DE60037587D1 - Optisch aktive quinolin-carbonsäure-derivate mit einem 7-pyrrolidin-substituenten, der die optische aktivität verursacht und ein verfahren zu seiner herstellung - Google Patents
Optisch aktive quinolin-carbonsäure-derivate mit einem 7-pyrrolidin-substituenten, der die optische aktivität verursacht und ein verfahren zu seiner herstellungInfo
- Publication number
- DE60037587D1 DE60037587D1 DE60037587T DE60037587T DE60037587D1 DE 60037587 D1 DE60037587 D1 DE 60037587D1 DE 60037587 T DE60037587 T DE 60037587T DE 60037587 T DE60037587 T DE 60037587T DE 60037587 D1 DE60037587 D1 DE 60037587D1
- Authority
- DE
- Germany
- Prior art keywords
- carboxylic acid
- optically active
- acid derivatives
- optical activity
- pyrrolidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LOAUVZALPPNFOQ-UHFFFAOYSA-N quinaldic acid Chemical class C1=CC=CC2=NC(C(=O)O)=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-N 0.000 title abstract 3
- 230000003287 optical effect Effects 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 231100001085 no phototoxicity Toxicity 0.000 abstract 1
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical group C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR9918158 | 1999-05-20 | ||
| KR19990018158 | 1999-05-20 | ||
| KR1020000024657A KR20010029698A (ko) | 1999-05-20 | 2000-05-09 | 광학활성을 유발하는 7-피롤리딘 치환체를 갖는광학활성의 퀴놀린 카르복실산 유도체 및 그의 제조방법 |
| KR20000024657 | 2000-05-09 | ||
| PCT/KR2000/000487 WO2000071541A1 (en) | 1999-05-20 | 2000-05-18 | Optically active quinoline carboxylic acid derivatives having 7-pyrrolidine substitutes causing optical activity and a process for preparing thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60037587D1 true DE60037587D1 (de) | 2008-02-07 |
| DE60037587T2 DE60037587T2 (de) | 2008-04-30 |
Family
ID=37040873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60037587T Expired - Lifetime DE60037587T2 (de) | 1999-05-20 | 2000-05-18 | Optisch aktive quinolin-carbonsäure-derivate mit einem 7-pyrrolidin-substituenten, der die optische aktivität verursacht und ein verfahren zu seiner herstellung |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6649763B1 (de) |
| EP (1) | EP1187835B1 (de) |
| JP (2) | JP2003500406A (de) |
| KR (1) | KR100497942B1 (de) |
| CN (1) | CN1142164C (de) |
| AT (1) | ATE382047T1 (de) |
| AU (1) | AU757272B2 (de) |
| CA (1) | CA2374767C (de) |
| DE (1) | DE60037587T2 (de) |
| ES (1) | ES2296618T3 (de) |
| WO (1) | WO2000071541A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6589978B2 (en) * | 2000-06-30 | 2003-07-08 | Hoffman-La Roche Inc. | 1-sulfonyl pyrrolidine derivatives |
| EP1866284A1 (de) * | 2005-03-10 | 2007-12-19 | Theravance, Inc. | Biphenylverbindungen als muskarinrezeptorantagonisten |
| US7902227B2 (en) | 2007-07-27 | 2011-03-08 | Janssen Pharmaceutica Nv. | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents |
| CN101353348A (zh) * | 2008-07-28 | 2009-01-28 | 南京明生医药技术有限公司 | 7-[4-(胺甲基)-4-氟-3-(烷氧亚氨基)吡咯烷-1-基]取代的喹啉羧酸衍生物及其制备方法 |
