ES2117964T3 - Nuevas mezclas de gases propelentes y su uso en preparaciones medicas. - Google Patents

Nuevas mezclas de gases propelentes y su uso en preparaciones medicas.

Info

Publication number
ES2117964T3
ES2117964T3 ES91903275T ES91903275T ES2117964T3 ES 2117964 T3 ES2117964 T3 ES 2117964T3 ES 91903275 T ES91903275 T ES 91903275T ES 91903275 T ES91903275 T ES 91903275T ES 2117964 T3 ES2117964 T3 ES 2117964T3
Authority
ES
Spain
Prior art keywords
medical preparations
new mixtures
propellent gases
new
propellent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91903275T
Other languages
English (en)
Inventor
Hans-Hermann Weil
Ottfried Daab
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6399400&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2117964(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Application granted granted Critical
Publication of ES2117964T3 publication Critical patent/ES2117964T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

NUEVAS MEZCLAS DE GASES PROPULSORES VENTAJOSAS QUE CONTIENEN DOS O MAS COMPONENTES, DE LOS QUE AL MENOS UNO ES UN ALCANO BAJO PARCIALMENTE FLUORIFICADO Y QUE PUEDEN APLICARSE EN PREPARADOS MEDICOS.
ES91903275T 1990-02-03 1991-01-31 Nuevas mezclas de gases propelentes y su uso en preparaciones medicas. Expired - Lifetime ES2117964T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4003272A DE4003272A1 (de) 1990-02-03 1990-02-03 Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen

Publications (1)

Publication Number Publication Date
ES2117964T3 true ES2117964T3 (es) 1998-09-01

Family

ID=6399400

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91903275T Expired - Lifetime ES2117964T3 (es) 1990-02-03 1991-01-31 Nuevas mezclas de gases propelentes y su uso en preparaciones medicas.

Country Status (24)

Country Link
US (1) US6413497B1 (es)
EP (1) EP0514415B1 (es)
JP (1) JP3497161B2 (es)
AT (1) ATE165863T1 (es)
AU (1) AU650001B2 (es)
CA (1) CA2075058C (es)
CZ (1) CZ286691B6 (es)
DE (2) DE4003272A1 (es)
DK (1) DK0514415T3 (es)
ES (1) ES2117964T3 (es)
FI (1) FI102905B (es)
HK (1) HK1010786A1 (es)
HR (1) HRP940735B1 (es)
HU (2) HU9202509D0 (es)
IE (2) IE910351A1 (es)
IL (1) IL97028A (es)
NO (1) NO302419B1 (es)
NZ (1) NZ236973A (es)
PT (1) PT96634B (es)
SI (1) SI9110156B (es)
SK (1) SK280426B6 (es)
WO (1) WO1991011495A1 (es)
YU (1) YU49203B (es)
ZA (1) ZA91754B (es)

