ES2277743B2 - Nanoparticulas que comprenden quitosano y ciclodextrina. - Google Patents

Nanoparticulas que comprenden quitosano y ciclodextrina. Download PDF

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Publication number
ES2277743B2
ES2277743B2 ES200501331A ES200501331A ES2277743B2 ES 2277743 B2 ES2277743 B2 ES 2277743B2 ES 200501331 A ES200501331 A ES 200501331A ES 200501331 A ES200501331 A ES 200501331A ES 2277743 B2 ES2277743 B2 ES 2277743B2
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ES
Spain
Prior art keywords
cyclodextrin
chitosan
nanoparticles
biologically active
active molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200501331A
Other languages
English (en)
Spanish (es)
Other versions
ES2277743A1 (es
Inventor
Maria Jose Alonso Fernandez
Marcos Garcia Fuentes
Francesca Maestrelli
Paola Mura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidade de Santiago de Compostela
Original Assignee
Universidade de Santiago de Compostela
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ES200501331A priority Critical patent/ES2277743B2/es
Application filed by Universidade de Santiago de Compostela filed Critical Universidade de Santiago de Compostela
Priority to CN2006800208889A priority patent/CN101217947B/zh
Priority to CA002610403A priority patent/CA2610403A1/en
Priority to US11/916,283 priority patent/US20080220030A1/en
Priority to KR1020077029819A priority patent/KR20080019014A/ko
Priority to BRPI0613234-0A priority patent/BRPI0613234A2/pt
Priority to EP06778444A priority patent/EP1891943A2/en
Priority to AU2006254128A priority patent/AU2006254128A1/en
Priority to PCT/ES2006/000322 priority patent/WO2006128937A2/es
Priority to JP2008514129A priority patent/JP5191884B2/ja
Publication of ES2277743A1 publication Critical patent/ES2277743A1/es
Priority to IL187696A priority patent/IL187696A0/en
Application granted granted Critical
Publication of ES2277743B2 publication Critical patent/ES2277743B2/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
ES200501331A 2005-06-02 2005-06-02 Nanoparticulas que comprenden quitosano y ciclodextrina. Expired - Fee Related ES2277743B2 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ES200501331A ES2277743B2 (es) 2005-06-02 2005-06-02 Nanoparticulas que comprenden quitosano y ciclodextrina.
PCT/ES2006/000322 WO2006128937A2 (es) 2005-06-02 2006-06-01 Nanoparticulas que comprenden quitosano y ciclodextrina
US11/916,283 US20080220030A1 (en) 2005-06-02 2006-06-01 Nanoparticles Comprising Chitosan and Cyclodextrin
KR1020077029819A KR20080019014A (ko) 2005-06-02 2006-06-01 키토산 및 사이클로덱스트린을 포함하는 나노입자
BRPI0613234-0A BRPI0613234A2 (pt) 2005-06-02 2006-06-01 sistema que inclui nanopartìculas para a libertação de moléculas biologicamente ativas, composição farmacêutica, composição cosmética, vacina, procedimento para obtenção de um sistema para a libertação controlada de molécula biologicamente ativa, procedimento para a obtenção de nanopartìculas e utilização de um sistema
EP06778444A EP1891943A2 (en) 2005-06-02 2006-06-01 Nanoparticles comprising chitosan and cyclodextrin
CN2006800208889A CN101217947B (zh) 2005-06-02 2006-06-01 包含壳聚糖和环糊精的纳米颗粒
CA002610403A CA2610403A1 (en) 2005-06-02 2006-06-01 Nanoparticles comprising chitosan and cyclodextrin
JP2008514129A JP5191884B2 (ja) 2005-06-02 2006-06-01 キトサンおよびシクロデキストリンを含んでなるナノ粒子
AU2006254128A AU2006254128A1 (en) 2005-06-02 2006-06-01 Nanoparticles comprising chitosan and cyclodextrin
IL187696A IL187696A0 (en) 2005-06-02 2007-11-27 Nanoparticles comprising chitosan and cyclodextrin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200501331A ES2277743B2 (es) 2005-06-02 2005-06-02 Nanoparticulas que comprenden quitosano y ciclodextrina.

Publications (2)

Publication Number Publication Date
ES2277743A1 ES2277743A1 (es) 2007-07-16
ES2277743B2 true ES2277743B2 (es) 2008-12-16

Family

ID=37482018

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200501331A Expired - Fee Related ES2277743B2 (es) 2005-06-02 2005-06-02 Nanoparticulas que comprenden quitosano y ciclodextrina.

