CN101910152B - 作为janus激酶抑制剂的4-吡唑基-n-芳基嘧啶-2-胺和4-吡唑基-n-杂芳基嘧啶-2-胺 - Google Patents

作为janus激酶抑制剂的4-吡唑基-n-芳基嘧啶-2-胺和4-吡唑基-n-杂芳基嘧啶-2-胺 Download PDF

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CN101910152B
CN101910152B CN200880123789.2A CN200880123789A CN101910152B CN 101910152 B CN101910152 B CN 101910152B CN 200880123789 A CN200880123789 A CN 200880123789A CN 101910152 B CN101910152 B CN 101910152B
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pyrimidine
amino
pyrazol
phenyl
cyclopentyl
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CN101910152A (zh
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Y·李
W·姚
J·D·罗杰斯
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Because Of C1-Esteraseremmer-N Parent Corp
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Incyte Corp
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CN200880123789.2A 2007-11-16 2008-11-13 作为janus激酶抑制剂的4-吡唑基-n-芳基嘧啶-2-胺和4-吡唑基-n-杂芳基嘧啶-2-胺 Active CN101910152B (zh)

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US98860607P 2007-11-16 2007-11-16
US60/988606 2007-11-16
PCT/US2008/083319 WO2009064835A1 (en) 2007-11-16 2008-11-13 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors

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CN101910152B true CN101910152B (zh) 2014-08-06

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WO2005105814A1 (en) * 2004-04-28 2005-11-10 Incyte Corporation Tetracyclic inhibitors of janus kinases
KR101391900B1 (ko) 2005-12-13 2014-05-02 인사이트 코포레이션 야누스 키나아제 억제제로서의 헤테로아릴 치환된 피롤로［2,3-ｂ］피리딘 및 피롤로［2,3-ｂ］피리미딘
EP2121692B1 (en) * 2006-12-22 2013-04-10 Incyte Corporation Substituted heterocycles as janus kinase inhibitors
CL2008001709A1 (es) 2007-06-13 2008-11-03 Incyte Corp Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
WO2008157208A2 (en) 2007-06-13 2008-12-24 Incyte Corporation Salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropanenitrile
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WO2009064835A1 (en) 2009-05-22
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JP2011503194A (ja) 2011-01-27
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