DE69802692D1 - Derivate der chinoloncarbonsäure - Google Patents

Derivate der chinoloncarbonsäure

Info

Publication number
DE69802692D1
DE69802692D1 DE69802692T DE69802692T DE69802692D1 DE 69802692 D1 DE69802692 D1 DE 69802692D1 DE 69802692 T DE69802692 T DE 69802692T DE 69802692 T DE69802692 T DE 69802692T DE 69802692 D1 DE69802692 D1 DE 69802692D1
Authority
DE
Germany
Prior art keywords
chinolonic
derivatives
carbonic acid
carbonic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69802692T
Other languages
English (en)
Inventor
Sung-Joon Yoon
Yong-Ho Chung
Chi-Woo Lee
Yoon-Seok Oh
Nam-Doo Kim
Jae-Kyung Lim
Yoon-Ho Jin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dong Wha Pharm Co Ltd
Original Assignee
Dong Wha Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Wha Pharm Ind Co Ltd filed Critical Dong Wha Pharm Ind Co Ltd
Application granted granted Critical
Publication of DE69802692D1 publication Critical patent/DE69802692D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69802692T 1997-06-26 1998-06-26 Derivate der chinoloncarbonsäure Expired - Lifetime DE69802692D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR19970027806 1997-06-26
KR19980001609 1998-01-20
PCT/KR1998/000185 WO1999000393A1 (en) 1997-06-26 1998-06-26 Quinolone carboxylic acid derivatives

Publications (1)

Publication Number Publication Date
DE69802692D1 true DE69802692D1 (de) 2002-01-10

Family

ID=26632876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69802692T Expired - Lifetime DE69802692D1 (de) 1997-06-26 1998-06-26 Derivate der chinoloncarbonsäure

Country Status (8)

Country Link
US (2) US6313299B1 (de)
EP (1) EP0994878B1 (de)
JP (1) JP3280388B2 (de)
KR (1) KR100566346B1 (de)
CN (1) CN1114607C (de)
AU (1) AU7940598A (de)
DE (1) DE69802692D1 (de)
WO (1) WO1999000393A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60037587T2 (de) * 1999-05-20 2008-04-30 Dong Wha Pharmaceutical Industrial Co. Ltd. Optisch aktive quinolin-carbonsäure-derivate mit einem 7-pyrrolidin-substituenten, der die optische aktivität verursacht und ein verfahren zu seiner herstellung
CA2663947A1 (en) * 2006-09-15 2008-03-20 Schering Corporation Azetidine and azetidone derivatives useful in treating pain and disorders of lipid metabolism
CA2663500A1 (en) 2006-09-15 2008-03-20 Schering Corporation Spiro-condensed azetidine derivatives useful in treating pain, diabetes and disorders of lipid metabolism
JP2010503679A (ja) 2006-09-15 2010-02-04 シェーリング コーポレイション 疼痛および脂質代謝障害を処置する際に有用なアゼチジン誘導体およびアゼチドン誘導体
DK2134712T3 (da) * 2007-04-13 2013-11-18 Dong Wha Pharm Co Ltd Aspartat af 1-cyclopropyl-6-fluoro-7-(8-methoxyimino-2,6-diaza-spiro(3, 4)oct-6-yl)-4-oxo-1,4-dihydro-(1,8) naphthyridin-3-karboxylsyre, fremgangsmåde til fremstilling af samme og antimikrobielt farmaceutisk sammensætning omfattende samme
CN101974578B (zh) * 2010-10-21 2014-06-11 杭州师范大学 一种复合酶催化水解制备喹诺酮类羧酸中间体的方法
TWI583680B (zh) 2011-08-31 2017-05-21 大塚製藥股份有限公司 喹啉酮化合物
KR101882800B1 (ko) 2012-02-28 2018-08-01 삼성전자주식회사 무선 전력 수신기 및 그 제어 방법
KR101646324B1 (ko) * 2014-03-04 2016-08-05 동화약품주식회사 1-시클로프로필-6-플루오로-7-(8-메톡시이미노-2,6-디아자-스피로[3,4]옥트-6-일)-4-옥소-1,4-디히드로-[1,8]나프티리딘-3-카르복실산 디-아스파르트산염의 수화물 및 이를 포함하는 항균활성 조성물
CN103922987B (zh) * 2014-05-04 2016-09-28 苏州天马精细化学品股份有限公司 一种扎布沙星中间体及其合成方法
KR102213991B1 (ko) * 2014-05-20 2021-02-09 동화약품주식회사 개선된 자보플록사신의 제조방법
CN108570061B (zh) * 2018-08-06 2021-03-02 沈阳林特制药有限公司 扎布沙星的制备方法
MX2021004624A (es) * 2018-10-24 2021-05-27 Araxes Pharma Llc Derivados de 2-(2-acriloil-2,6-diazaspiro[3.4]octan-6-il)-6-(1h-in dazol-4-il)-benzonitrilo y compuestos relacionados como inhibidores de la proteina kras mutante g12c para inhibir metastasis de tumor.

