ES2298439T3 - Heterociclos biciclicos que contienen nitrogeno para uso como agentes antibacterianos. - Google Patents

Heterociclos biciclicos que contienen nitrogeno para uso como agentes antibacterianos. Download PDF

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Publication number
ES2298439T3
ES2298439T3 ES02807202T ES02807202T ES2298439T3 ES 2298439 T3 ES2298439 T3 ES 2298439T3 ES 02807202 T ES02807202 T ES 02807202T ES 02807202 T ES02807202 T ES 02807202T ES 2298439 T3 ES2298439 T3 ES 2298439T3
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ES
Spain
Prior art keywords
alkyl
amino
alkenyl
acid
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02807202T
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English (en)
Spanish (es)
Inventor
Gerald GlaxoSmithKline BROOKS
David Thomas Glaxosmithkline Davies
Graham Elgin Glaxosmithkline Jones
Roger Edward GlaxoSmithKline MARKWELL
Neil David Glaxosmithkline Pearson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of ES2298439T3 publication Critical patent/ES2298439T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES02807202T 2001-05-25 2002-05-24 Heterociclos biciclicos que contienen nitrogeno para uso como agentes antibacterianos. Expired - Lifetime ES2298439T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0112834.7A GB0112834D0 (en) 2001-05-25 2001-05-25 Medicaments
GB0112834 2001-05-25

Publications (1)

Publication Number Publication Date
ES2298439T3 true ES2298439T3 (es) 2008-05-16

Family

ID=9915342

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02807202T Expired - Lifetime ES2298439T3 (es) 2001-05-25 2002-05-24 Heterociclos biciclicos que contienen nitrogeno para uso como agentes antibacterianos.

Country Status (23)

Country Link
US (2) US7141564B2 (is)
EP (1) EP1399443B1 (is)
JP (2) JP4463565B2 (is)
KR (1) KR20040010654A (is)
CN (1) CN1535272A (is)
AR (1) AR038172A1 (is)
AT (1) ATE380812T1 (is)
AU (1) AU2002367697A1 (is)
BR (1) BR0210016A (is)
CA (1) CA2448525A1 (is)
CO (1) CO5540344A2 (is)
CZ (1) CZ20033202A3 (is)
DE (1) DE60224039T2 (is)
ES (1) ES2298439T3 (is)
GB (1) GB0112834D0 (is)
HU (1) HUP0400017A2 (is)
IL (1) IL158869A0 (is)
MX (1) MXPA03010790A (is)
NO (1) NO20035190D0 (is)
PL (1) PL367079A1 (is)
TW (1) TWI232219B (is)
WO (1) WO2003087098A1 (is)
ZA (1) ZA200308696B (is)

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JP2005519981A (ja) 2005-07-07
AR038172A1 (es) 2005-01-05
WO2003087098A1 (en) 2003-10-23
US20040171620A1 (en) 2004-09-02
DE60224039D1 (de) 2008-01-24
ZA200308696B (en) 2004-05-21
EP1399443A1 (en) 2004-03-24
PL367079A1 (en) 2005-02-21
CA2448525A1 (en) 2003-10-23
US7141564B2 (en) 2006-11-28
KR20040010654A (ko) 2004-01-31
IL158869A0 (en) 2004-05-12
BR0210016A (pt) 2004-06-15
MXPA03010790A (es) 2004-03-02
CN1535272A (zh) 2004-10-06
AU2002367697A1 (en) 2003-10-27
JP2010031057A (ja) 2010-02-12
TWI232219B (en) 2005-05-11
HUP0400017A2 (hu) 2004-06-28
EP1399443B1 (en) 2007-12-12
CO5540344A2 (es) 2005-07-29
GB0112834D0 (en) 2001-07-18
DE60224039T2 (de) 2008-11-27
CZ20033202A3 (cs) 2004-08-18
NO20035190D0 (no) 2003-11-21
JP4463565B2 (ja) 2010-05-19

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