ES2296618T3 - Derivados opticamente activos de acidos quinolin-carboxilicos que tienen sustituyentes de 7-pirrolidina que provocan actividad optica y un procedimiento para la preparacion de estos. - Google Patents

Derivados opticamente activos de acidos quinolin-carboxilicos que tienen sustituyentes de 7-pirrolidina que provocan actividad optica y un procedimiento para la preparacion de estos. Download PDF

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Publication number
ES2296618T3
ES2296618T3 ES00927899T ES00927899T ES2296618T3 ES 2296618 T3 ES2296618 T3 ES 2296618T3 ES 00927899 T ES00927899 T ES 00927899T ES 00927899 T ES00927899 T ES 00927899T ES 2296618 T3 ES2296618 T3 ES 2296618T3
Authority
ES
Spain
Prior art keywords
acid
methyl
aminomethyl
cyclopropyl
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00927899T
Other languages
English (en)
Spanish (es)
Inventor
Sung June Yoon
Yong Ho Chung
Chi Woo Lee
Jin Soo Lee
Nam Doo Kim
Yoon Ho Jin
Wan Jin Song
Ik Hoe Kim
Wang Yong Yang
Dong Rack Choi
Jung Han Shin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong Wha Pharm Co Ltd
Original Assignee
Dong Wha Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020000024657A external-priority patent/KR20010029698A/ko
Application filed by Dong Wha Pharm Ind Co Ltd filed Critical Dong Wha Pharm Ind Co Ltd
Application granted granted Critical
Publication of ES2296618T3 publication Critical patent/ES2296618T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
ES00927899T 1999-05-20 2000-05-18 Derivados opticamente activos de acidos quinolin-carboxilicos que tienen sustituyentes de 7-pirrolidina que provocan actividad optica y un procedimiento para la preparacion de estos. Expired - Lifetime ES2296618T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR99-018158 1999-05-20
KR19990018158 1999-05-20
KR20000024657 2000-05-09
KR1020000024657A KR20010029698A (ko) 1999-05-20 2000-05-09 광학활성을 유발하는 7-피롤리딘 치환체를 갖는광학활성의 퀴놀린 카르복실산 유도체 및 그의 제조방법

Publications (1)

Publication Number Publication Date
ES2296618T3 true ES2296618T3 (es) 2008-05-01

Family

ID=37040873

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00927899T Expired - Lifetime ES2296618T3 (es) 1999-05-20 2000-05-18 Derivados opticamente activos de acidos quinolin-carboxilicos que tienen sustituyentes de 7-pirrolidina que provocan actividad optica y un procedimiento para la preparacion de estos.

Country Status (11)

Country Link
US (2) US6649763B1 (enExample)
EP (1) EP1187835B1 (enExample)
JP (2) JP2003500406A (enExample)
KR (1) KR100497942B1 (enExample)
CN (1) CN1142164C (enExample)
AT (1) ATE382047T1 (enExample)
AU (1) AU757272B2 (enExample)
CA (1) CA2374767C (enExample)
DE (1) DE60037587T2 (enExample)
ES (1) ES2296618T3 (enExample)
WO (1) WO2000071541A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6589978B2 (en) * 2000-06-30 2003-07-08 Hoffman-La Roche Inc. 1-sulfonyl pyrrolidine derivatives
WO2006099167A1 (en) * 2005-03-10 2006-09-21 Theravance, Inc. Biphenyl compounds useful as muscarinic receptor antagonists
US7902227B2 (en) 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
CN101353348A (zh) * 2008-07-28 2009-01-28 南京明生医药技术有限公司 7-[4-(胺甲基)-4-氟-3-(烷氧亚氨基)吡咯烷-1-基]取代的喹啉羧酸衍生物及其制备方法
KR101468659B1 (ko) * 2009-07-27 2014-12-05 주식회사 아리바이오 Ｒ-7-(3-아미노메틸-4-메톡시이미노-3-메틸-피롤리딘-1-일)-1-시클로프로필-6-플루오로-4-옥소-1,4-디히드로-[1,8]나프티리딘-3-카르복실산 ｌ-아스파르트산염, 이의 제조방법 및 이를 포함하는 항균용 약학적 조성물
KR20220135949A (ko) 2021-03-31 2022-10-07 주식회사 이큐인베스트먼트 차트 유사도 분석을 이용한 주식 거래 인공신경망 장치 및 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0541086A1 (en) * 1991-11-08 1993-05-12 Kaken Pharmaceutical Co., Ltd. Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7
DK0688772T3 (da) * 1994-06-16 1999-11-01 Lg Chemical Ltd Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling
IT234996Y1 (it) 1994-06-22 2000-03-31 Bocchiotti Soc Ind Elettrotec Imballaggio per profilati metallici.
DE4422237A1 (de) * 1994-06-24 1996-01-04 Gruenenthal Gmbh Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe
KR0174373B1 (ko) * 1995-08-03 1999-02-18 성재갑 7-(4-아미노메틸-4-알킬-3-알킬옥심)피롤리딘 치환체를 갖는 신규 퀴놀린 카르복실산 유도체 및 그의 제조방법
DE69802692D1 (de) * 1997-06-26 2002-01-10 Dong Wha Pharm Ind Co Ltd Derivate der chinoloncarbonsäure

Also Published As

Publication number Publication date
JP2003500406A (ja) 2003-01-07
CA2374767C (en) 2007-05-15
US6753430B2 (en) 2004-06-22
ATE382047T1 (de) 2008-01-15
AU4620900A (en) 2000-12-12
JP2006232842A (ja) 2006-09-07
US20040029915A1 (en) 2004-02-12
CA2374767A1 (en) 2000-11-30
US6649763B1 (en) 2003-11-18
EP1187835A4 (en) 2003-01-29
WO2000071541A1 (en) 2000-11-30
KR100497942B1 (ko) 2005-06-29
KR20020002461A (ko) 2002-01-09
CN1358185A (zh) 2002-07-10
EP1187835B1 (en) 2007-12-26
EP1187835A1 (en) 2002-03-20
JP5276255B2 (ja) 2013-08-28
DE60037587D1 (de) 2008-02-07
DE60037587T2 (de) 2008-04-30
CN1142164C (zh) 2004-03-17
AU757272B2 (en) 2003-02-13

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