US5595886A
(en)
|
1986-01-27 |
1997-01-21 |
Chiron Corporation |
Protein complexes having Factor VIII:C activity and production thereof
|
US6048729A
(en)
|
1987-05-01 |
2000-04-11 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
US6544771B1
(en)
|
1987-12-11 |
2003-04-08 |
Cell Genesys, Inc. |
Retroviral gene therapy vectors and therapeutic methods based thereon
|
WO1993000103A1
(en)
*
|
1991-06-21 |
1993-01-07 |
The Wistar Institute Of Anatomy And Biology |
Chimeric envelope proteins for viral targeting
|
DE69232890T2
(de)
*
|
1991-10-04 |
2003-10-09 |
Whitehead Biomedical Inst |
Regulierung der systemischen immunantworten mittels zytokinen und antigenen
|
US5637483A
(en)
*
|
1991-10-04 |
1997-06-10 |
Whitehead Institute For Biomedical Research |
Irradiated tumor cell vaccine engineered to express GM-CSF
|
US5904920A
(en)
*
|
1991-10-04 |
1999-05-18 |
Whitehead Institute For Biomedical Research |
Regulation of systemic immune responses utilizing cytokines and antigens
|
US6692737B1
(en)
|
1991-11-05 |
2004-02-17 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
US6054288A
(en)
*
|
1991-11-05 |
2000-04-25 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
PT101031B
(pt)
|
1991-11-05 |
2002-07-31 |
Transkaryotic Therapies Inc |
Processo para o fornecimento de proteinas por terapia genetica
|
US6063630A
(en)
|
1991-11-05 |
2000-05-16 |
Transkaryotic Therapies, Inc. |
Targeted introduction of DNA into primary or secondary cells and their use for gene therapy
|
EP0646010A4
(en)
*
|
1992-06-19 |
1997-04-23 |
Gen Hospital Corp |
USE OF MÜLLSCHCHER INHIBITING SUBSTANCE FOR TREATING TUMORS AND FOR MODULATING THE EXPRESSION OF CLASS 1 MAIN HISTOCOMPATIBILITY ANTIQUES.
|
US5911983A
(en)
*
|
1992-06-26 |
1999-06-15 |
University Of Pittsburgh |
Gene therapy for Gaucher disease using retroviral vectors
|
US6531124B1
(en)
|
1992-07-10 |
2003-03-11 |
Transkaryotic Therapies, Inc. |
In vivo production and delivery of insulinotropin for gene therapy
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
GB9222931D0
(en)
*
|
1992-11-02 |
1992-12-16 |
Sandoz Ltd |
Organic compounds
|
US5830461A
(en)
*
|
1992-11-25 |
1998-11-03 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Methods for promoting wound healing and treating transplant-associated vasculopathy
|
US5658565A
(en)
*
|
1994-06-24 |
1997-08-19 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Inducible nitric oxide synthase gene for treatment of disease
|
EP0701563A4
(en)
*
|
1993-03-08 |
1997-07-02 |
Univ Pittsburgh |
GENE TRANSFER FOR THE TREATMENT OF CONNECTIVE TISSUES IN A HOST MAMMAL
|
FR2704236B1
(fr)
*
|
1993-04-21 |
1995-06-23 |
Pasteur Institut |
Vecteur rétroviral pour la préparation de cellules recombinantes susceptibles d'être implantées in vivo dans un but thérapeutique.
|
US5906817A
(en)
|
1993-04-21 |
1999-05-25 |
Institut Pasteur |
Biocompatible implant for the expression and in vivo secretion of a therapeutic substance
|
US5591625A
(en)
*
|
1993-11-24 |
1997-01-07 |
Case Western Reserve University |
Transduced mesenchymal stem cells
|
CA2155929A1
(en)
*
|
1993-12-14 |
1995-06-22 |
Christopher H. Evans |
Systemic gene treatment of connective tissue diseases
|
DE4411402A1
(de)
*
|
1994-03-31 |
1995-10-05 |
Juergen Schrader |
DNA-Expressionsvektoren zur Verwendung in der gentherapeutischen Behandlung von Gefäßerkrankungen
|
AU694222B2
(en)
|
1994-05-02 |
1998-07-16 |
Bernd Groner |
Bifunctional protein, preparation and use
|
JP4303315B2
(ja)
*
|
1994-05-09 |
2009-07-29 |
オックスフォード バイオメディカ(ユーケー)リミテッド |
非交差性レトロウイルスベクター
|
US6013517A
(en)
*
|
1994-05-09 |
2000-01-11 |
Chiron Corporation |
Crossless retroviral vectors
|
US6150137A
(en)
|
1994-05-27 |
2000-11-21 |
Ariad Pharmaceuticals, Inc. |
Immunosuppressant target proteins
|
EP0781333A1
(en)
*
|
1994-08-26 |
1997-07-02 |
Novartis AG (Novartis SA) (Novartis Inc.) |
Gene therapy for transplantation and inflammatory or thrombotic conditions
|
FR2726005B1
(fr)
*
|
1994-10-10 |
1997-01-03 |
Adim |
