ES2007411A6 - Procedimiento de preparar nuevos agentes psicoestimulantes. - Google Patents
Procedimiento de preparar nuevos agentes psicoestimulantes.Info
- Publication number
- ES2007411A6 ES2007411A6 ES8702717A ES8702717A ES2007411A6 ES 2007411 A6 ES2007411 A6 ES 2007411A6 ES 8702717 A ES8702717 A ES 8702717A ES 8702717 A ES8702717 A ES 8702717A ES 2007411 A6 ES2007411 A6 ES 2007411A6
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- phenyl
- general formula
- alkyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003368 psychostimulant agent Substances 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 230000014759 maintenance of location Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000003943 catecholamines Chemical class 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 239000000021 stimulant Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 239000011800 void material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
Abstract
PROCEDIMIENTO DE PREPARAR NUEVOS AGENTES PSICOESTIMULANTES, DE LA FORMULA GENERAL ICUYOS SUSTITUYENTES SE DEFINEN EN LA DESCRIPCION. EL PROCEDIMIENTO CONSISTE EN HACER REACCIONAR UN COMPUESTO DE LA SIGUIENTE FORMULA GENERAL II CON UN COMPUESTO DE LA SIGUIENTE FORMULA GENERAL IIIEN LAS CUALES A Y B SIGNIFICAN GRUPOS QUE O BIEN SON CAPACES DE FORMAR UN GRUPO -NH-RY CUANDO REACCIONAN ENTRE SI O BIEN COMPRENDEN DICHO GRUPO. LA INVENCION INCLUYE OTRAS VARIANTES DE DICHO PROCEDIMIENTO.LOS COMPUESTOS OBTENIDOS PUEDEN APLICARSE PARA LA PREPARACION DE COMPOSICIONES PSICOESTIMULANTES, CON UN NUEVO ESPECTRO DE ACTIVIDAD.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU864101A HU207280B (en) | 1986-09-25 | 1986-09-25 | Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2007411A6 true ES2007411A6 (es) | 1989-06-16 |
Family
ID=10966901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8702717A Expired ES2007411A6 (es) | 1986-09-25 | 1987-09-23 | Procedimiento de preparar nuevos agentes psicoestimulantes. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5075338A (es) |
EP (1) | EP0284621B1 (es) |
KR (1) | KR880701545A (es) |
AT (1) | ATE117204T1 (es) |
CS (1) | CS277418B6 (es) |
DD (1) | DD262226A5 (es) |
DE (1) | DE3751006T2 (es) |
DK (1) | DK282488D0 (es) |
ES (1) | ES2007411A6 (es) |
FI (1) | FI882474A (es) |
GE (1) | GEP19960656B (es) |
HU (1) | HU207280B (es) |
IL (1) | IL83905A (es) |
LT (2) | LT3531B (es) |
LV (2) | LV10709B (es) |
PL (1) | PL151642B1 (es) |
PT (1) | PT85799B (es) |
RU (1) | RU2007384C1 (es) |
SU (1) | SU1746882A3 (es) |
UA (3) | UA19171A (es) |
WO (1) | WO1988002254A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5430044A (en) * | 1987-02-06 | 1995-07-04 | Fisons Corporation | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties |
DE68925933T2 (de) * | 1988-08-12 | 1996-08-14 | Fisons Corp | Arylalkylamine und -amide mit krampflösender und nervenschützender Wirkung |
HUT58270A (en) * | 1989-06-02 | 1992-02-28 | Wyeth John & Brother Ltd | Process for producing amine derivatives and pharmaceutical compositions containing them |
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
HUT63579A (en) * | 1991-12-20 | 1993-09-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes |
DK1203761T3 (da) | 1994-12-08 | 2005-04-11 | Nps Pharma Inc | Calciumreceptoraktive forbindelser |
US6299901B1 (en) | 1995-01-13 | 2001-10-09 | Somerset Pharmaceuticals, Inc. | Methods and pharmaceutical compositions employing desmethylselegiline |
US6319954B1 (en) | 1995-01-13 | 2001-11-20 | Somerset Pharmaceuticals, Inc. | S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions |
US6348208B1 (en) * | 1995-01-13 | 2002-02-19 | Somerset Pharmaceuticals, Inc. | Methods and pharmaceutical compositions employing desmethylselegiline |
