ES2569528T3 - 4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus - Google Patents

4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus Download PDF

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ES2569528T3
ES2569528T3 ES08848610.5T ES08848610T ES2569528T3 ES 2569528 T3 ES2569528 T3 ES 2569528T3 ES 08848610 T ES08848610 T ES 08848610T ES 2569528 T3 ES2569528 T3 ES 2569528T3
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pyrazol
pyrimidin
phenylamino
carbonyl
ylamino
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Spanish (es)
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Yun-Long Li
Wenqing Yao
James D. Rodgers
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Incyte Holdings Corp
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Incyte Holdings Corp
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
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ES08848610.5T 2007-11-16 2008-11-13 4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus Active ES2569528T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98860607P 2007-11-16 2007-11-16
US988606P 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

Publications (1)

Publication Number Publication Date
ES2569528T3 true ES2569528T3 (es) 2016-05-11

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ES08848610.5T Active ES2569528T3 (es) 2007-11-16 2008-11-13 4-pirazolil-N-arilpirimidin-2-aminas y 4-pirazolil-N-heteroarilpirimidin-2-aminas como inhibidores de quinasas Janus

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US (1) US8309718B2 (enExample)
EP (1) EP2220068B1 (enExample)
JP (1) JP5480813B2 (enExample)
KR (1) KR101580482B1 (enExample)
CN (1) CN101910152B (enExample)
AU (1) AU2008321046B2 (enExample)
BR (1) BRPI0820544A2 (enExample)
CA (1) CA2704599C (enExample)
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CR (1) CR11430A (enExample)
EA (1) EA020777B1 (enExample)
EC (1) ECSP10010263A (enExample)
ES (1) ES2569528T3 (enExample)
IL (1) IL205571A (enExample)
MX (1) MX2010005300A (enExample)
MY (1) MY152948A (enExample)
NZ (1) NZ585139A (enExample)
UA (1) UA104849C2 (enExample)
WO (1) WO2009064835A1 (enExample)
ZA (1) ZA201004055B (enExample)

Families Citing this family (113)

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US20060106020A1 (en) * 2004-04-28 2006-05-18 Rodgers James D Tetracyclic inhibitors of Janus kinases
SI1966202T1 (sl) 2005-12-13 2012-01-31 Incyte Corp S heteroarilom substituirani pirolo (2,3-b)piridini in pirolo (2,3-b)pirimidini kot zaviralci janus kinaze
EP2121692B1 (en) 2006-12-22 2013-04-10 Incyte Corporation Substituted heterocycles as janus kinase inhibitors
CL2008001709A1 (es) 2007-06-13 2008-11-03 Incyte Corp Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
EP2173752B2 (en) 2007-06-13 2022-07-13 Incyte Holdings Corporation Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
FR2938537B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
JOP20190230A1 (ar) 2009-01-15 2017-06-16 Incyte Corp طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به
CN106967070A (zh) 2009-05-22 2017-07-21 因塞特控股公司 作为jak抑制剂的化合物
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ZA201004055B (en) 2012-09-26
IL205571A (en) 2015-09-24
UA104849C2 (uk) 2014-03-25
CR11430A (es) 2010-07-01
CN101910152A (zh) 2010-12-08
CN101910152B (zh) 2014-08-06
MX2010005300A (es) 2010-06-25
ECSP10010263A (es) 2010-07-30
KR101580482B1 (ko) 2015-12-28
EP2220068B1 (en) 2016-01-27
JP5480813B2 (ja) 2014-04-23
AU2008321046A1 (en) 2009-05-22
US8309718B2 (en) 2012-11-13
AU2008321046B2 (en) 2013-10-24
EA201070618A1 (ru) 2010-12-30
CA2704599C (en) 2015-05-12
CA2704599A1 (en) 2009-05-22
CO6280420A2 (es) 2011-05-20
BRPI0820544A2 (pt) 2015-06-16
IL205571A0 (en) 2010-12-30
WO2009064835A1 (en) 2009-05-22
NZ585139A (en) 2012-05-25
US20090318405A1 (en) 2009-12-24
HK1147476A1 (zh) 2011-08-12
EP2220068A1 (en) 2010-08-25
JP2011503194A (ja) 2011-01-27
KR20100095582A (ko) 2010-08-31
MY152948A (en) 2014-12-15

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