ES2643760T3 - Anticuerpos contra toxinas de Clostridium difficile y usos de los mismos - Google Patents
Anticuerpos contra toxinas de Clostridium difficile y usos de los mismos Download PDFInfo
- Publication number
- ES2643760T3 ES2643760T3 ES14194551.9T ES14194551T ES2643760T3 ES 2643760 T3 ES2643760 T3 ES 2643760T3 ES 14194551 T ES14194551 T ES 14194551T ES 2643760 T3 ES2643760 T3 ES 2643760T3
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- antibody
- toxin
- antibodies
- difficile
- human
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
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Landscapes
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| AR045563A1 (es) | 2003-09-10 | 2005-11-02 | Warner Lambert Co | Anticuerpos dirigidos a m-csf |
| DK1766093T3 (da) * | 2004-02-06 | 2011-10-03 | Univ Massachusetts | Antistoffer mod clostridium difficile-toksiner og anvendelse deraf |
| CA2575768C (en) * | 2004-06-28 | 2012-12-04 | Japan Science And Technology Agency | Method for screening toxin neutralizing peptide, stx2 inhibiting peptide and verotoxin neutralizing agent |
| US20090087478A1 (en) * | 2004-12-27 | 2009-04-02 | Progenics Pharmaceuticals (Nevada), Inc. | Orally Deliverable and Anti-Toxin Antibodies and Methods for Making and Using Them |
| WO2008014733A1 (de) | 2006-08-02 | 2008-02-07 | Johannes Gutenberg-Universität Mainz | Arzneimittel gegen lct-vergiftungen |
| ATE525392T1 (de) | 2007-01-30 | 2011-10-15 | Epivax Inc | Regulatorische t-zellen-epitopen sowie zusammensetzungen damit und anwendungen davon |
| AU2014201846B2 (en) * | 2007-01-30 | 2016-07-07 | Epivax, Inc. | Regulatory t cell epitopes, compositions and uses thereof |
| US20080188007A1 (en) * | 2007-02-06 | 2008-08-07 | Meridian Life Science, Inc. | Fluorescent single chain antibody and its use in detection of analytes |
| CN101363867B (zh) * | 2008-05-26 | 2012-12-19 | 北京庄笛浩禾生物医学科技有限公司 | 一种艰难梭菌a、b毒素胶体金检测试纸条及其制备方法 |
| US8420784B2 (en) * | 2008-05-27 | 2013-04-16 | Kyowa Hakko Kirin Co., Ltd. | Interleukin 10 receptor, (IL-10R) antibodies |
| DE102008029688B4 (de) * | 2008-06-24 | 2016-06-23 | Biodics Gmbh | Verfahren zum Nachweis und zur Identifikation eines varianten C. difficile Stammes in einer Probe |
| US8709428B2 (en) | 2009-02-20 | 2014-04-29 | Health Protection Agency | Antibodies to Clostridium difficile toxins |
| EP2459588B1 (de) * | 2009-07-27 | 2016-06-29 | BioDics GmbH | Verfahren zum nachweis und zur identifikation eines varianten c. difficile stammes in einer probe |
| US8889363B2 (en) | 2009-07-27 | 2014-11-18 | Biodics | Method for the detection and identification of a variant C. difficile strain in a sample |
| US20120282274A1 (en) * | 2009-11-20 | 2012-11-08 | Northshore University Health System Research Institute | Targeting of the c-terminal segment of c.difficile toxin b for improved clinical diagnosis, prevention, and treatment |
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| RU2630663C9 (ru) * | 2010-04-15 | 2017-11-29 | Проджиникс Фармасьютикалс, Инк. | Антитела для лечения ассоциированных с clostridium difficile инфекции и заболеваний |
| EP2558493B1 (en) | 2010-04-15 | 2019-09-18 | Progenics Pharmaceuticals, Inc. | Antibodies for the treatment of clostridium difficile-associated infection and disease |
| PT2753352T (pt) * | 2010-09-03 | 2017-03-08 | Intercell Usa Inc | Péptido isolado das proteínas da toxina a e da toxina b de c. difficile e suas utilizações |
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| WO2012055030A1 (en) * | 2010-10-25 | 2012-05-03 | National Research Council Of Canada | Clostridium difficile-specific antibodies and uses thereof |
| EP2661500A2 (en) * | 2010-12-29 | 2013-11-13 | Cangene Corporation | Clostridium difficile antigens |
| US8906635B2 (en) | 2011-02-28 | 2014-12-09 | Northshore University Healthsystem | Methods of diagnosing Clostridium difficile infection |
| US8481692B2 (en) | 2011-04-22 | 2013-07-09 | Wyeth Llc | Compositions relating to a mutant Clostridium difficile toxin and methods thereof |
| KR101955365B1 (ko) * | 2011-07-12 | 2019-03-07 | 필라델피아 헬스 앤드 에듀케이션 코포레이션 디/비/에이 드렉셀 유니버시티 컬리지 오브 메디슨 | 신규한 클로스트리듐 디피실(Clostridium Difficile) DNA 백신 |
| US9505847B2 (en) * | 2011-08-22 | 2016-11-29 | Cnj Holdings Inc | Clostridium difficile antibodies |
| PE20141547A1 (es) * | 2011-09-16 | 2014-10-25 | Ucb Pharma Sa | Anticuerpos neutralizantes frente a las exotoxinas principales tcda y tcdb de clostridium difficile |
| WO2013071409A1 (en) | 2011-11-18 | 2013-05-23 | National Research Council Of Canada (Nrc) | Clostridium difficile lipoteichoic acid and uses thereof |
| IN2014CN04071A (en, 2012) | 2011-12-08 | 2015-10-23 | Novartis Ag | |
| DE102011121238A1 (de) * | 2011-12-14 | 2013-06-20 | Universitätsklinikum Hamburg-Eppendorf | Einzeldomänen-antikörper gegen clostridium difficile toxine |
| AR089797A1 (es) | 2012-01-27 | 2014-09-17 | Merck Sharp & Dohme | Vacunas contra clostridum difficile que comprenden toxinas recombinantes |
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