Lignees immortalisees de cellules endotheliales cerebrales et leurs applications au traitement de differents troubles ou maladies primaires et secondaires neurologiques ou psychiatriques
|
US6818439B1
(en)
|
1994-12-30 |
2004-11-16 |
Chiron Corporation |
Methods for administration of recombinant gene delivery vehicles for treatment of hemophilia and other disorders
|
CA2228378A1
(en)
*
|
1995-07-31 |
1997-02-13 |
Centre De Recherche De L'hopital Sainte-Justine |
Cytidine deaminase cdna as a positive selectable marker for gene transfer, gene therapy and protein synthesis
|
FR2737731B1
(fr)
|
1995-08-07 |
1997-10-10 |
Pasteur Institut |
Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote
|
WO1997018319A1
(en)
*
|
1995-11-14 |
1997-05-22 |
Somatix Therapy Corporation |
Joint expression of gtp cyclohydrolase and tyrosine hydroxylase
|
US5837464A
(en)
*
|
1996-01-29 |
1998-11-17 |
Virologic, Inc. |
Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
|
US6242187B1
(en)
|
1996-01-29 |
2001-06-05 |
Virologic, Inc. |
Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
|
US6689757B1
(en)
|
1996-02-12 |
2004-02-10 |
M.L. Laboratories Plc |
Methods for vaccination and vaccines therefor
|
AU1873097A
(en)
*
|
1996-02-14 |
1997-09-02 |
New England Deaconess Hospital Corporation |
Gene therapy of entothelial cells with anti-apoptotic proteins for transplantation and inflammatory conditions
|
US5965126A
(en)
*
|
1996-03-25 |
1999-10-12 |
The Penn State Research Foundation |
use of mutant alkyltransferases for gene therapy to protect from toxicity of therapeutic alkylating agents
|
US6723531B2
(en)
|
1996-04-05 |
2004-04-20 |
The Salk Institute For Biological Studies |
Method for modulating expression of exogenous genes in mammalian systems, and products related thereto
|
AUPN970196A0
(en)
*
|
1996-05-06 |
1996-05-30 |
Unisearch Limited |
A long-term and high expression, single gene retroviral vector with applications to progenitor and mature haematopoietic cells
|
US6027721A
(en)
*
|
1996-05-20 |
2000-02-22 |
Cytotherapeutics, Inc. |
Device and method for encapsulated gene therapy
|
WO1997045533A1
(en)
*
|
1996-05-28 |
1997-12-04 |
The Regents Of The University Of Michigan |
Engineering oral tissues
|
US6001816A
(en)
*
|
1996-06-20 |
1999-12-14 |
Merck & Co., Inc. |
Gene therapy for leptin deficiency
|
EP0954579A1
(en)
*
|
1996-06-20 |
1999-11-10 |
Merck & Co., Inc. |
Gene therapy for obesity
|
AU4401297A
(en)
*
|
1996-09-21 |
1998-04-14 |
Viromedica Pacific Limited |
Improved retroviral vectors for gene therapy
|
US5980887A
(en)
*
|
1996-11-08 |
1999-11-09 |
St. Elizabeth's Medical Center Of Boston |
Methods for enhancing angiogenesis with endothelial progenitor cells
|
US5833651A
(en)
*
|
1996-11-08 |
1998-11-10 |
Medtronic, Inc. |
Therapeutic intraluminal stents
|
US8075880B2
(en)
|
1999-01-11 |
2011-12-13 |
Steward St. Elizabeth's Medical Center Of Boston, Inc. |
Compositions and methods for regulating angiogenesis
|
WO1998042854A1
(en)
*
|
1997-03-27 |
1998-10-01 |
The Board Of Trustees Of The Leland Stanford Junior University |
Functional genomic screen for rna regulatory sequences and interacting molecules
|
US6300488B1
(en)
|
1997-07-10 |
2001-10-09 |
The Salk Institute For Biological Studies |
Modified lepidopteran receptors and hybrid multifunctional proteins for use in transcription and regulation of transgene expression
|
CA2308511C
(en)
|
1997-10-29 |
2016-01-19 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Use of transfected or transduced mammalian cells for treating bone pathologies
|
CA2305787A1
(en)
|
2000-05-09 |
2001-11-09 |
The University Of British Columbia |
Cxcr4 antagonist treatment of hematopoietic cells
|
CA2245224A1
(en)
|
1998-08-14 |
2000-02-14 |
Jiang-Hong Giong |
Chemokine receptor antagonists and chemotherapeutics
|
AU762472B2
(en)
|
1998-03-13 |
2003-06-26 |
University Of British Columbia, The |
Therapeutic chemokine receptor antagonists
|
US6743631B1
(en)
|
1998-03-17 |
2004-06-01 |
North Shore University Hospital Research Corporation |
