopheroler

Country Status (8)

Country Link
US (3) US6066731A (da)
EP (1) EP0735033B1 (da)
JP (1) JPH08269040A (da)
CN (1) CN1159284C (da)
AT (1) ATE194609T1 (da)
DE (1) DE59605564D1 (da)
DK (1) DK0735033T3 (da)
ES (1) ES2148616T3 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10316375A1 (de) * 2003-04-10 2004-11-04 Celanese Chemicals Europe Gmbh Verfahren zur Herstellung von N-Methyl-dialkylaminen aus sekundären Dialkylaminen und Formaldehyd
ES2553557T3 (es) * 2008-10-28 2015-12-10 Edison Pharmaceuticals, Inc. Proceso para la producción de alfa-tocotrienol y derivados
BR112013004546B1 (pt) 2010-08-26 2019-04-30 Dsm Ip Assets B.V. Processo para fabricação de 2, 3, 5 - trimetil-hidro-p-benzoquinona
CN102675275A (zh) * 2012-05-18 2012-09-19 江南大学 一种甲基化与柱层析相结合制备高含量α-生育酚的方法
EP3233776B1 (en) 2014-12-17 2019-10-23 DSM IP Assets B.V. Formation of chromanes based on intermolecular reaction of alkynes with dimethylfuran in the presence of gold(i) complexes
CN105801551B (zh) * 2014-12-29 2018-11-30 浙江新和成药业有限公司 一种维生素e醋酸酯的清洁生产方法
JP7117241B2 (ja) 2015-12-16 2022-08-12 ピーティーシー セラピューティクス， インコーポレイテッド 混合されたトコール組成物からアルファ－トコトリエノールを富化するための改良された方法
CN111675677B (zh) * 2020-07-13 2022-07-19 江苏富比亚化学品有限公司 一种n-甲基吗啉的合成工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2486539A (en) * 1946-07-19 1949-11-01 Distillation Products Inc Conversion of beta-, gamma-, and delta-tocopherol to alph-tocopherol
US2519863A (en) * 1949-05-14 1950-08-22 Eastman Kodak Co Conversion of beta-, gamma-, and delta-tocopherol to alpha-tocopherol by aminoalkylation and reduction
US4977282A (en) * 1984-04-17 1990-12-11 Henkel Corporation Production of d-alpha-tocopherol from natural plant sources
AU581216B2 (en) * 1984-04-17 1989-02-16 Henkel Corporation Production of d-alpha-tocopherol from natural plant sources
DE3741661A1 (de) * 1987-12-09 1989-06-22 Basf Lacke & Farben Bindemittel fuer die kathodische elektrotauchlackierung
EP0490815B1 (de) * 1990-12-11 1994-09-21 Ciba-Geigy Ag Verfahren zur Herstellung von symmetrischen 2,2'-Methylen-bis-benztriazolylphenolen
US5229521A (en) * 1990-12-11 1993-07-20 Ciba-Geigy Corporation Process for the preparation of symmetrical 2,2-methylenebisbenzotriazolyl phenols

Also Published As

Publication number Publication date
EP0735033A1 (de) 1996-10-02
US6066731A (en) 2000-05-23
US6252071B1 (en) 2001-06-26
EP0735033B1 (de) 2000-07-12
JPH08269040A (ja) 1996-10-15
CN1159284C (zh) 2004-07-28
DE59605564D1 (de) 2000-08-17
ES2148616T3 (es) 2000-10-16
ATE194609T1 (de) 2000-07-15
CN1138026A (zh) 1996-12-18
US6359132B1 (en) 2002-03-19

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