US6033682A (en) | 1995-01-13 | 2000-03-07 | Somerset Pharmaceuticals, Inc. | S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions |
NZ309980A (en) | 1995-06-07 | 2001-06-29 | Noven Pharma | Transdermal composition containing a blend of one or more polymers, one or more drugs that has a low molecular weight and is liquid at room temperature |
US6316022B1 (en) | 1995-06-07 | 2001-11-13 | Noven Pharmaceuticals, Inc. | Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures |
US5981599A (en) | 1996-05-01 | 1999-11-09 | Nps Pharmaceuticals, Inc. | Inorganic ion receptor active compounds |
CA2267315C (en) * | 1997-08-07 | 2008-01-08 | Fujimoto Brothers Co., Ltd. | Ethylamine derivatives |
JP4499208B2 (ja) * | 1998-10-29 | 2010-07-07 | 株式会社フジモト・コーポレーション | 新規な光学活性アミノペンタン誘導体 |
US7619005B2 (en) * | 2000-11-01 | 2009-11-17 | Cognition Pharmaceuticals Llc | Methods for treating cognitive impairment in humans with Multiple Sclerosis |
US20050059743A1 (en) * | 2000-11-01 | 2005-03-17 | Sention, Inc. | Methods for treating mild cognitive impairment and alzheimer's disease |
US20070117869A1 (en) * | 2000-11-01 | 2007-05-24 | Cognition Pharmaceuticals Llc | Methods for treating coginitive impairment and improving cognition |
CA2427388C (en) * | 2000-11-01 | 2011-12-20 | Sention, Inc. | Pharmaceutical compositions and uses for improving memory and learning impairments |
US20030232890A1 (en) * | 2000-11-01 | 2003-12-18 | Sention, Inc. | Methods for treating an impairment in memory consolidation |
WO2005000203A2 (en) | 2001-10-31 | 2005-01-06 | Sention, Inc. | Methods for treating cognitive impairment and improving cognition |
US20030119884A1 (en) * | 2000-11-01 | 2003-06-26 | Epstein Mel H. | Methods and compositions for regulating memory consolidation |
EP1935414A3 (en) * | 2001-05-02 | 2010-08-18 | Blanchette Rockefeller Neurosciences Institute | Carbonic anhydrase activators for enhancig learning and memory |
AU2002256422A1 (en) * | 2001-05-02 | 2002-11-11 | Blanchette Rockefeller Neurosciences Institute | Carbonic anhydrase activators for enhancing learning and memory |
TW200538181A (en) * | 2004-05-18 | 2005-12-01 | Brni Neurosciences Inst | Treatment of depressive disorders |
CA2758774C (en) | 2009-04-15 | 2015-02-03 | Research Triangle Institute | Monoamine reuptake inhibitors |
RU2714893C2 (ru) | 2014-12-05 | 2020-02-20 | Земмельвайс Юнивёрсити | Арилалкиламиновые соединения для применения для профилактики или лечения рака |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US485926A (en) | 1892-11-08 | Field | ||
DE767263C (de) * | 1937-10-03 | 1952-03-31 | Theodor H Temmler | Verfahren zur Herstellung von ª-Aralkylaminen |
DE893341C (de) * | 1950-08-23 | 1953-10-15 | Troponwerke Dinklage & Co | Verfahren zur Herstellung von N-Aralkyl-ª-phenyl-isopropylaminen |
US2797242A (en) * | 1953-08-11 | 1957-06-25 | Parke Davis & Co | Substituted alpha-benzylphenethylamines and methods for producing the same |
DE227447C (es) | 1955-03-23 | 1910-10-21 | ||
DE1210873B (de) * | 1959-03-18 | 1966-02-17 | Hoffmann La Roche | Verfahren zur Herstellung von Halogenalkylaminen |
US3044932A (en) * | 1960-02-24 | 1962-07-17 | Upjohn Co | Appetite suppressant drugs |
DE1133395B (de) * | 1960-11-12 | 1962-07-19 | Hoechst Ag | Verfahren zur Herstellung von herz- und kreislaufwirksamen Phenylalkylaminen |
GB1031425A (en) * | 1962-03-30 | 1966-06-02 | Chinoin Gyogyszer Es Vegyeszet | New aralkylamines and their preparation |
DE1227447B (de) * | 1962-03-30 | 1966-10-27 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von Phenylisopropylaminen |
FR1478311A (fr) * | 1963-10-18 | 1967-04-28 | Koninklijke Pharma Fab Nv | Procédé de préparation d'aminoalcanes et produits en résultant |