Families Citing this family (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5776434A (en) * 1988-12-06 1998-07-07 Riker Laboratories, Inc. Medicinal aerosol formulations
DE4003270A1 (de) 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
WO1992000062A1 (en) * 1990-06-27 1992-01-09 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
DE69105212T2 (de) * 1990-10-18 1995-03-23 Minnesota Mining & Mfg Aerosolzubereitung, die beclometason 17,21-dipropionat enthält.
MX9203481A (es) 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
GB9024366D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
HU205249B (en) * 1990-11-09 1992-04-28 Egyt Gyogyszervegyeszeti Gyar Process for producing suspensive aerosole composition
US5725791A (en) * 1991-03-28 1998-03-10 E. I. Du Pont De Nemours And Company Azeotropic and azeotrope-like compositions of 1,1,2,2-tetrafluoroethane
US5182040A (en) * 1991-03-28 1993-01-26 E. I. Du Pont De Nemours And Company Azeotropic and azeotrope-like compositions of 1,1,2,2-tetrafluoroethane
DE69231991T2 (de) 1991-06-10 2002-04-04 Schering Corp Fluorchlorkohlenwasserstofffreie Aerosolformulierungen
PT656207E (pt) * 1991-06-10 2001-11-30 Schering Corp Formulacoes de aerossois sem clorofluorocarbonetos
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
US5916540A (en) * 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
AU663905B2 (en) 1991-12-12 1995-10-26 Glaxo Group Limited Medicaments
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
ATE128350T1 (de) * 1991-12-12 1995-10-15 Glaxo Group Ltd Pharmazeutische aerosolformulierung.
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US20030103907A1 (en) * 1991-12-18 2003-06-05 Schultz Robert K. Suspension aerosol formulations
ATE150296T1 (de) * 1991-12-18 1997-04-15 Minnesota Mining & Mfg Aerosolzusammensetzungen für arzneimittelsuspensionen
DE4203306A1 (de) * 1992-02-06 1993-08-12 Ig Spruehtechnik Gmbh Asthma oder pulmonal-aerosolzubereitungen mit lecithin
AU4238393A (en) * 1992-05-04 1993-11-29 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
DE4218291A1 (de) * 1992-06-03 1993-12-09 Mattern Et Partner Pharmazeuti Dosierspray für pernasale Applikation
US5833950A (en) * 1992-07-31 1998-11-10 Glaxo Group Limited Aerosol formulations containing beclomethasone dipropionate-1, 1, 1, 2-tetrafluoroethane solvate
WO1994004629A1 (en) * 1992-08-21 1994-03-03 E.I. Du Pont De Nemours And Company Substantially constant boiling mixtures of 1,1,1,2-tetrafluoroethane, dimethyl ether and isobutane
KR100312357B1 (ko) * 1992-12-09 2002-04-24 데이비드 이. 프랭크하우저 안정화된약제의에어로졸용액제제
US5458798A (en) 1993-02-05 1995-10-17 E. I. Du Pont De Nemours And Company Azeotropic and azeotrope-like compositions of a hydrofluorocarbon and a hydrocarbon
US5474758A (en) * 1993-07-28 1995-12-12 Minnesota Mining And Manufacturing Company Seals for use in an aerosol delivery device
AU680967B2 (en) * 1993-12-20 1997-08-14 Minnesota Mining And Manufacturing Company Flunisolide aerosol formulations
CH686806A5 (de) * 1994-01-12 1996-06-28 Cerberus Ag Gasgemisch zur Funktionspruefung von Rauchmeldern.
US5417871A (en) * 1994-03-11 1995-05-23 E. I. Du Pont De Nemours And Company Hydrofluorocarbon compositions
US6001273A (en) 1994-03-11 1999-12-14 Minor; Barbara Haviland Binary azeotropes of difluoromethane and hydrocarbons
GB9419536D0 (en) * 1994-09-28 1994-11-16 Glaxo Inc Medicaments
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
CZ288146B6 (en) 1994-12-22 2001-05-16 Astra Ab Pharmaceutical aerosol preparation, process of its preparation and use
US6013245A (en) * 1995-01-26 2000-01-11 Glaxo Group Limited Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant
GB9507768D0 (en) 1995-04-13 1995-05-31 Glaxo Group Ltd Method of apparatus
US6054488A (en) * 1996-06-11 2000-04-25 3M Innovative Properties Company Medicinal aerosol formulations of formoterol
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
GB9620187D0 (en) * 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
AU718967B2 (en) 1997-02-05 2000-05-04 Jagotec Ag Medical aerosol formulations
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
GB9805938D0 (en) 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
US6264923B1 (en) 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
EP1100465B1 (de) 1998-07-24 2004-11-24 Jago Research Ag Medizinische aerosolformulierungen
US6475467B1 (en) 1998-08-04 2002-11-05 Jago Research Ag Medicinal aerosol formulations
US6458338B1 (en) * 1998-09-22 2002-10-01 Aeropharm Technology Incorporated Amino acid stabilized medicinal aerosol formulations
US7217409B2 (en) 2000-09-22 2007-05-15 Smithkline Beecham Corporation Alkanoic acid derivatives
US20020193392A1 (en) * 2000-11-13 2002-12-19 Christel Schmelzer Pharmaceutical compositions based on tiotropium salts of salts of salmeterol
KR100881258B1 (ko) 2000-12-22 2009-02-05 글락소 그룹 리미티드 살메테롤 지나포에이트를 위한 정량식 흡입기
US20110301569A1 (en) 2001-01-20 2011-12-08 Gordon Wayne Dyer Methods and apparatus for the CVCS
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US6919325B2 (en) 2001-09-14 2005-07-19 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US7217833B2 (en) 2002-02-13 2007-05-15 Glaxco Group Limited Carboxylic acid compounds for use as surfactants
GB0205327D0 (en) 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
US7754242B2 (en) * 2002-03-20 2010-07-13 Alkermes, Inc. Inhalable sustained therapeutic formulations
US7279451B2 (en) * 2002-10-25 2007-10-09 Honeywell International Inc. Compositions containing fluorine substituted olefins
US20040152720A1 (en) * 2002-12-20 2004-08-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powdered medicaments containing a tiotropium salt and salmeterol xinafoate