Use of human serum resistant vector particles and cell lines for human gene therapy
|
US6841537B1
(en)
|
1998-04-22 |
2005-01-11 |
Protiva Biotherapeutics Inc. |
Combination therapy using nucleic acids and conventional drugs
|
US6841538B1
(en)
|
1998-04-22 |
2005-01-11 |
Inex Pharmaceuticals Corporation |
Combination therapy using nucleic acids and radio therapy
|
DE19822115B4
(de)
*
|
1998-05-08 |
2004-04-08 |
Heinrich-Pette-Institut |
Retrovirale Gentransfervektoren
|
US6333318B1
(en)
|
1998-05-14 |
2001-12-25 |
The Salk Institute For Biological Studies |
Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto
|
WO1999059622A1
(en)
*
|
1998-05-20 |
1999-11-25 |
Genentech, Inc. |
Treatment for hemophilia
|
WO1999061598A2
(en)
*
|
1998-05-26 |
1999-12-02 |
University Of Florida |
Lentiviral vector compositions and methods of use
|
US6319905B1
(en)
|
1998-12-29 |
2001-11-20 |
Cell Genesys, Inc. |
Method of controlling L-Dopa production and of treating dopamine deficiency
|
DE19956568A1
(de)
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
AU767066B2
(en)
|
1999-03-03 |
2003-10-30 |
Curis, Inc. |
Methods of modulating lipid metabolism and storage
|
IL145055A0
(en)
|
1999-03-12 |
2002-06-30 |
Gpc Biotech Inc |
Methods and reagents for identifying synthetic genetic elements
|
US7396905B1
(en)
|
1999-05-21 |
2008-07-08 |
Mckeon Frank |
Calcipressins: endogenous inhibitors of calcineurin, uses and reagents related thereto
|
US7504253B2
(en)
|
1999-06-11 |
2009-03-17 |
The Burnham Institute For Medical Research |
Nucleic acid encoding proteins involved in protein degradation, products and methods related thereof
|
US7057015B1
(en)
|
1999-10-20 |
2006-06-06 |
The Salk Institute For Biological Studies |
Hormone receptor functional dimers and methods of their use
|
DE10100586C1
(de)
|
2001-01-09 |
2002-04-11 |
Ribopharma Ag |
Verfahren zur Hemmung der Expression eines Ziegens
|
US6951839B1
(en)
|
1999-11-30 |
2005-10-04 |
Curis, Inc. |
Methods and compositions for regulating lymphocyte activity
|
US8168178B2
(en)
|
1999-11-30 |
2012-05-01 |
Curis, Inc. |
Methods and compositions for regulating lymphocyte activity
|
GB9930616D0
(en)
|
1999-12-24 |
2000-02-16 |
Mathilda & Terence Kennedy Ins |
Activation and inhibition of the immune system
|
JP2003518942A
(ja)
|
1999-12-30 |
2003-06-17 |
プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ |
肝細胞成長、形質細胞分化、又はt細胞サブセットの活性を、xbp−1活性の変調により変調することに関する方法及び組成物
|
US20010053769A1
(en)
|
2000-01-21 |
2001-12-20 |
Christiane Ferran |
Use of pro-apoptotic factors in treatment of atherosclerosis
|
US7368425B2
(en)
|
2006-03-24 |
2008-05-06 |
Chemokine Therapeutics Corp. |
Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis
|
US20050059584A1
(en)
|
2002-08-16 |
2005-03-17 |
Ahmed Merzouk |
Novel chemokine mimetics synthesis and their use
|
US7378098B2
(en)
|
2000-04-12 |
2008-05-27 |
The University Of British Columbia |
CXC chemokine receptor 4 agonist peptides
|
JP2004503216A
(ja)
|
2000-05-22 |
2004-02-05 |
ジョンズ・ホプキンス・ユニバーシティ |
疾患を阻止するための血管移植片の遺伝子工学処理
|
JP2004522432A
(ja)
|
2000-12-22 |
2004-07-29 |
シノヴィス・リミテッド |
Toll関連レセプター(trr)シグナル伝達の調節方法
|
US7423142B2
(en)
|
2001-01-09 |
2008-09-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
US7767802B2
(en)
|
2001-01-09 |
2010-08-03 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of anti-apoptotic genes
|
EP1900815B1
(en)
|
2001-07-12 |
2016-09-07 |
University of Massachusetts |
In vivo production of small interfering RNAs that mediate gene silencing
|
CA2453183C
(en)
|
2001-07-12 |
2016-05-10 |
University Of Massachusetts |
In vivo production of small interfering rnas that mediate gene silencing
|
US7745418B2
(en)
|
2001-10-12 |
2010-06-29 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting viral replication
|
IL152904A0
(en)
|
2002-01-24 |
2003-06-24 |
Gamida Cell Ltd |
Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
|
CA2421269A1
(en)
|
2002-08-09 |
2004-02-09 |
President And Fellows Of Harvard College |
Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
|
US7470538B2
(en)
|
2002-12-05 |
2008-12-30 |
Case Western Reserve University |
Cell-based therapies for ischemia
|
EP1594433B8
(en)
|
2003-01-14 |
2016-12-21 |
Dana-Farber Cancer Institute, Inc. |
Cancer therapy sensitizer
|
DK1624936T3
(da)
|
2003-05-16 |
2010-03-15 |
Univ Laval |
CNS-chloridmodulering og anvendelser deraf
|
ES2864206T3
(es)
|
2003-06-02 |
2021-10-13 |
Univ Massachusetts |
Métodos y composiciones para mejorar la eficacia y la especificidad del ARNi
|
ES2712695T3
(es)
|
2003-06-02 |
2019-05-14 |
Univ Massachusetts |
Métodos y composiciones para controlar la eficacia de la silenciación del ARN
|
DK1677735T3
(da)
|
2003-10-17 |
2014-10-27 |
Joslin Diabetes Center Inc |
Fremgangsmåder og sammensætninger til modulering af adipocytfunktion
|
EP1735009A4
(en)
|
2004-03-12 |
2011-03-30 |
Alnylam Pharmaceuticals Inc |
RNAI AGENTS TARGETING THE VASCULAR ENDOTHELIUM GROWTH FACTOR (VEGF)
|
CA2563329C
(en)
*
|
2004-04-30 |
2016-01-26 |
Orbus Medical Technologies, Inc. |
Medical device with coating for capturing genetically-altered cells and methods for using same
|
CA2571243A1
(en)
|
2004-06-21 |
2006-01-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
|
WO2006017673A2
(en)
|
2004-08-03 |
2006-02-16 |
Biogen Idec Ma Inc. |
Taj in neuronal function
|
EP1859277A4
(en)
|
2005-02-17 |
2010-03-17 |
Biogen Idec Inc |
TREATMENT OF NEUROLOGICAL DISORDERS
|
US8889844B2
(en)
|
2005-08-16 |
2014-11-18 |
Takara Bio Inc. |
Nucleic acid for treatment or prevention of immunodeficiency virus infection
|
EP1762609B1
(en)
|
2005-09-13 |
2012-04-04 |
Takara Bio Inc. |
Serum-free medium for the production of retroviral vectors
|
CA2626584A1
(en)
|
2005-11-04 |
2007-05-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of nav1.8 gene
|
CA2626690A1
(en)
|
2005-11-09 |
2007-05-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of factor v leiden mutant gene
|
AU2006315562C1
(en)
|
2005-11-12 |
2013-10-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for treating depression using NCAM peptide mimetics
|
RS54111B1
(en)
|
2005-11-18 |
2015-12-31 |
Glenmark Pharmaceuticals S.A. |
ANTI-ALPHA 2 INTEGRIN ANTIBODIES AND THEIR USES
|
CA2524619A1
(en)
|
2005-11-22 |
2007-05-22 |
Ottawa Health Research Institute |
Novel stem cells, nucleotide sequences and proteins therefrom
|
US8846393B2
(en)
|
2005-11-29 |
2014-09-30 |
Gamida-Cell Ltd. |
Methods of improving stem cell homing and engraftment
|
ES2544861T3
(es)
|
2006-03-31 |
2015-09-04 |
Alnylam Pharmaceuticals Inc. |
Composiciones y métodos para inhibir la expresión del gen Eg5
|
US7691824B2
(en)
|
2006-04-28 |
2010-04-06 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a gene from the JC virus
|
NZ572666A
(en)
|
2006-05-11 |
2010-11-26 |
Alnylam Pharmaceuticals Inc |
Compositions comprising double stranded rna and methods for inhibiting expression of the pcsk9 gene
|
WO2007137156A2
(en)
|
2006-05-19 |
2007-11-29 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of aha and therapeutic uses thereof
|
US7888498B2
(en)
|
2006-05-22 |
2011-02-15 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of IKK-B gene
|
JP5496658B2
(ja)
|
2006-05-25 |
2014-05-21 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
脳卒中を処置する方法
|
US8598333B2
(en)
|
2006-05-26 |
2013-12-03 |
Alnylam Pharmaceuticals, Inc. |
SiRNA silencing of genes expressed in cancer
|
EP2111553B1
(en)
|
2007-01-24 |
2018-09-19 |
Carnegie Mellon University |
Optical biosensors
|
CN106890342B
(zh)
|
2007-02-06 |
2022-09-23 |
俞泰俊 |
使用基因疗法治疗和预防神经变性疾病
|
PE20090064A1
(es)
|
2007-03-26 |
2009-03-02 |
Novartis Ag |
Acido ribonucleico de doble cadena para inhibir la expresion del gen e6ap humano y composicion farmaceutica que lo comprende
|
EP2138580B1
(en)
|
2007-04-20 |
2013-03-20 |
Takara Bio, Inc. |
Vector for gene therapy
|
CN101688206B
(zh)
|
2007-07-05 |
2013-05-15 |
诺瓦提斯公司 |
用于治疗病毒感染的dsRNA
|
EP2617828B1
(en)
|
2007-12-10 |
2014-09-24 |
Alnylam Pharmaceuticals Inc. |
Compositions and methods for inhibiting expression of factor VII gene
