ES2300639T3 - Derivados de piridino-2,3-dipirimidina como inhibidores selectivos de kdr y fgfr. - Google Patents

Derivados de piridino-2,3-dipirimidina como inhibidores selectivos de kdr y fgfr. Download PDF

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Publication number
ES2300639T3
ES2300639T3 ES03785789T ES03785789T ES2300639T3 ES 2300639 T3 ES2300639 T3 ES 2300639T3 ES 03785789 T ES03785789 T ES 03785789T ES 03785789 T ES03785789 T ES 03785789T ES 2300639 T3 ES2300639 T3 ES 2300639T3
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ES
Spain
Prior art keywords
alkyl
phenyl
pyrimidin
substituted
propionic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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ES03785789T
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English (en)
Spanish (es)
Inventor
Jin-Jun Liu
Kin-Chun Luk
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of ES2300639T3 publication Critical patent/ES2300639T3/es
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES03785789T 2002-12-20 2003-12-11 Derivados de piridino-2,3-dipirimidina como inhibidores selectivos de kdr y fgfr. Expired - Lifetime ES2300639T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43496902P 2002-12-20 2002-12-20
US434969P 2002-12-20
US51361503P 2003-10-23 2003-10-23
US513615P 2003-10-23

Publications (1)

Publication Number Publication Date
ES2300639T3 true ES2300639T3 (es) 2008-06-16

Family

ID=32685355

Family Applications (1)

Application Number Title Priority Date Filing Date
ES03785789T Expired - Lifetime ES2300639T3 (es) 2002-12-20 2003-12-11 Derivados de piridino-2,3-dipirimidina como inhibidores selectivos de kdr y fgfr.

Country Status (15)

Country Link
US (1) US7098332B2 (enExample)
EP (1) EP1581531B1 (enExample)
JP (1) JP2006511563A (enExample)
KR (1) KR100763298B1 (enExample)
AR (1) AR042532A1 (enExample)
AT (1) ATE387445T1 (enExample)
AU (1) AU2003294830B2 (enExample)
BR (1) BR0317480A (enExample)
CA (1) CA2508951A1 (enExample)
DE (1) DE60319430T2 (enExample)
ES (1) ES2300639T3 (enExample)
MX (1) MXPA05006437A (enExample)
PL (1) PL377661A1 (enExample)
RU (1) RU2345077C2 (enExample)
WO (1) WO2004056822A1 (enExample)

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JP6898919B2 (ja) 2015-09-23 2021-07-07 ヤンセン ファーマシューティカ エヌ．ベー． 新規化合物
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US11192890B2 (en) * 2017-03-03 2021-12-07 Auckland Uniservices Limited FGFR kinase inhibitors and pharmaceutical uses
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CN110914267B (zh) * 2017-07-19 2022-07-12 江苏奥赛康药业有限公司 嘧啶并吡啶酮或者吡啶并吡啶酮类化合物及其应用
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Also Published As

Publication number Publication date
WO2004056822A1 (en) 2004-07-08
ATE387445T1 (de) 2008-03-15
KR100763298B1 (ko) 2007-10-04
KR20050088202A (ko) 2005-09-02
RU2005122901A (ru) 2006-02-27
EP1581531B1 (en) 2008-02-27
AR042532A1 (es) 2005-06-22
DE60319430D1 (de) 2008-04-10
CA2508951A1 (en) 2004-07-08
BR0317480A (pt) 2005-11-16
MXPA05006437A (es) 2005-08-19
DE60319430T2 (de) 2009-02-26
JP2006511563A (ja) 2006-04-06
AU2003294830A1 (en) 2004-07-14
RU2345077C2 (ru) 2009-01-27
EP1581531A1 (en) 2005-10-05
AU2003294830B2 (en) 2009-06-11
US20040122029A1 (en) 2004-06-24
US7098332B2 (en) 2006-08-29
PL377661A1 (pl) 2006-02-06

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