| KR101468659B1 (ko) | 2009-07-27 | 2014-12-05 | 주식회사 아리바이오 | Ｒ-7-(3-아미노메틸-4-메톡시이미노-3-메틸-피롤리딘-1-일)-1-시클로프로필-6-플루오로-4-옥소-1,4-디히드로-[1,8]나프티리딘-3-카르복실산 ｌ-아스파르트산염, 이의 제조방법 및 이를 포함하는 항균용 약학적 조성물 |
| KR20220135949A (ko) | 2021-03-31 | 2022-10-07 | 주식회사 이큐인베스트먼트 | 차트 유사도 분석을 이용한 주식 거래 인공신경망 장치 및 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0541086A1 (de) * | 1991-11-08 | 1993-05-12 | Kaken Pharmaceutical Co., Ltd. | Antibakterielle 6-Fluoro-Chinolone mit einer Oximegruppe an dem Substituent in Position 7 |
| EP0688772B1 (de) * | 1994-06-16 | 1999-05-06 | LG Chemical Limited | Chinolincarbonsäurederivate mit 7-(4-Amino-methyl-3-oxim)-pyrrolidin-Substituenten und Verfahren zu ihrer Herstellung |
| IT234996Y1 (it) | 1994-06-22 | 2000-03-31 | Bocchiotti Soc Ind Elettrotec | Imballaggio per profilati metallici. |
| DE4422237A1 (de) * | 1994-06-24 | 1996-01-04 | Gruenenthal Gmbh | Verwendung von Lactamverbindungen als pharmazeutische Wirkstoffe |
| KR0174373B1 (ko) * | 1995-08-03 | 1999-02-18 | 성재갑 | 7-(4-아미노메틸-4-알킬-3-알킬옥심)피롤리딘 치환체를 갖는 신규 퀴놀린 카르복실산 유도체 및 그의 제조방법 |
| CN1114607C (zh) | 1997-06-26 | 2003-07-16 | 同和药品工业株式会社 | 喹诺酮羧酸衍生物 |
-
2000
- 2000-05-18 ES ES00927899T patent/ES2296618T3/es not_active Expired - Lifetime
- 2000-05-18 AT AT00927899T patent/ATE382047T1/de not_active IP Right Cessation
- 2000-05-18 CA CA002374767A patent/CA2374767C/en not_active Expired - Lifetime
- 2000-05-18 CN CNB008094705A patent/CN1142164C/zh not_active Expired - Lifetime
- 2000-05-18 DE DE60037587T patent/DE60037587T2/de not_active Expired - Lifetime
- 2000-05-18 US US09/979,644 patent/US6649763B1/en not_active Expired - Lifetime
- 2000-05-18 EP EP00927899A patent/EP1187835B1/de not_active Expired - Lifetime
- 2000-05-18 WO PCT/KR2000/000487 patent/WO2000071541A1/en active IP Right Grant
- 2000-05-18 KR KR10-2001-7014647A patent/KR100497942B1/ko active IP Right Grant
- 2000-05-18 JP JP2000619797A patent/JP2003500406A/ja not_active Withdrawn
- 2000-05-18 AU AU46209/00A patent/AU757272B2/en not_active Ceased
-
2003
- 2003-06-20 US US10/600,631 patent/US6753430B2/en not_active Expired - Lifetime
-
2006
- 2006-03-27 JP JP2006084397A patent/JP5276255B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20040029915A1 (en) | 2004-02-12 |
| EP1187835A1 (de) | 2002-03-20 |
| US6649763B1 (en) | 2003-11-18 |
| EP1187835A4 (de) | 2003-01-29 |
| EP1187835B1 (de) | 2007-12-26 |
| CA2374767C (en) | 2007-05-15 |
| KR100497942B1 (ko) | 2005-06-29 |
| WO2000071541A1 (en) | 2000-11-30 |
| US6753430B2 (en) | 2004-06-22 |
| JP5276255B2 (ja) | 2013-08-28 |
| KR20020002461A (ko) | 2002-01-09 |
| CN1358185A (zh) | 2002-07-10 |
| ES2296618T3 (es) | 2008-05-01 |
| AU757272B2 (en) | 2003-02-13 |
| DE60037587T2 (de) | 2008-04-30 |
| AU4620900A (en) | 2000-12-12 |
| CA2374767A1 (en) | 2000-11-30 |
| ATE382047T1 (de) | 2008-01-15 |
| CN1142164C (zh) | 2004-03-17 |
| JP2006232842A (ja) | 2006-09-07 |
| JP2003500406A (ja) | 2003-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: EU BIOTECH DEVELOPMENT LTD., GLASGOW, GB |