|
JP5697027B2
(ja)
|
2008-02-15 |
2015-04-08 |
タフツ ユニバーシティー |
マウス網膜上への細胞膜傷害複合体(mac)生成のヒト化モデル、並びに、黄斑変性の処置のための組成物とキットと方法
|
US8877896B2
(en)
|
2008-02-15 |
2014-11-04 |
Tufts University |
Compositions, methods and kits for modeling, diagnosing, and treating complement disorders
|
AU2009221775B2
(en)
|
2008-03-05 |
2015-05-07 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of Eg5 and VEGF genes
|
CA2725208A1
(en)
|
2008-05-06 |
2009-11-12 |
Joslin Diabetes Center, Inc. |
Methods and compositions for inducing brown adipogenesis
|
EP3208337A1
(en)
|
2008-09-02 |
2017-08-23 |
Alnylam Pharmaceuticals, Inc. |
Compositions for combined inhibition of mutant egfr and il-6 expression
|
EP3584320A1
(en)
|
2008-09-25 |
2019-12-25 |
Alnylam Pharmaceuticals, Inc. |
Lipid formulated compositions and methods for inhibiting expression of serum amyloid a gene
|
CN106834291B
(zh)
|
2008-10-20 |
2020-09-29 |
阿尔尼拉姆医药品有限公司 |
抑制运甲状腺素蛋白表达的组合物和方法
|
KR20110094029A
(ko)
|
2008-11-10 |
2011-08-19 |
알렉시온 파마슈티칼스, 인코포레이티드 |
보체-관련된 장애를 치료하는 방법 및 조성물
|
AU2009324534B2
(en)
|
2008-12-10 |
2015-07-30 |
Alnylam Pharmaceuticals, Inc. |
GNAQ targeted dsRNA compositions and methods for inhibiting expression
|
JP2009148273A
(ja)
*
|
2009-01-21 |
2009-07-09 |
Ichikazu Nakao |
内皮細胞を分化増殖させる方法
|
EP2752427A1
(en)
|
2009-02-24 |
2014-07-09 |
Alexion Pharmaceuticals, Inc. |
Antibodies containing therapeutic TPO/EPO mimetic peptides
|
US20120041051A1
(en)
|
2009-02-26 |
2012-02-16 |
Kevin Fitzgerald |
Compositions And Methods For Inhibiting Expression Of MIG-12 Gene
|
WO2010105209A1
(en)
|
2009-03-12 |
2010-09-16 |
Alnylam Pharmaceuticals, Inc. |
LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES
|
KR101764437B1
(ko)
|
2009-03-20 |
2017-08-02 |
메소블라스트, 아이엔씨. |
재프로그램된 다분화능 세포의 생성 방법
|
US9149024B2
(en)
|
2009-06-22 |
2015-10-06 |
Massachusetts Eye & Ear Infirmary |
Islet1 (Isl1) and hearing loss
|
WO2011024791A1
(ja)
|
2009-08-25 |
2011-03-03 |
タカラバイオ株式会社 |
レチノイン酸存在下でのt細胞集団の製造方法
|
WO2011050210A1
(en)
|
2009-10-21 |
2011-04-28 |
Agios Pharmaceuticals, Inc. |
Methods and compositions for cell-proliferation-related disorders
|
US9745589B2
(en)
|
2010-01-14 |
2017-08-29 |
Cornell University |
Methods for modulating skeletal remodeling and patterning by modulating SHN2 activity, SHN3 activity, or SHN2 and SHN3 activity in combination
|
JP5860029B2
(ja)
|
2010-03-29 |
2016-02-16 |
アルナイラム ファーマシューティカルズ, インコーポレイテッドAlnylam Pharmaceuticals, Inc. |
トランスチレチン(TTR)関連眼アミロイドーシスのためのsiRNA療法
|
ES2623799T3
(es)
|
2010-04-30 |
2017-07-12 |
Alexion Pharmaceuticals, Inc. |
Anticuerpos anti-C5a y métodos para el uso de los anticuerpos
|
WO2012021891A2
(en)
|
2010-08-13 |
2012-02-16 |
Tufts University |
Compositions, kits and methods for treatment of complement-related disorders
|
EP2612909B1
(en)
|
2010-10-05 |
2015-02-25 |
Takara Bio, Inc. |
Method for producing virus vector
|
WO2012051301A1
(en)
|
2010-10-12 |
2012-04-19 |
President And Fellows Of Harvard College |
Methods for identifying modulators of triglyceride metabolism, for modulating triglyceride metabolism and for identifying subjects at risk for abnormal triglyceride metabolism
|
US8815942B2
(en)
|
2010-10-20 |
2014-08-26 |
The Royal Institution For The Advancement Of Learning/Mcgill University |
Combination therapy and uses thereof for treatment and prevention of parasitic infection and disease
|
US9958458B2
(en)
|
2010-12-27 |
2018-05-01 |
Brown University |
Therapeutic and diagnostic methods involving biglycan and utrophin
|
WO2012109238A2
(en)
|
2011-02-07 |
2012-08-16 |
President And Fellows Of Harvard College |
Methods for increasing immune responses using agents that directly bind to and activate ire-1
|
EP2723351B1
(en)
|
2011-06-21 |
2018-02-14 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibition of expression of protein c (proc) genes
|
MX344807B
(es)
|
2011-06-21 |
2017-01-09 |
Alnylam Pharmaceuticals Inc |
Composiciones y metodos para inhibicion de genes para alipoproteina c-iii (apoc3).