GB1218135A (en) * | 1967-07-28 | 1971-01-06 | Abbott Lab | Substituted phenethylamine derivatives |
DE2143204C3 (de) * | 1971-08-28 | 1979-09-27 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt | N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis |
US4025624A (en) * | 1975-11-18 | 1977-05-24 | A. H. Robins Company, Incorporated | Phenylalkylamines and phenylalkylureas in combinations to suppress gastric bleeding in aspirin therapy |
US4404222A (en) * | 1980-08-25 | 1983-09-13 | American Cyanamid Company | Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby |
DD145599A1 (de) * | 1979-08-23 | 1980-12-24 | Roswitha Toepfer | Mittel zur regulierung des pflanzenwachstums |
-
1986
- 1986-09-25 HU HU864101A patent/HU207280B/hu not_active IP Right Cessation
-
1987
- 1987-09-15 IL IL83905A patent/IL83905A/xx not_active IP Right Cessation
- 1987-09-21 DD DD87307094A patent/DD262226A5/de not_active IP Right Cessation
- 1987-09-23 ES ES8702717A patent/ES2007411A6/es not_active Expired
- 1987-09-25 UA UA4742460A patent/UA19171A/uk unknown
- 1987-09-25 EP EP87906316A patent/EP0284621B1/en not_active Expired - Lifetime
- 1987-09-25 UA UA4355858A patent/UA11100A/uk unknown
- 1987-09-25 PT PT85799A patent/PT85799B/pt not_active IP Right Cessation
- 1987-09-25 DE DE3751006T patent/DE3751006T2/de not_active Expired - Fee Related
- 1987-09-25 WO PCT/HU1987/000040 patent/WO1988002254A1/en active IP Right Grant
- 1987-09-25 AT AT87906316T patent/ATE117204T1/de not_active IP Right Cessation
- 1987-09-25 CS CS876898A patent/CS277418B6/cs unknown
- 1987-09-25 PL PL1987267913A patent/PL151642B1/pl unknown
-
1988
- 1988-05-24 DK DK282488A patent/DK282488D0/da not_active Application Discontinuation
- 1988-05-24 SU SU884355858A patent/SU1746882A3/ru active
- 1988-05-24 KR KR1019880700574A patent/KR880701545A/ko not_active Application Discontinuation
- 1988-05-25 FI FI882474A patent/FI882474A/fi not_active IP Right Cessation
-
1989
- 1989-10-11 US US07/420,058 patent/US5075338A/en not_active Expired - Fee Related
- 1989-11-23 RU SU894742460A patent/RU2007384C1/ru active
-
1990
- 1990-09-10 UA UA4830945A patent/UA19808A/uk unknown
-
1993
- 1993-06-22 LV LVP-93-651A patent/LV10709B/lv unknown
- 1993-06-22 LV LVP-93-650A patent/LV10860B/lv unknown
- 1993-08-12 GE GEAP19931393A patent/GEP19960656B/en unknown
- 1993-08-19 LT LTIP879A patent/LT3531B/lt not_active IP Right Cessation
- 1993-08-19 LT LTIP878A patent/LT3530B/lt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
LV10709B (en) | 1995-12-20 |
LV10709A (lv) | 1995-06-20 |
EP0284621B1 (en) | 1995-01-18 |
HU207280B (en) | 1993-03-29 |
UA11100A (uk) | 1996-12-25 |
FI882474A0 (fi) | 1988-05-25 |
UA19808A (uk) | 1997-12-25 |
DD262226A5 (de) | 1988-11-23 |
ATE117204T1 (de) | 1995-02-15 |
IL83905A (en) | 1993-07-08 |
PL151642B1 (en) | 1990-09-28 |
LTIP878A (en) | 1995-03-27 |
GEP19960656B (en) | 1996-12-24 |
UA19171A (uk) | 1997-12-25 |
DE3751006D1 (de) | 1995-03-02 |
DE3751006T2 (de) | 1995-05-24 |
EP0284621A1 (en) | 1988-10-05 |
LV10860A (lv) | 1995-10-20 |
WO1988002254A1 (en) | 1988-04-07 |
RU2007384C1 (ru) | 1994-02-15 |
KR880701545A (ko) | 1988-11-03 |
CS689887A3 (en) | 1992-08-12 |
DK282488A (da) | 1988-05-24 |
LT3531B (en) | 1995-11-27 |
LTIP879A (en) | 1995-03-27 |
LV10860B (en) | 1996-04-20 |
US5075338A (en) | 1991-12-24 |
PT85799B (pt) | 1990-08-31 |
FI882474A (fi) | 1988-05-25 |
PT85799A (en) | 1987-10-01 |
PL267913A1 (en) | 1989-03-06 |
SU1746882A3 (ru) | 1992-07-07 |
LT3530B (en) | 1995-11-27 |
DK282488D0 (da) | 1988-05-24 |
HUT45962A (en) | 1988-09-28 |
CS277418B6 (en) | 1993-03-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2007-09-23 |
|
FD1A | Patent lapsed |
Effective date: 20000601 |