JP2006527237A (ja) 2003-06-13 2006-11-30 アルタナ　ファルマ　アクチエンゲゼルシャフト ホルモテロールと及びシクレソニドの組合せ物
EP1654312B1 (en) 2003-08-11 2014-01-15 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
JP5053635B2 (ja) 2003-08-29 2012-10-17 グラクソ グループ リミテッド 医療用定量噴霧式吸入器及びそれに関連する方法
US8371292B2 (en) 2003-09-16 2013-02-12 Nycomed Gmbh Use of ciclesonide for the treatment of respiratory diseases
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
EP1744800B1 (en) 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
EP2425820B1 (en) 2007-02-11 2015-04-08 MAP Pharmaceuticals Inc Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
WO2010076339A1 (en) 2009-01-05 2010-07-08 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Means and method for the treatment of antibody deficiency diseases based on il-21 and il-21 variants
JP2013512193A (ja) 2009-11-24 2013-04-11 ギリアード サイエンシーズ， インコーポレイテッド 慢性閉塞性肺疾患の処置のための吸入型ホスホマイシン／トブラマイシン
WO2011081937A1 (en) 2009-12-15 2011-07-07 Gilead Sciences, Inc. Corticosteroid-beta-agonist-muscarinic antagonist compounds for use in therapy
AR079451A1 (es) 2009-12-18 2012-01-25 Nycomed Gmbh Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina
US8367829B2 (en) 2010-05-10 2013-02-05 Gilead Sciences, Inc. Bi-functional pyrazolopyridine compounds
WO2011143105A1 (en) 2010-05-10 2011-11-17 Gilead Sciences, Inc. Bifunctional quinoline derivatives
AU2011260713A1 (en) 2010-06-04 2013-01-10 Trifoilium Aps Trefoil factors (TFF) for the treatment of chronic pulmonary diseases
CN103221039A (zh) 2010-09-09 2013-07-24 三叶草私人有限公司 血管生成抑制剂的气道给药
GB201108039D0 (en) 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions
EP2721036B1 (en) 2011-06-15 2015-07-22 Takeda GmbH Novel 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isoquinoline compounds
MX2013014888A (es) 2011-06-17 2014-02-27 Takeda Gmbh Novedosos derivados de ftalazinona-pirrolopirimidinacarboxamida.
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
GB201117621D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
GB201117619D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
EA032734B1 (ru) 2012-05-29 2019-07-31 Парион Сайэнс, Инк. Дендримероподобные аминоамиды, обладающие активностью блокаторов натриевых каналов, для лечения сухости глаз и других заболеваний слизистых оболочек
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
BR112015014178A2 (pt) 2012-12-17 2017-07-11 Parion Sciences Inc compostos de 3,5-diamino-6-cloro-n-(n-(4-fenilbutil)carbamimidoil) pirazina-2- carboxamida
RS55618B1 (sr) 2012-12-17 2017-06-30 Parion Sciences Inc Derivati hloropirazin karboksamida korisni za lečenje bolesti kojima pogoduje nedovoljna hidracija sluznica
GB201306984D0 (en) 2013-04-17 2013-05-29 Mexichem Amanco Holding Sa Composition
EP3383366B2 (en) 2015-12-04 2024-06-05 Mexichem Fluor S.A. de C.V. Pharmaceutical composition
CA3037080C (en) 2016-09-19 2021-05-18 Mexichem Fluor S.A. De C.V. Stable pharmaceutical compositions comprising indacaterol and 1,1-difluoroethane (hfa-152a) suitable for use in metered dose inhalers (mdis)
EP3515432B1 (en) 2016-09-19 2021-08-25 Mexichem Fluor S.A. de C.V. Pharmaceutical composition comprising glycopyrrolate
BR112019005168A2 (pt) 2016-09-19 2019-06-11 Mexichem Fluor Sa De Cv composição farmacêutica, recipiente vedado, inalador de dose medida, e, métodos para tratar um paciente que sofre ou susceptível de sofrer de um distúrbio respiratório, para melhoria da estabilidade de uma composição farmacêutica e do desempenho de aerossolização de uma composição farmacêutica e para reduzir o potencial de aquecimento global de uma composição farmacêutica
WO2018069210A1 (en) 2016-10-10 2018-04-19 Takeda Gmbh Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB902590A (en) 1960-03-22 1962-08-01 Allied Chem Production of heptafluoropropane
DE1542076A1 (de) * 1966-04-21 1970-03-26 Colgate Palmolive Co Aerosol-Treibmittel
MX3864E (es) 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona
US4405598A (en) 1976-01-30 1983-09-20 Fisons, Limited Composition for treating asthma
NL7708731A (nl) * 1976-08-13 1978-02-15 Montedison Spa Werkwijze voor de bereiding van nieuwe drijf- middelsamenstellingen voor aerosolen.
JPS5325284A (en) * 1976-08-19 1978-03-08 Daikin Ind Ltd Aerosol composition
US4352789A (en) 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
JPS5734174A (en) * 1980-08-11 1982-02-24 Toyo Aerosol Kogyo Kk Powdered aerosol composition
GB8613811D0 (en) * 1986-06-06 1986-07-09 Phares Pharm Res Nv Composition & method
GB8501015D0 (en) 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
US4778674A (en) * 1986-05-28 1988-10-18 Richardson-Vicks Inc. Dry aerosol foam
DE3784594T2 (de) 1986-08-11 1994-01-05 Innovata Biomed Ltd Mikrokapseln enthaltende pharmazeutische Zusammensetzungen.
DE3815480A1 (de) 1988-05-06 1989-11-16 Boehringer Ingelheim Kg Synergistische kombinationen und ihre verwendung als therapeutika
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE3905726A1 (de) * 1989-02-24 1990-08-30 Hoechst Ag Druckgaspackung und treibmittel fuer aerosole
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
MX9203481A (es) * 1990-10-18 1992-07-01 Minnesota Mining & Mfg Formulaciones.
US5190029A (en) * 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US6013245A (en) * 1995-01-26 2000-01-11 Glaxo Group Limited Aerosol formulation containing beclomethasone dipropionate and 1,1,1,2,3,3,3-heptafluoro-n-propane as propellant
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
US6004537A (en) * 1998-12-18 1999-12-21 Baker Norton Pharmaceuticals, Inc. Pharmaceutical solution aerosol formulations containing fluoroalkanes, budesonide and formoterol