|
CA2848765A1
(en)
|
2011-09-15 |
2013-03-21 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Immunotherapy and diagnosis of mucormycosis using coth
|
SG11201404608WA
(en)
|
2012-02-13 |
2014-09-26 |
Gamida Cell Ltd |
Mesenchymal stem cells conditioned medium and methods of generating and using the same
|
JP6014119B2
(ja)
|
2012-03-22 |
2016-10-25 |
タカラバイオ株式会社 |
ウイルスベクターの製造方法
|
US9175266B2
(en)
|
2012-07-23 |
2015-11-03 |
Gamida Cell Ltd. |
Enhancement of natural killer (NK) cell proliferation and activity
|
US9567569B2
(en)
|
2012-07-23 |
2017-02-14 |
Gamida Cell Ltd. |
Methods of culturing and expanding mesenchymal stem cells
|
US20140120116A1
(en)
|
2012-10-26 |
2014-05-01 |
The Chinese University Of Hong Kong |
Treatment of cancer using smad3 inhibitor
|
US9856474B2
(en)
|
2013-01-16 |
2018-01-02 |
Iowa State University Research Foundation, Inc. |
Deep intronic target for splicing correction on spinal muscular atrophy gene
|
EP2769732A1
(en)
|
2013-02-22 |
2014-08-27 |
Sanofi |
Serpins: methods of therapeutic beta-cell regeneration and function
|
WO2014128257A1
(en)
|
2013-02-22 |
2014-08-28 |
Sanofi |
Serpins: methods of therapeutic beta-cell regeneration and function
|
EP2851086A1
(en)
|
2013-09-20 |
2015-03-25 |
Sanofi |
Serpins: methods of therapeutic ß-cell regeneration and function
|
JP6431035B2
(ja)
|
2013-03-13 |
2018-11-28 |
ジーンウィーブ バイオサイエンシズ,インコーポレイティド |
非複製的形質導入粒子及び形質導入粒子に基づくレポーターシステム
|
US9750823B2
(en)
|
2013-06-04 |
2017-09-05 |
Virginia Commonwealth University |
Use of a truncated CCN1 promoter for cancer diagnostics, therapeutics and theranostics
|
WO2014197586A1
(en)
|
2013-06-04 |
2014-12-11 |
Virginia Commonwealth University |
Mda-9/syntenin promoter to image and treat metastatic cancer cells
|
EP3004357A4
(en)
|
2013-06-04 |
2017-01-11 |
The Johns Hopkins University |
Peg-prom mediated surface expression of avidin/streptavidin
|
WO2014197535A1
(en)
|
2013-06-04 |
2014-12-11 |
Virginia Commonwealth University |
Recombinant cancer therapeutic cytokine
|
EP3003393A4
(en)
|
2013-06-04 |
2017-01-11 |
The Johns Hopkins University |
Tripartite cancer theranostic nucleic acid constructs
|
EP3521431A1
(en)
|
2013-09-25 |
2019-08-07 |
Cornell University |
Compounds for inducing anti-tumor immunity and methods thereof
|
NZ711451A
(en)
|
2014-03-07 |
2016-05-27 |
Alexion Pharma Inc |
Anti-c5 antibodies having improved pharmacokinetics
|
HUE052781T2
(hu)
|
2014-07-24 |
2021-05-28 |
Massachusetts Eye & Ear Infirmary |
RPGR génterápia a retinitis pigmentosa terápiájára
|
EP3892291A1
(en)
|
2014-08-28 |
2021-10-13 |
Tufts University |
Compositions, methods and kits for treating complement related disorders
|
WO2016118832A1
(en)
|
2015-01-22 |
2016-07-28 |
University Of Massachusetts |
Cancer immunotherapy
|
US20180215801A1
(en)
|
2015-01-29 |
2018-08-02 |
Board Of Trustees Of Michigan State University |
Cryptic polypeptides and uses thereof
|
LT3265568T
(lt)
|
2015-03-06 |
2020-08-25 |
Massachusetts Eye & Ear Infirmary |
Genų augmentacijos terapijos, skirtos paveldimai tinklainės degeneracijai, sukeltai prpf31 geno mutacijos
|
EP3735982A1
(en)
|
2015-03-10 |
2020-11-11 |
The University of Massachusetts |
Targeting gdf6 and bmp signaling for anti-melanoma therapy
|
WO2016183183A1
(en)
|
2015-05-11 |
2016-11-17 |
The Johns Hopkins University |
Autoimmune antibodies for use in inhibiting cancer cell growth
|
WO2016183585A1
(en)
|
2015-05-14 |
2016-11-17 |
Joslin Diabetes Center, Inc. |
Retinol-binding protein 3 (rbp3) as a protective factor in non-diabetic retinal degeneration
|
US9920100B2
(en)
|
2015-06-05 |
2018-03-20 |
The Chinese University Of Hong Kong |
