MX2010005300A - 4-pirazolil-n-arilpirimidin-2-aminas y 4-pirazolil-n-heteroarilpir imidin-2-aminas como inhibidores de cinasas janus. - Google Patents

4-pirazolil-n-arilpirimidin-2-aminas y 4-pirazolil-n-heteroarilpir imidin-2-aminas como inhibidores de cinasas janus.

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Publication number
MX2010005300A
MX2010005300A MX2010005300A MX2010005300A MX2010005300A MX 2010005300 A MX2010005300 A MX 2010005300A MX 2010005300 A MX2010005300 A MX 2010005300A MX 2010005300 A MX2010005300 A MX 2010005300A MX 2010005300 A MX2010005300 A MX 2010005300A
Authority
MX
Mexico
Prior art keywords
pyrazolyl
amines
arylpyrimidin
pyrimidin
heteroaryl
Prior art date
Application number
MX2010005300A
Other languages
English (en)
Spanish (es)
Inventor
James D Rodgers
Wenqing Yao
Yun-Long Li
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40380038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010005300(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of MX2010005300A publication Critical patent/MX2010005300A/es

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
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MX2010005300A 2007-11-16 2008-11-13 4-pirazolil-n-arilpirimidin-2-aminas y 4-pirazolil-n-heteroarilpir imidin-2-aminas como inhibidores de cinasas janus. MX2010005300A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98860607P 2007-11-16 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

Publications (1)

Publication Number Publication Date
MX2010005300A true MX2010005300A (es) 2010-06-25

Family

ID=40380038

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010005300A MX2010005300A (es) 2007-11-16 2008-11-13 4-pirazolil-n-arilpirimidin-2-aminas y 4-pirazolil-n-heteroarilpir imidin-2-aminas como inhibidores de cinasas janus.

Country Status (20)

Country Link
US (1) US8309718B2 (enExample)
EP (1) EP2220068B1 (enExample)
JP (1) JP5480813B2 (enExample)
KR (1) KR101580482B1 (enExample)
CN (1) CN101910152B (enExample)
AU (1) AU2008321046B2 (enExample)
BR (1) BRPI0820544A2 (enExample)
CA (1) CA2704599C (enExample)
CO (1) CO6280420A2 (enExample)
CR (1) CR11430A (enExample)
EA (1) EA020777B1 (enExample)
EC (1) ECSP10010263A (enExample)
ES (1) ES2569528T3 (enExample)
IL (1) IL205571A (enExample)
MX (1) MX2010005300A (enExample)
MY (1) MY152948A (enExample)
NZ (1) NZ585139A (enExample)
UA (1) UA104849C2 (enExample)
WO (1) WO2009064835A1 (enExample)
ZA (1) ZA201004055B (enExample)

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WO2005105814A1 (en) * 2004-04-28 2005-11-10 Incyte Corporation Tetracyclic inhibitors of janus kinases
KR101391900B1 (ko) 2005-12-13 2014-05-02 인사이트 코포레이션 야누스 키나아제 억제제로서의 헤테로아릴 치환된 피롤로［2,3-ｂ］피리딘 및 피롤로［2,3-ｂ］피리미딘
EP2121692B1 (en) * 2006-12-22 2013-04-10 Incyte Corporation Substituted heterocycles as janus kinase inhibitors
CL2008001709A1 (es) 2007-06-13 2008-11-03 Incyte Corp Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
WO2008157208A2 (en) 2007-06-13 2008-12-24 Incyte Corporation Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
FR2938537B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Derives de carbamates d'alkyl-heterocycles, leur preparation et leur application en therapeutique.
JOP20190230A1 (ar) 2009-01-15 2017-06-16 Incyte Corp طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به
TW201100429A (en) 2009-05-22 2011-01-01 Incyte Corp N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
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EP2220068A1 (en) 2010-08-25
ECSP10010263A (es) 2010-07-30
KR20100095582A (ko) 2010-08-31
AU2008321046B2 (en) 2013-10-24
CN101910152B (zh) 2014-08-06
HK1147476A1 (zh) 2011-08-12
NZ585139A (en) 2012-05-25
CA2704599C (en) 2015-05-12
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US8309718B2 (en) 2012-11-13
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