Also Published As

Publication number Publication date
NO923039L (no) 1992-07-31
CZ286691B6 (cs) 2000-06-14
IE910350A1 (en) 1991-08-14
DE59108979D1 (de) 1998-06-10
PT96634B (pt) 1998-07-31
ZA91754B (en) 1992-10-28
SK280426B6 (sk) 2000-02-14
YU15691A (sh) 1994-01-20
NZ236973A (en) 1993-08-26
HK1010786A1 (en) 1999-06-25
CS26491A3 (en) 1991-09-15
EP0514415A1 (de) 1992-11-25
DK0514415T3 (da) 1998-10-07
JPH05504160A (ja) 1993-07-01
HRP940735B1 (en) 1999-10-31
HU9202509D0 (en) 1992-10-28
HU218784B (hu) 2000-12-28
SI9110156B (sl) 1999-04-30
FI923490A0 (fi) 1992-08-03
NO923039D0 (no) 1992-07-31
CA2075058A1 (en) 1991-08-04
FI923490A (fi) 1992-08-03
IE910351A1 (en) 1991-08-14
AU7211391A (en) 1991-08-21
PT96634A (pt) 1991-10-31
AU650001B2 (en) 1994-06-09
NO302419B1 (no) 1998-03-02
FI102905B1 (fi) 1999-03-15
ATE165863T1 (de) 1998-05-15
FI102905B (fi) 1999-03-15
IL97028A0 (en) 1992-03-29
DE4003272A1 (de) 1991-08-08
YU49203B (sh) 2004-09-03
HUT62456A (en) 1993-05-28
US6413497B1 (en) 2002-07-02
SI9110156A (sl) 1998-04-30
WO1991011495A1 (de) 1991-08-08
EP0514415B1 (de) 1998-05-06
IL97028A (en) 1994-08-26
CA2075058C (en) 2001-03-27
HRP940735A2 (en) 1997-06-30
JP3497161B2 (ja) 2004-02-16

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