Mimotopes of tropomyosin for use in immunotherapy for shellfish and/or arthropod allergy
|
WO2017066712A2
(en)
|
2015-10-16 |
2017-04-20 |
The Children's Medical Center Corporation |
Modulators of telomere disease
|
WO2017066796A2
(en)
|
2015-10-16 |
2017-04-20 |
The Children's Medical Center Corporation |
Modulators of telomere disease
|
WO2017087708A1
(en)
|
2015-11-19 |
2017-05-26 |
The Brigham And Women's Hospital, Inc. |
Lymphocyte antigen cd5-like (cd5l)-interleukin 12b (p40) heterodimers in immunity
|
WO2017117218A1
(en)
|
2015-12-30 |
2017-07-06 |
Momenta Pharmaceuticals, Inc. |
Methods related to biologics
|
EP3299460A1
(en)
|
2016-09-26 |
2018-03-28 |
Johann Wolfgang Goethe-Universität Frankfurt am Main |
Novel compounds and methods for modulating ubiquitination
|
US11459568B2
(en)
|
2016-10-31 |
2022-10-04 |
University Of Massachusetts |
Targeting microRNA-101-3p in cancer therapy
|
WO2018191599A1
(en)
|
2017-04-14 |
2018-10-18 |
University Of Massachusetts |
Brown fat-selective adipokines
|
CN110832072B
(zh)
|
2017-04-21 |
2023-11-07 |
真基因太科公司 |
用于生产非复制型腺病毒的细胞系以及制备所述细胞系的方法
|
EA202090149A1
(ru)
|
2017-06-28 |
2020-05-31 |
Ридженерон Фармасьютикалз, Инк. |
Антигенсвязывающие белки против вируса папилломы человека (hpv) и способы их применения
|
GB201710973D0
(en)
|
2017-07-07 |
2017-08-23 |
Avacta Life Sciences Ltd |
Scaffold proteins
|
EP3658184B1
(en)
|
2017-07-27 |
2023-09-06 |
Alexion Pharmaceuticals, Inc. |
High concentration anti-c5 antibody formulations
|
US11008602B2
(en)
|
2017-12-20 |
2021-05-18 |
Roche Molecular Systems, Inc. |
Non-replicative transduction particles and transduction particle-based reporter systems
|
IL276641B2
(en)
|
2018-02-12 |
2024-04-01 |
Tufts College |
CD59 to inhibit inflammasome activation
|
AU2019276372A1
(en)
|
2018-06-01 |
2020-12-24 |
Evotec International Gmbh |
Combination therapy for treating hepatitis B virus infection
|
EA202190315A1
(ru)
|
2018-07-19 |
2021-04-16 |
Ридженерон Фармасьютикалз, Инк. |
Химерные антигенные рецепторы со специфичностью к bcma и их применение
|
EA202191107A1
(ru)
|
2018-10-23 |
2021-09-17 |
Ридженерон Фармасьютикалз, Инк. |
T-клеточные рецепторы ny-eso-1 и способы их применения
|
US11325978B2
(en)
|
2018-11-06 |
2022-05-10 |
The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Compositions and methods for treating beta-globinopathies
|
WO2020120649A1
(en)
|
2018-12-13 |
2020-06-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Artificial antigen presenting cells that constitutively express an antigen along with a hla-class ii molecule
|
CN113227404A
(zh)
|
2018-12-27 |
2021-08-06 |
豪夫迈·罗氏有限公司 |
用于检测鲍氏不动杆菌的非复制型转导颗粒和基于转导颗粒的报告系统
|
US11572595B2
(en)
|
2018-12-31 |
2023-02-07 |
Roche Molecular Systems, Inc. |
Non-replicative transduction particles with one or more non-native tail fibers and transduction particle-based reporter systems
|
IT201900007060A1
(it)
|
2019-05-21 |
2020-11-21 |
St Superiore Di Sanita |
Cellule tumorali ingegnerizzate e loro usi
|
IT201900012540A1
(it)
|
2019-07-22 |
2021-01-22 |
Humanitas Mirasole Spa |
Inibitori di CHI3L1 e loro usi
|
CA3147903A1
(en)
|
2019-07-24 |
2021-01-28 |
Regeneron Pharmaceuticals, Inc. |
Chimeric antigen receptors with mage-a4 specificity and uses thereof
|
TW202120551A
(zh)
|
2019-08-12 |
2021-06-01 |
美商普瑞諾生物科技公司 |
藉由adcc靶向cd39表現細胞促進及增強t細胞介導免疫反應之方法及組合物
|
WO2021067526A1
(en)
|
2019-10-02 |
2021-04-08 |
Alexion Pharmaceuticals, Inc. |
Complement inhibitors for treating drug-induced complement-mediated response
|
WO2021074695A1
(en)
|
2019-10-16 |
2021-04-22 |
Avacta Life Sciences Limited |
PD-L1 INHIBITOR - TGFβ INHIBITOR BISPECIFIC DRUG MOIETIES.