Country Status (11)

Country Link
US (1) US20080220030A1 (enExample)
EP (1) EP1891943A2 (enExample)
JP (1) JP5191884B2 (enExample)
KR (1) KR20080019014A (enExample)
CN (1) CN101217947B (enExample)
AU (1) AU2006254128A1 (enExample)
BR (1) BRPI0613234A2 (enExample)
CA (1) CA2610403A1 (enExample)
ES (1) ES2277743B2 (enExample)
IL (1) IL187696A0 (enExample)
WO (1) WO2006128937A2 (enExample)

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ES2310122B1 (es) * 2007-04-20 2009-10-30 Instituto Cientifico Y Tecnologico De Navarra, S.A Nanoparticulas que comprenden una ciclodextrina y una molecula biologicamente activa y sus aplicaciones.
WO2009048958A2 (en) * 2007-10-08 2009-04-16 The Board Of Regents Of The University Of Texas System Methods and compositions involving chitosan nanoparticles
UA90013C2 (ru) * 2008-03-19 2010-03-25 Давид Анатолійович Нога Фармацевтическая композиция, содержащая инсулин, и способ его получения
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JP5804453B2 (ja) * 2009-05-14 2015-11-04 国立大学法人 東京大学 結晶性ポリオール微粒子及びその調製方法
KR101342641B1 (ko) * 2009-06-25 2013-12-20 주식회사 바이오리더스 폴리감마글루탐산-키토산 나노입자를 함유하는 면역보강제 조성물
US8372877B2 (en) * 2010-04-16 2013-02-12 Cumberland Pharmaceuticals Stabilized statin formulations
CN102008450B (zh) * 2010-12-10 2013-01-30 杭州艾瑞莎生物医药科技有限公司 一种药物-环糊精纳米颗粒及其制备方法
CN102416000B (zh) * 2011-12-13 2013-04-10 张维芬 一种用于肺吸入的壳聚糖季铵盐大孔微球及其制备方法
FR2989001B1 (fr) 2012-04-06 2017-07-21 Centre Nat Rech Scient Microparticules et nanoparticules constituees de polysaccharides hydrophobises et d'une alpha-cyclodextrine
CN102908315B (zh) * 2012-11-02 2014-06-04 上海现代药物制剂工程研究中心有限公司 小分子干扰核糖核酸的壳聚糖纳米粒传递系统及制备方法
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CN108849995B (zh) * 2018-06-12 2020-06-30 甘肃省科学院生物研究所 黄帚橐吾提取物纳米杀虫剂及其制备方法
CN109012629B (zh) * 2018-08-16 2021-07-30 南京大学 一种制备磁性羧甲基β-环糊精聚合物的方法及其应用
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CN113773161B (zh) * 2021-10-12 2022-12-09 龙蟒大地农业有限公司 一种圆颗粒钾肥及其制备方法
CN113995834A (zh) * 2021-11-08 2022-02-01 江南大学 一种基于环糊精接枝壳聚糖的疫苗、制备方法及应用
CN114176157A (zh) * 2021-11-15 2022-03-15 安佑生物科技集团股份有限公司 一种抑制畜禽球虫的绿色添加剂、制备方法及应用
CN114904493B (zh) * 2022-03-31 2024-09-06 中科院广州化学有限公司 一种离子交联β-环糊精聚合物及其制备方法与应用
CN114451426B (zh) * 2022-04-13 2022-07-15 山东健源生物科技有限公司 用于畜禽环境改良的消毒抑菌生物复合制剂及其制备方法
CN115595809A (zh) * 2022-10-25 2023-01-13 东莞市伊时针织印花有限公司（Cn） 一种用于蛋白质纤维织物的酸性染料及其制备方法
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Also Published As

Publication number Publication date
CN101217947A (zh) 2008-07-09
IL187696A0 (en) 2008-08-07
JP2008542342A (ja) 2008-11-27
BRPI0613234A2 (pt) 2010-12-28
KR20080019014A (ko) 2008-02-29
AU2006254128A1 (en) 2006-12-07
CA2610403A1 (en) 2006-12-07
WO2006128937A3 (es) 2007-02-15
CN101217947B (zh) 2012-04-25
US20080220030A1 (en) 2008-09-11
EP1891943A2 (en) 2008-02-27
JP5191884B2 (ja) 2013-05-08
WO2006128937A2 (es) 2006-12-07
ES2277743A1 (es) 2007-07-16

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