ES2569528T3 - 4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus - Google Patents

4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus Download PDF

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ES2569528T3
ES2569528T3 ES08848610.5T ES08848610T ES2569528T3 ES 2569528 T3 ES2569528 T3 ES 2569528T3 ES 08848610 T ES08848610 T ES 08848610T ES 2569528 T3 ES2569528 T3 ES 2569528T3
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pyrazol
pyrimidin
phenylamino
carbonyl
ylamino
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Spanish (es)
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Yun-Long Li
Wenqing Yao
James D. Rodgers
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Incyte Holdings Corp
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Incyte Holdings Corp
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
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ES08848610.5T 2007-11-16 2008-11-13 4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus Active ES2569528T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98860607P 2007-11-16 2007-11-16
US988606P 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

Publications (1)

Publication Number Publication Date
ES2569528T3 true ES2569528T3 (es) 2016-05-11

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ES08848610.5T Active ES2569528T3 (es) 2007-11-16 2008-11-13 4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus

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US (1) US8309718B2 (enExample)
EP (1) EP2220068B1 (enExample)
JP (1) JP5480813B2 (enExample)
KR (1) KR101580482B1 (enExample)
CN (1) CN101910152B (enExample)
AU (1) AU2008321046B2 (enExample)
BR (1) BRPI0820544A2 (enExample)
CA (1) CA2704599C (enExample)
CO (1) CO6280420A2 (enExample)
CR (1) CR11430A (enExample)
EA (1) EA020777B1 (enExample)
EC (1) ECSP10010263A (enExample)
ES (1) ES2569528T3 (enExample)
IL (1) IL205571A (enExample)
MX (1) MX2010005300A (enExample)
MY (1) MY152948A (enExample)
NZ (1) NZ585139A (enExample)
UA (1) UA104849C2 (enExample)
WO (1) WO2009064835A1 (enExample)
ZA (1) ZA201004055B (enExample)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005105814A1 (en) * 2004-04-28 2005-11-10 Incyte Corporation Tetracyclic inhibitors of janus kinases
TWI630207B (zh) 2005-12-13 2018-07-21 英塞特控股公司 作為傑納斯激酶（ＪＡＮＵＳ ＫＩＮＡＳＥ）抑制劑之經雜芳基取代之吡咯并〔２，３-ｂ〕吡啶及吡咯并〔２，３-ｂ〕嘧啶
EP2121692B1 (en) 2006-12-22 2013-04-10 Incyte Corporation Substituted heterocycles as janus kinase inhibitors
CL2008001709A1 (es) 2007-06-13 2008-11-03 Incyte Corp Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
EP3070090B1 (en) 2007-06-13 2018-12-12 Incyte Holdings Corporation Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
FR2938537B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
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CN101910152A (zh) 2010-12-08
CN101910152B (zh) 2014-08-06
US8309718B2 (en) 2012-11-13
AU2008321046A1 (en) 2009-05-22
BRPI0820544A2 (pt) 2015-06-16
CO6280420A2 (es) 2011-05-20
EA020777B1 (ru) 2015-01-30
KR20100095582A (ko) 2010-08-31
MY152948A (en) 2014-12-15

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