AU2008321046B2 - 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors - Google Patents

4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors Download PDF

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AU2008321046B2
AU2008321046B2 AU2008321046A AU2008321046A AU2008321046B2 AU 2008321046 B2 AU2008321046 B2 AU 2008321046B2 AU 2008321046 A AU2008321046 A AU 2008321046A AU 2008321046 A AU2008321046 A AU 2008321046A AU 2008321046 B2 AU2008321046 B2 AU 2008321046B2
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pyrazol
pyrim
ino
cya
pyra
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AU2008321046A1 (en
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Yun-Long Li
James D. Rodgers
Wenqing Yao
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Incyte Holdings Corp
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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AU2008321046A 2007-11-16 2008-11-13 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors Active AU2008321046B2 (en)

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Application Number Priority Date Filing Date Title
US98860607P 2007-11-16 2007-11-16
US60/988,606 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

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AU2008321046A1 AU2008321046A1 (en) 2009-05-22
AU2008321046B2 true AU2008321046B2 (en) 2013-10-24

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US (1) US8309718B2 (enExample)
EP (1) EP2220068B1 (enExample)
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KR (1) KR101580482B1 (enExample)
CN (1) CN101910152B (enExample)
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BR (1) BRPI0820544A2 (enExample)
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Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060106020A1 (en) * 2004-04-28 2006-05-18 Rodgers James D Tetracyclic inhibitors of Janus kinases
DK3184526T3 (en) 2005-12-13 2019-01-14 Incyte Holdings Corp PYRROLO [2,3-D] PYRIMIDINE DERIVATIVES AS A JANUS-KINASE INHIBITOR
US8513270B2 (en) * 2006-12-22 2013-08-20 Incyte Corporation Substituted heterocycles as Janus kinase inhibitors
CL2008001709A1 (es) 2007-06-13 2008-11-03 Incyte Corp Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
EP2740731B1 (en) 2007-06-13 2016-03-23 Incyte Holdings Corporation Crystalline salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
FR2938537B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
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ES2569528T3 (es) 2016-05-11
IL205571A0 (en) 2010-12-30
US20090318405A1 (en) 2009-12-24
CO6280420A2 (es) 2011-05-20
CN101910152A (zh) 2010-12-08
US8309718B2 (en) 2012-11-13
MY152948A (en) 2014-12-15
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CN101910152B (zh) 2014-08-06
EP2220068B1 (en) 2016-01-27
ECSP10010263A (es) 2010-07-30
KR20100095582A (ko) 2010-08-31
MX2010005300A (es) 2010-06-25
IL205571A (en) 2015-09-24
AU2008321046A1 (en) 2009-05-22
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JP2011503194A (ja) 2011-01-27
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