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53141286A (en) 1977-05-16 1978-12-08 Kyorin Seiyaku Kk Novel substituted quinolinecarboxylic acid
US4670444B1 (en) 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
US4620007A (en) 1980-09-03 1986-10-28 Bayer Aktiengesellschaft 6-fluoro-7-chloro-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
US4638067A (en) 1982-09-09 1987-01-20 Warner-Lambert Co. Antibacterial agents
DE3318145A1 (de) 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4573170A (en) * 1984-02-15 1986-02-25 Westinghouse Electric Corp. Apparatus and method for sampling multiple carrier signals
JPS62174053A (ja) 1984-11-14 1987-07-30 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物及び該化合物を含有する抗菌剤
AT392789B (de) 1985-01-23 1991-06-10 Toyama Chemical Co Ltd Verfahren zur herstellung von 1-substituierten aryl-1,4-dihydro-4-oxonaphthyridinderivaten
US4617308A (en) 1985-01-25 1986-10-14 Warner-Lambert Company 7-substituted amino-1-aryl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids and derivatives thereof as antibacterial agents
CA1336090C (en) 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
KR960011370B1 (ko) * 1991-12-31 1996-08-22 재단법인 한국화학연구소 스피로알킬아민 유도체와 그의 제조방법
JPH0649060A (ja) * 1992-07-23 1994-02-22 Hokuriku Seiyaku Co Ltd ５−アミノ−７−（５−アザスピロ〔２，４〕ヘプタン−５−イル）キノリン−３−カルボン酸誘導体
JPH0649059A (ja) * 1992-07-23 1994-02-22 Hokuriku Seiyaku Co Ltd ７−（５−アザスピロ〔２，４〕ヘプタン−５−イル）−８−アルコキシキノリン−３−カルボン酸誘導体
JPH06199834A (ja) * 1993-01-08 1994-07-19 Hokuriku Seiyaku Co Ltd 光学活性な８−メトキシキノリン−３−カルボン酸誘導体
JP2758722B2 (ja) 1993-08-13 1998-05-28 ドング ホワ ファーマシューチカル インダストリアル カンパニー，リミテッド 新規キノロンカルボン酸誘導体
JPH0770110A (ja) * 1993-08-27 1995-03-14 Hokuriku Seiyaku Co Ltd ５，８−ジメチルキノリン−３−カルボン酸誘導体
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
US5576321A (en) 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems

Also Published As

Publication number Publication date
US20020035258A1 (en) 2002-03-21
KR100566346B1 (ko) 2006-11-10
EP0994878B1 (de) 2001-11-28
KR19990007390A (ko) 1999-01-25
CN1259952A (zh) 2000-07-12
EP0994878A1 (de) 2000-04-26
AU7940598A (en) 1999-01-19
WO1999000393A1 (en) 1999-01-07
JP2000513378A (ja) 2000-10-10
US6313299B1 (en) 2001-11-06
JP3280388B2 (ja) 2002-05-13
CN1114607C (zh) 2003-07-16
US6552196B2 (en) 2003-04-22

Similar Documents

Publication Publication Date Title
DE69822839D1 (de) Derivate von aryloxyarylsulfonylamino hydroxyaminsäuren
EE200000725A (et) Uued 3-arüülpropaanhappe derivaadid ja nende analoogid
NO20001962D0 (no) Terapeutisk anvendelse av kinolinderivater
CY2012029I2 (el) Nεα μορφη της 5-ομεπραζολης
ATE248812T1 (de) Arylsulfonylhydroxamsäurederivate
IS2325B (is) Örgerðar samsetningar epleróns
DE69706292D1 (de) Chinazoline derivate
DE69940306D1 (de) Varianten der phytase
NO993836D0 (no) Arylsulfonyl-hydroksamsyre-derivater
BR9510256A (pt) Derivados de ácido 3-aril-tetrônico
DK1070069T3 (da) Bicycliske hydroxaminsyrederivater
DE69613368D1 (de) Chinazolin derivate
DE69613367D1 (de) Chinazolin derivate
NO20001926L (no) Iso-CBI- og iso-CI-analoger av CC-1065 og duocarmycinene
IT1304793B1 (it) Miscela di stabilizzanti
DE69603269D1 (de) Derivate von inulin
ATE277917T1 (de) Alkylaminobenzothiazole und -benzoxazole derivate
DE69802692D1 (de) Derivate der chinoloncarbonsäure
DE69805334D1 (de) Derivate des vitamin e
DE69928262D1 (de) Substituierte chinazoline derivate
IT1304794B1 (it) Miscela di stabilizzanti
DE69908614D1 (de) Herstellung von n-substituierten-hydroxycycloalkylamin-derivaten
ID24677A (id) Kombinasi senyawa aktif fungisidal
ID29966A (id) Sulfoniloksazolamina-sulfoniloksazolamina sebagai senyawa-senyawa aktif terapi
DE69904738D1 (de) 2-phenylpyran-4-one derivate

Legal Events

Date Code Title Description
8332 No legal effect for de