|
CN115052625A
(zh)
|
2019-12-03 |
2022-09-13 |
埃沃特克国际有限责任公司 |
干扰素相关抗原结合蛋白及其用途
|
AU2020397416A1
(en)
|
2019-12-03 |
2022-07-14 |
Evotec International Gmbh |
Interferon-associated antigen binding proteins for use in treating hepatitis B infection
|
US20220356537A1
(en)
|
2019-12-31 |
2022-11-10 |
Roche Molecular Systems, Inc. |
Quantitative pcr screening of inducible prophage from bacterial isolates
|
US20230201315A1
(en)
|
2020-01-03 |
2023-06-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human |
Tnap locally administered for promoting periodontal health
|
US20230060095A1
(en)
|
2020-01-24 |
2023-02-23 |
Regeneron Pharmaceuticals, Inc. |
Preferentially expressed antigen in melanoma (prame) t cell receptors and methods of use thereof
|
MX2022013176A
(es)
|
2020-04-24 |
2022-11-30 |
Millennium Pharm Inc |
Anticuerpos anti cumulo de diferenciacion 19 (cd19) y sus usos.
|
EP4146697A1
(en)
|
2020-05-05 |
2023-03-15 |
Regeneron Pharmaceuticals, Inc. |
Car comprising cd28 zeta and cd3 zeta
|
KR20230069961A
(ko)
|
2020-09-14 |
2023-05-19 |
보르 바이오파마 인크. |
Cd33에 대한 단일 도메인 항체
|
JP2024505790A
(ja)
|
2020-12-18 |
2024-02-08 |
モメンタ ファーマシューティカルズ インコーポレイテッド |
インテグリンアルファ11ベータ1に対する抗体
|
JP2024515066A
(ja)
|
2021-04-09 |
2024-04-04 |
武田薬品工業株式会社 |
補体因子dを標的とする抗体及びその使用
|
US20230111279A1
(en)
|
2021-04-26 |
2023-04-13 |
Millennium Pharmaceuticals, Inc. |
Anti-clec12a antibodies and uses thereof
|
US20230018888A1
(en)
|
2021-04-26 |
2023-01-19 |
Millennium Pharmaceuticals, Inc. |
Anti-adgre2 antibodies and uses thereof
|
CA3217914A1
(en)
|
2021-05-04 |
2022-11-10 |
Kevin BRAY |
Chimeric antigen receptors with mage-a4 specificity and uses thereof
|
WO2022234003A1
(en)
|
2021-05-07 |
2022-11-10 |
Avacta Life Sciences Limited |
Cd33 binding polypeptides with stefin a protein
|
WO2022240824A1
(en)
|
2021-05-13 |
2022-11-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Compositions and methods for treating sickle cell diseases
|
EP4351732A1
(en)
|
2021-06-09 |
2024-04-17 |
Evotec International GmbH |
Interferon-associated antigen binding proteins for use for the treatment or prevention of coronavirus infection
|
TW202332694A
(zh)
|
2021-10-07 |
2023-08-16 |
英商阿凡克塔生命科學公司 |
血清半衰期延長之pd-l1結合多肽
|
TW202334196A
(zh)
|
2021-10-07 |
2023-09-01 |
英商阿法克塔生命科學有限公司 |
Pd-l1結合多肽
|
WO2023064255A2
(en)
|
2021-10-15 |
2023-04-20 |
The Regents Of The University Of California |
Diagnosis and treatment of anti-pf4 induced thrombocytopenia
|
AU2022372894A1
(en)
|
2021-10-20 |
2024-04-18 |
Takeda Pharmaceutical Company Limited |
Compositions targeting bcma and methods of use thereof
|
WO2023081167A2
(en)
|
2021-11-02 |
2023-05-11 |
The Regents Of The University Of California |
P-selectin mutants and modulation of integrin-mediated signaling
|
WO2023089564A1
(en)
|
2021-11-19 |
2023-05-25 |
Janssen Biotech, Inc. |
Method of treating geographic atrophy with a gene therapy vector expressing soluble cd59
|
WO2023146807A1
(en)
|
2022-01-25 |
2023-08-03 |
The Regents Of The University Of California |
Vegf mutants and modulation of integrin-mediated signaling
|
WO2023201238A1
(en)
|
2022-04-11 |
2023-10-19 |
Vor Biopharma Inc. |
Binding agents and methods of use thereof
|
WO2023200897A1
(en)
|
2022-04-13 |
2023-10-19 |
The Regents Of The University Of California |
Use of viral il-6 in cancer therapy
|
WO2023240109A1
(en)
|
2022-06-07 |
2023-12-14 |
Regeneron Pharmaceuticals, Inc. |
Multispecific molecules for modulating t-cell activity, and uses thereof
|