DE60122539D1 - Neues verfahren zur herstellung einer chinolon-carbonsäure - Google Patents

Neues verfahren zur herstellung einer chinolon-carbonsäure

Info

Publication number
DE60122539D1
DE60122539D1 DE60122539T DE60122539T DE60122539D1 DE 60122539 D1 DE60122539 D1 DE 60122539D1 DE 60122539 T DE60122539 T DE 60122539T DE 60122539 T DE60122539 T DE 60122539T DE 60122539 D1 DE60122539 D1 DE 60122539D1
Authority
DE
Germany
Prior art keywords
chinolon
producing
carboxylic acid
new method
4alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60122539T
Other languages
English (en)
Other versions
DE60122539T2 (de
Inventor
Yuncai Wang
Rongye Chen
Haijun Nan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lynchem Co Ltd
Original Assignee
Lynchem Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lynchem Co Ltd filed Critical Lynchem Co Ltd
Publication of DE60122539D1 publication Critical patent/DE60122539D1/de
Application granted granted Critical
Publication of DE60122539T2 publication Critical patent/DE60122539T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/807—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen all halogen atoms bound to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60122539T 2000-08-16 2001-07-06 Verfahren zur Herstellung von Chinolincarbonsäuren Expired - Lifetime DE60122539T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN00123446 2000-08-16
CN00123446.3A CN1338455A (zh) 2000-08-16 2000-08-16 新的喹诺酮羧酸的制备方法
PCT/CN2001/001156 WO2002059094A1 (fr) 2000-08-16 2001-07-06 Nouveau procede de preparation d'un acide quinolone-carboxylique

Publications (2)

Publication Number Publication Date
DE60122539D1 true DE60122539D1 (de) 2006-10-05
DE60122539T2 DE60122539T2 (de) 2007-05-03

Family

ID=4589879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60122539T Expired - Lifetime DE60122539T2 (de) 2000-08-16 2001-07-06 Verfahren zur Herstellung von Chinolincarbonsäuren

Country Status (7)

Country Link
US (1) US6699992B2 (de)
EP (1) EP1319656B1 (de)
JP (1) JP2004517149A (de)
CN (2) CN1338455A (de)
AT (1) ATE337304T1 (de)
DE (1) DE60122539T2 (de)
WO (1) WO2002059094A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100519158B1 (ko) * 2002-12-21 2005-10-06 주식회사유한양행 퀴놀론 카르복실레이트 유도체의 제조방법
US8187483B2 (en) * 2006-08-11 2012-05-29 Jason Plumhoff Method to minimize CD etch bias
US8063066B2 (en) 2007-03-19 2011-11-22 Takeda Pharmaceutical Company Limited MAPK/ERK kinase inhibitors
US20090043646A1 (en) * 2007-08-06 2009-02-12 International Business Machines Corporation System and Method for the Automated Capture and Clustering of User Activities
CN102260172B (zh) * 2011-03-30 2013-11-06 山东先达农化股份有限公司 一种2-氯-5-烷基羰基乙酰基-4氟苯氧乙酰化合物的制备方法
CN103450068B (zh) * 2012-05-27 2015-09-16 重庆常捷医药化工有限公司 一种齐拉西酮中间体的合成方法
CN107987074B (zh) * 2017-10-27 2020-12-29 浙江美诺华药物化学有限公司 一种普拉沙星的合成方法
CN111989314B (zh) 2018-04-25 2024-04-30 拜耳动物保健有限责任公司 喹诺酮甲酸酯水解的方法
CN114933543B (zh) * 2022-07-21 2022-10-28 山东国邦药业有限公司 一种3-环丙胺基-2-(2,4-二氯-5-氟苯甲酰基)丙烯酸甲酯的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
NZ225926A (en) * 1987-09-08 1990-04-26 Sterling Drug Inc 7-pyridinyl-4-oxo-3-quinolinecarboxylic acid derivatives, and pharmaceutical compositions
US5075319A (en) * 1987-09-08 1991-12-24 Sterling Drug Inc. Pyridinyl-quinolone compounds, their preparation and use
ES2049640B1 (es) * 1992-06-18 1994-12-16 Genesis Para La Investigacion Procedimiento paras la preparacion de acidos quinolin carboxilicos.
ATE190972T1 (de) * 1994-08-02 2000-04-15 Procter & Gamble Verfahren zur herstellung von antimikrobiellen verbindungen
JP2000119221A (ja) * 1998-10-14 2000-04-25 Kyorin Pharmaceut Co Ltd （２，４，５−トリフルオロ−３−メトキシベンゾイル）酢酸エステル誘導体の製造方法及びその製造中間体

Also Published As

Publication number Publication date
WO2002059094A1 (fr) 2002-08-01
EP1319656A1 (de) 2003-06-18
CN1219769C (zh) 2005-09-21
DE60122539T2 (de) 2007-05-03
EP1319656B1 (de) 2006-08-23
JP2004517149A (ja) 2004-06-10
CN1338455A (zh) 2002-03-06
EP1319656A4 (de) 2004-09-29
ATE337304T1 (de) 2006-09-15
US6699992B2 (en) 2004-03-02
CN1447797A (zh) 2003-10-08
US20030166936A1 (en) 2003-09-04

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